Ligand 5-methyl-1-naphthoate
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Basic Ligand Information
C12H10O2
5-methyl-1-naphthoate
VLEZTIKHFUAVRK-UHFFFAOYSA-N
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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5-methyl-1-naphthoate + NADPH + H+ + O2 = 3-hydroxy-5-methyl-1-naphthoate + NADP+ + H2O
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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acetyl-CoA + 5 malonyl-CoA + 3 NADPH + 3 H+ = 5-methyl-1-naphthoate + 6 CoA + 5 CO2 + 4 H2O + 3 NADP+
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Substrate in Enzyme-catalyzed Reactions (1 result)
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5-methyl-1-naphthoate + NADPH + H+ + O2 = 3-hydroxy-5-methyl-1-naphthoate + NADP+ + H2O
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Product in Enzyme-catalyzed Reactions (1 result)
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acetyl-CoA + 5 malonyl-CoA + 3 NADPH + 3 H+ = 5-methyl-1-naphthoate + 6 CoA + 5 CO2 + 4 H2O + 3 NADP+
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Enzyme Kinetic Parameters
References & Links
Literature References (1)
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Biosynthesis of 3-methoxy-5-methyl naphthoic acid and its incorporation into the antitumor antibiotic azinomycin B
2010
Ding, W.; Deng, W.; Tang, M.; Zhang, Q.; Tang, G.; Bi, Y.; Liu, W.
Mol. Biosyst.
6
1071-1081
Links to other databases for 5-methyl-1-naphthoate