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Ligand adenine645 in 25S rRNA

Basic Ligand Information

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Natural Substrate (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.1.1.287

S-adenosyl-L-methionine + adenine645 in 25S rRNA = S-adenosyl-L-homocysteine + N1-methyladenine645 in 25S rRNA

723299, 758419

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Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Substrate (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.1.1.287

S-adenosyl-L-methionine + adenine645 in 25S rRNA = S-adenosyl-L-homocysteine + N1-methyladenine645 in 25S rRNA

723299, 758419

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Enzyme Kinetic Parameters

References & Links

Literature References (3)

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Show Reference (3 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

723299

23180764

Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA

2013

Peifer, C.; Sharma, S.; Watzinger, P.; Lamberth, S.; Kotter, P.; Entian, K.D.

Nucleic Acids Res.

41

1151-1163

758419

30093689

A single N1-methyladenosine on the large ribosomal subunit rRNA impacts locally its structure and the translation of key metabolic enzymes

2018

Sharma, S.; Hartmann, J.; Watzinger, P.; Klepper, A.; Peifer, C.; Koetter, P.; Lafontaine, D.; Entian, K.

Sci. Rep.

8

11904

758419

30093689

A single N1-methyladenosine on the large ribosomal subunit rRNA impacts locally its structure and the translation of key metabolic enzymes

2018

Sharma, S.; Hartmann, J.; Watzinger, P.; Klepper, A.; Peifer, C.; Koetter, P.; Lafontaine, D.; Entian, K.

Sci. Rep.

8

11904

758419

2 entries

Links to other databases for adenine645 in 25S rRNA

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