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Ligand 8-Bromoguanosine

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Product in Enzyme-catalyzed Reactions (1 result)

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Show Product (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.11.1.10

guanosine + Br- + H2O2 = 8-bromoguanosine + H2O

348310

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Inhibitor in Enzyme-catalyzed Reactions (2 results)

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Show Inhibitors (2 entries)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

2.4.2.1

about 25% inhibition

758637

4da8, 3D-view

2.4.2.1

about 30% inhibition

758637

4da8, 3D-view

2.4.2.1

2 entries

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

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Show 3D Structure of Enzyme-Ligand-Complex (PDB) (1 entry)

EC NUMBER

ENZYME 3D STRUCTURE

2.4.2.1

4da8, 3D-view

Enzyme Kinetic Parameters

References & Links

Literature References (2)

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Show Reference (2 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

348310

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Haloperoxidase-catalyzed halogenation of nitrogen-containing aromatic heterocycles represented by nucleic bases

1987

Itoh, N.; Izumi, Y.; Yamada, H.

Biochemistry

26

282-289

758637

27769382

Development, validation and application of a 96-well enzymatic assay based on LC-ESI-MS/MS quantification for the screening of selective inhibitors against Mycobacterium tuberculosis purine nucleoside phosphorylase

2016

Cattaneo, G.; Ubiali, D.; Calleri, E.; Rabuffetti, M.; Hoefner, G.C.; Wanner, K.T.; De Moraes, M.C.; Martinelli, L.K.B.; Santos, D.S.; Speranza, G.; Massolini, G.

Anal. Chim. Acta

943

89-97

Links to other databases for 8-Bromoguanosine

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Show Links (1 entry)

ChEBI

PubChem

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