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Ligand 3-oxoadipyl-CoA Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C2 7 H4 2 N7 O2 0 P3 S
3-oxoadipyl-CoA
VKKKAAPGXHWXOO-BIEWRJSYSA-N
Show all BRENDA pathways known for 3-oxoadipyl-CoA
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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CoA + 3-oxoadipyl-CoA = succinyl-CoA + acetyl-CoA
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In Vivo Product in Enzyme-catalyzed Reactions (3 results)
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(3S)-3-hydroxyadipyl-CoA + NAD+ = 3-oxoadipyl-CoA + NADH + H+
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3-oxoadipate + succinyl-CoA = 3-oxoadipyl-CoA + succinate
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succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA
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Substrate in Enzyme-catalyzed Reactions (1 result)
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CoA + 3-oxoadipyl-CoA = succinyl-CoA + acetyl-CoA
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Product in Enzyme-catalyzed Reactions (3 results)
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(3S)-3-hydroxyadipyl-CoA + NAD+ = 3-oxoadipyl-CoA + NADH + H+
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3-oxoadipate + succinyl-CoA = 3-oxoadipyl-CoA + succinate
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succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA
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Enzyme Kinetic Parameters
kcat Value (Turnover Number) (1 result)
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KM Value (1 result)
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References & Links Literature References (3)
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Enzymatic degradation of beta-ketoadipic acid
1957
Katagiri, M.; Hayaishi, O.
J. Biol. Chem.
226
439-448
Degradation of aromatics and chloroaromatics by Pseudomonas sp. strain B13: cloning, characterization, and analysis of sequences encoding 3-oxoadipate:succinyl-coenzyme A (CoA) transferase and 3-oxoadipyl-CoA thiolase
2002
Gobel, M.; Kassel-Cati, K.; Schmidt, E.; Reineke, W.
J. Bacteriol.
184
216-223
Degradation of aromatics and chloroaromatics by Pseudomonas sp. strain B13: purification and characterization of 3-oxoadipate:succinyl-coenzyme A (CoA) transferase and 3-oxoadipyl-CoA thiolase
2002
Kaschabek, S.R.; Kuhn, B.; Muller, D.; Schmidt, E.; Reineke, W.
J. Bacteriol.
184
207-215
Links to other databases for 3-oxoadipyl-CoA