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Ligand alpha-L-fucosyl-1,2-D-galactose Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C1 2 H2 2 O1 0
alpha-L-fucosyl-1,2-D-galactose
VSRVRBXGIRFARR-UHFFFAOYSA-N
2-O-alpha-L-fucopyranosyl-D-galactose, alpha-L-fucosyl-(1,2)-D-galactose
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
UDP-galactose + alpha-L-fucosyl-(1,2)-D-galactose = UDP + alpha-D-galactosyl-(1,3)-[alpha-L-fucosyl(1,2)]-D-galactose
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Substrate in Enzyme-catalyzed Reactions (2 results)
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UDP-galactose + alpha-L-fucosyl-(1,2)-D-galactose = UDP + alpha-D-galactosyl-(1,3)-[alpha-L-fucosyl(1,2)]-D-galactose
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2-O-alpha-L-fucopyranosyl-D-galactose + H2O = L-fucose + galactose
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Product in Enzyme-catalyzed Reactions (1 result)
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GDP-L-fucose + D-galactose = GDP + alpha-L-fucosyl-1,2-D-galactose
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Enzyme Kinetic Parameters
References & Links Literature References (5)
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Glycosidases of Aspergillus niger. II. Purification and general properties of 1,2-alpha-L-fucosidase
1970
Bahl, O.P.
J. Biol. Chem.
245
299-304
alpha-L-Fucosidases from almond emulsin: characterization of the two enzymes with different specificities
1977
Ogata-Arakawa, M.; Muramatsu, T.; Kobata, A.
Arch. Biochem. Biophys.
181
353-358
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Phenyl beta-D-galactosylpyranoside as an acceptor substrate for the blood-group H gene-associated guanosine diphosphate L-fucose:beta-D-galactosyl alpha-2-L-fucosyltransferase
1976
Chester, M.A.; Yates, A.D.; Watkins, W.M.
Eur. J. Biochem.
69
583-592
Comparative study of substrate and product binding to the human ABO(H) blood group glycosyltransferases
2009
Soya, N.; Shoemaker, G.K.; Palcic, M.M.; Klassen, J.S.
Glycobiology
19
1224-1234
Binding of an acceptor substrate analog enhances the enzymatic activity of human blood group B galactosyltransferase
2010
Sindhuwinata, N.; Munoz, E.; Munoz, F.J.; Palcic, M.M.; Peters, H.; Peters, T.
Glycobiology
20
718-723
Links to other databases for alpha-L-fucosyl-1,2-D-galactose
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