Ligand L-2-chloropropionate

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Basic Ligand Information

Molecular Structure
Picture of L-2-chloropropionate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C3H5ClO2
L-2-chloropropionate
FHMMQQXRSYSWCM-UHFFFAOYSA-N
Synonyms:
(S)-2-chloropropanoate, (S)-2-chloropropionic acid, L-2-monochloropropionate
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-2-chloropropionic acid + H2O = (R)-2-hydroxypropionic acid + chloride
show the reaction diagram

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-chloroacrylate + NADPH + H+ = (S)-2-chloropropanoate + NADP+
show the reaction diagram
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-

Substrate in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-2-chloropropionate + H2O = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-chloroacrylate + NADPH + H+ = (S)-2-chloropropanoate + NADP+
show the reaction diagram
-
-
chloroacrylic acid + NADPH = (S)-2-chloropropionic acid + NADP+
show the reaction diagram
-
-
4-nitrophenyl 2-chloropropionate + H2O = 4-nitrophenol + (S)-2-chloropropionic acid
show the reaction diagram
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-
(R,S)-2-chloropropionic acid + H2O = (S)-lactic acid + (S)-2-chloropropionic acid + HCl
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
inhibits dehalogenation of D-2-chloropropionate
-

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
47
-
comparison with mutant enzymes

KM Value (17 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
6.5
-
pH 9.5, 30°C

References & Links

Links to other databases for L-2-chloropropionate

ChEBI
PubChem
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PubChem