Ligand propylene oxide

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of propylene oxide (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C3H6O
propylene oxide
GOOHAUXETOMSMM-UHFFFAOYSA-N
Synonyms:
(R)-[or (S)-]1,2-epoxypropane, 1,2-Epoxypropane, 2-methyloxirane, epoxypropane, propene oxide, propylene epoxide
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
epoxypropane + HS-CoM = 2-hydroxypropyl-CoM
show the reaction diagram
-
epoxypropane + glutathione = 2-(glutathion-S-yl)-propan-1-ol
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
propylene oxide + H2O = ?
show the reaction diagram
-
epoxypropane + glutathione = 2-(glutathion-S-yl)-propan-1-ol
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (25 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
propene + H2O2 = 2-methyloxirane + H2O
show the reaction diagram
-
-
propene + O2 + NADH + H+ = propylene oxide + NAD+ + H2O
show the reaction diagram
-
-
2-hydroxypropyl-CoM = 1,2-epoxypropane + HS-CoM
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
product inhibition at higher concentration
-
15% residual activity at 6 M (pH 4.0)
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
6.5
-
-

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0018
-
-

References & Links

Links to other databases for propylene oxide

ChEBI
PubChem
-
PubChem