Ligand 4-hydroxy-2-oxoheptane-1,7-dioate

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Basic Ligand Information

Molecular Structure
Picture of 4-hydroxy-2-oxoheptane-1,7-dioate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C7H10O6
4-hydroxy-2-oxoheptane-1,7-dioate
HNOAJOYERZTSNK-UHFFFAOYSA-N
Synonyms:
(4RS)-4-hydroxy-2-oxoheptane-1,7-dioate, 2-oxo-4-hydroxyhepta-1,7-dioate, 4-hydroxy-2-ketoheptane-1,7-dioate, 4-hydroxy-2-oxo-1,7-heptanedioate, 4-hydroxy-2-oxo-heptanedioate, 4-hydroxy-2-oxoheptanedioate


Show all pahtways known for Show all BRENDA pathways known for 4-hydroxy-2-oxoheptane-1,7-dioate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
pyruvate + succinic semialdehyde = 4-hydroxy-2-oxo-1,7-heptanedioate
show the reaction diagram
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-

Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-hydroxy-2-ketoheptane-1,7-dioate = pyruvate + succinic semialdehyde
show the reaction diagram
-
4-hydroxy-2-oxoheptane-1,7-dioate = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
pyruvate + succinic semialdehyde = 4-hydroxy-2-oxo-1,7-heptanedioate
show the reaction diagram
-
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pyruvate + succinic semialdehyde = (4RS)-4-hydroxy-2-oxoheptane-1,7-dioate
show the reaction diagram
-
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (5 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
361.5
-
using H2O as solvent, in the presence of 0.5 mM Co2+, at pH 8.0 and 25°C

KM Value (5 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.35
-
using H2O as solvent, in the presence of 0.5 mM Co2+, at pH 8.0 and 25°C

References & Links

Links to other databases for 4-hydroxy-2-oxoheptane-1,7-dioate

ChEBI
PubChem
ChEBI
PubChem