Ligand GlcNAcbeta(1->2)Manalpha(1->6)[GlcNAcbeta(1->2)Manalpha(1->3)]Manbeta(1->4)GlcNAcbeta(1->4)[L-Fucalpha(1->6)]GlcNAc
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Basic Ligand Information
Molecular Structure

C56H94N4O40
GlcNAcbeta(1->2)Manalpha(1->6)[GlcNAcbeta(1->2)Manalpha(1->3)]Manbeta(1->4)GlcNAcbeta(1->4)[L-Fucalpha(1->6)]GlcNAc
DWCNMHMZSYJSGO-ZDCZPVQISA-N
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (1 result)
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GDP-beta-L-fucose + GlcNAcbeta(1->2)Manalpha(1->6)[GlcNAcbeta(1->2)Manalpha(1->3)]Manbeta(1->4)GlcNAcbeta(1->4)[L-Fucalpha(1->6)]GlcNAc = GDP + GlcNAcbeta(1->2)Manalpha(1->6)[GlcNAcbeta(1->2)Manalpha(1->3)]Manbeta(1->4)GlcNAcbeta(1->4)[L-Fucalpha(1->3)][L-Fucalpha(1->6)]GlcNAc
-
Enzyme Kinetic Parameters
KM Value (1 result)
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1
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at 25°C, pH not specified in the publication
References & Links
Literature References (2)
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Distantly related plant and nematode core alpha1,3-fucosyltransferases display similar trends in structure-function relationships
2011
Both, P.; Sobczak, L.; Breton, C.; Hann, S.; Noebauer, K.; Paschinger, K.; Kozmon, S.; Mucha, J.; Wilson, I.B.
Glycobiology
21
1401-1415
Formation of the immunogenic alpha1,3-fucose epitope: elucidation of substrate specificity and of enzyme mechanism of core fucosyltransferase A
2012
Koetzler, M.P.; Blank, S.; Behnken, H.N.; Alpers, D.; Bantleon, F.I.; Spillner, E.; Meyer, B.
Insect Biochem. Mol. Biol.
42
116-125
Links to other databases for GlcNAcbeta(1->2)Manalpha(1->6)[GlcNAcbeta(1->2)Manalpha(1->3)]Manbeta(1->4)GlcNAcbeta(1->4)[L-Fucalpha(1->6)]GlcNAc