Ligand cellobionic acid
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Basic Ligand Information
Molecular Structure

C12H22O12
cellobionic acid
JYTUSYBCFIZPBE-ZNLUKOTNSA-N
4-O-beta-D-glucopyranosyl-D-gluconate, 4-O-beta-D-glucopyranosyl-D-gluconic acid, cellobionate
Show all BRENDA pathways known for cellobionic acid
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)
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4-O-beta-D-glucopyranosyl-D-gluconate + phosphate = alpha-D-glucose 1 phosphate + D-gluconate
4-O-beta-D-glucopyranosyl-D-gluconate + phosphate = alpha-D-glucose 1-phosphate + D-gluconate
In Vivo Product in Enzyme-catalyzed Reactions (2 results)
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alpha-D-glucose 1 phosphate + D-gluconate = 4-O-beta-D-glucopyranosyl-D-gluconate + phosphate
alpha-D-glucose 1-phosphate + D-gluconate = 4-O-beta-D-glucopyranosyl-D-gluconate + phosphate
Substrate in Enzyme-catalyzed Reactions (3 results)
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cellobionate + acceptor = ?
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4-O-beta-D-glucopyranosyl-D-gluconate + phosphate = alpha-D-glucose 1 phosphate + D-gluconate
4-O-beta-D-glucopyranosyl-D-gluconate + phosphate = alpha-D-glucose 1-phosphate + D-gluconate
Product in Enzyme-catalyzed Reactions (3 results)
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phosphoric acid swollen cellulose + ascorbic acid + O2 = cellobionic acid + ? + dehydroascorbate + H2O
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alpha-D-glucose 1 phosphate + D-gluconate = 4-O-beta-D-glucopyranosyl-D-gluconate + phosphate
alpha-D-glucose 1-phosphate + D-gluconate = 4-O-beta-D-glucopyranosyl-D-gluconate + phosphate
Activator in Enzyme-catalyzed Reactions (1 result)
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activates, chelates Mn3+
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Inhibitor in Enzyme-catalyzed Reactions (2 results)
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inhibits competitive Mn(III)-malonate formation
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3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)
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Enzyme Kinetic Parameters
kcat Value (Turnover Number) (1 result)
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KM Value (1 result)
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Ki Value (1 result)
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References & Links
Literature References (5)
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Hexopyranoside: cytochrome c oxidoreductase from Agrobacterium
1975
Van Beeumen, J.; De Ley, J.
Methods Enzymol.
41
153-158
Manganese(II) oxidation by manganese peroxidase from the basidiomycete Phanerochaete chrysosporium. Kinetic mechanism and role of chelators
1992
Wariishi, H.; Valli, K.; Gold, M.H.
J. Biol. Chem.
267
23688-23695
Discovery of cellobionic acid phosphorylase in cellulolytic bacteria and fungi
2013
Nihira, T.; Saito, Y.; Nishimoto, M.; Kitaoka, M.; Igarashi, K.; Ohtsubo, K.; Nakai, H.
FEBS Lett.
587
3556-3561
Cellobionic acid utilization: from Neurospora crassa to Saccharomyces cerevisiae
2015
Li, X.; Chomvong, K.; Yu, V.Y.; Liang, J.M.; Lin, Y.; Cate, J.H.
Biotechnol. Biofuels
8
120
Crystal structure and substrate recognition of cellobionic ccid phosphorylase, which plays a key role in oxidative cellulose degradation by microbes
2015
Nam, Y.W.; Nihira, T.; Arakawa, T.; Saito, Y.; Kitaoka, M.; Nakai, H.; Fushinobu, S.
J. Biol. Chem.
290
18281-18292
Links to other databases for cellobionic acid