Ligand 3alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA
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Basic Ligand Information
C48H80N7O19P3S
3alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA
SBYLHTNKEWSLBA-NOMRFMDASA-N
(25R)-3alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA, (25R)-dihydroxycholestanoyl-CoA[side 1], (25R)-dihydroxycholestanoyl-CoA[side 2]
Related pathways
MetaCyc
bile acid biosynthesis, neutral pathway
Show all BRENDA pathways known for 3alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (1 result)
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ATP + H2O + (25R)-dihydroxycholestanoyl-CoA[side 1] = ADP + phosphate + (25R)-dihydroxycholestanoyl-CoA[side 2]
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Product in Enzyme-catalyzed Reactions (2 results)
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ATP + 3alpha,7alpha-dihydroxy-5beta-cholestanate + CoA = AMP + diphosphate + 3alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA
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ATP + H2O + (25R)-dihydroxycholestanoyl-CoA[side 1] = ADP + phosphate + (25R)-dihydroxycholestanoyl-CoA[side 2]
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Enzyme Kinetic Parameters
References & Links
Literature References (2)
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Subcellular localization of 3alpha,7alpha-dihydroxy- and 3alpha,7alpha,12alpha-trihydroxy-5beta-cholastanoyl-coenzyme A ligase(s) in rat liver
1988
Prydz, K.; Kase, B.F.; Bjoerkhem, I.; Pedersen, J.I.
J. Lipid Res.
29
997-1004
Biogenesis and function of peroxisomes in human disease with a focus on the ABC transporter
2019
Imanaka, T.
Biol. Pharm. Bull.
42
649-665
Links to other databases for 3alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA