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Ligand 4-chloro-2-methylphenol

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Natural Substrate (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.14.13.20

4-chloro-2-methylphenol + NADPH + O2 = ?

671456

-

In Vivo Product in Enzyme-catalyzed Reactions (3 results)

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Show Natural Product (3 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.14.11.43

(R)-2-(4-chloro-2-methylphenoxy)propanoate + 2-oxoglutarate + O2 = 2-methyl-4-chlorophenol + pyruvate + succinate + CO2

0

-

1.14.11.43

(S)-2-(4-chloro-2-methylphenoxy)propanoate + 2-oxoglutarate + O2 = 4-chloro-2-methylphenol + pyruvate + succinate + CO2

0

-

1.14.11.43

2 entries

1.14.11.44

(R)-2-(4-chloro-2-methylphenoxy)propanoate + 2-oxoglutarate + O2 = 4-chloro-2-methylphenol + pyruvate + succinate + CO2

0

-

Substrate in Enzyme-catalyzed Reactions (4 results)

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Show Substrate (4 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.10.3.2

4-chloro-2-methylphenol + O2 = ? + H2O

396354

-

1.14.13.20

4-chloro-2-methylphenol + NADPH + O2 = 5-chloro-3-methylcatechol + NADP+ + H2O

724636

-

1.14.13.20

4-chloro-2-methylphenol + NADPH + O2 = ?

439012, 671456, 439011, 439016

-

1.14.13.20

2 entries

2.4.1.218

UDP-glucose + 4-chloro-2-methylphenol = UDP + 1-O-(4-chloro-2-methylphenyl)-beta-D-glucopyranoside

393094

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Product in Enzyme-catalyzed Reactions (3 results)

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Show Product (3 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.14.11.43

(R)-2-(4-chloro-2-methylphenoxy)propanoate + 2-oxoglutarate + O2 = 2-methyl-4-chlorophenol + pyruvate + succinate + CO2

0

-

1.14.11.43

(S)-2-(4-chloro-2-methylphenoxy)propanoate + 2-oxoglutarate + O2 = 4-chloro-2-methylphenol + pyruvate + succinate + CO2

0

-

1.14.11.43

2 entries

1.14.11.44

(R)-2-(4-chloro-2-methylphenoxy)propanoate + 2-oxoglutarate + O2 = 4-chloro-2-methylphenol + pyruvate + succinate + CO2

0

-

Enzyme Kinetic Parameters

References & Links

Literature References (7)

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Show Reference (7 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

393094

11937332

Arbutin synthase, a novel member of the NRD1beta glycosyltransferase family, is a unique multifunctional enzyme converting various natural products and xenobiotics

2002

Hefner, T.; Arend, J.; Warzecha, H.; Siems, K.; Stöckigt, J.

Bioorg. Med. Chem.

10

1731-1741

396354

-

Soluble and immobilized laccase as catalysts for the transformation of substituted phenols

1986

Shuttleworth, K.L.; Bollag, J.M.

Enzyme Microb. Technol.

8

171-177

439011

7075592

The purification and properties of 2,4-dichlorophenol hydroxylase from a strain of Acinetobacter species

1982

Beadle, C.A.; Smith, A.R.W.

Eur. J. Biochem.

123

323-332

439012

6745439

Purification and properties of a plasmid-encoded 2,4-dichlorophenol hydroxylase

1984

Liu, T.; Chapman, P.J.

FEBS Lett.

173

314-318

439016

9418244

Purification and characterization of 2,4-dichlorophenol hydroxylase isolated from a bacterium of the alpha-2 subgroup of the Proteobacteria

1997

Makdessi, K.; Lechner, U.

FEMS Microbiol. Lett.

157

95-101

671456

16597983

Chlorophenol hydroxylases encoded by plasmid pJP4 differentially contribute to chlorophenoxyacetic acid degradation

2006

Ledger, T.; Pieper, D.H.; Gonzalez, B.

Appl. Environ. Microbiol.

72

2783-2792

724636

21293902

Cloning and characterisation of a novel 2,4-dichlorophenol hydroxylase from a metagenomic library derived from polychlorinated biphenyl-contaminated soil

2011

Lu, Y.; Yu, Y.; Zhou, R.; Sun, W.; Dai, C.; Wan, P.; Zhang, L.; Hao, D.; Ren, H.

Biotechnol. Lett.

33

1159-1167

Links to other databases for 4-chloro-2-methylphenol

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Show Links (1 entry)

ChEBI

PubChem