Ligand D-glucuronyl beta-1,2-D-glucuronic acid
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Basic Ligand Information
Molecular Structure

C12H18O13
D-glucuronyl beta-1,2-D-glucuronic acid
IMNADAQGVSDVMI-MUAZRATOSA-N
1,2-beta-D-glucuronosyl-D-glucuronate, beta-D-glucuronosyl-(1->2)-D-glucuronate
Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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glycyrrhizinic acid + H2O = glycyrrhetinic acid + D-glucuronyl beta-1,2-D-glucuronic acid
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Product in Enzyme-catalyzed Reactions (1 result)
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glycyrrhizinic acid + H2O = glycyrrhetinic acid + D-glucuronyl beta-1,2-D-glucuronic acid
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Enzyme Kinetic Parameters
References & Links
Literature References (5)
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Distribution of enzymes involved in the metabolism of glycyrrhizin in various organs of rat
1998
Akao, T.
Biol. Pharm. Bull.
21
1036-1044
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Purification and some properties of glycyrrhizinic acid hydrolase from Aspergillus niger GRM3
1986
Muro, T.; Kuramoto, T.; Imoto, K.; Okada, S.
Agric. Biol. Chem.
50
687-692
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Substrate specificity of glycyrrhizinic acid hydrolase
1988
Sasaki, Y.; Morita, T.; Kuramoto, T.; Mizutani, K.; Ikeda, R.; Tanaka, O.
Agric. Biol. Chem.
52
207-210
Glycyrrhizin beta-D-glucuronidase of Eubacterium sp. from human intestinal flora
1987
Akao, Ta.; Akao, Te.; Kobashi, K.
Chem. Pharm. Bull.
35
705-710
Intestinal bacterial hydrolysis is indispensable to absorption of 18beta-glycyrrhetic acid after oral administration of glycyrrhizin in rats
1994
Akao, T.; Hayashi, T.; Kobashi, K.; Kanaoka, M.; Kato, H.; Kobayashi, M.; Takeda, S.; Oyama, T.
J. Pharm. Pharmacol.
46
135-137
Links to other databases for D-glucuronyl beta-1,2-D-glucuronic acid