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Biosynthesis of streptomycin. dTDP-dihydrostreptose synthase from Streptomyces griseus and dTDP-4-keto-L-rhamnose 3,5-epimerase from S. griseus and Escherichia coli Y10
1979
Wahl, H.P.; Grisebach, H.
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Two enzymes in Streptomyces griseus for the synthesis of dTDP-L-dihydrostreptose from dTFP-6-deoxy-D-xylo-4-hexosulose
1975
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Enzymatic synthesis and isolation of thymidine diphosphate-6-deoxy-D-xylo-4-hexulose and thymidine diphosphate-L-rhamnose
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Purification of thymidine-diphospho-D-glucose 4,6-dehydratase from an erythromycin-producing strain of Saccharospora erythraea by high resolution liquid chromatography
1988
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Dehydration in nucleotide-linked deoxysugar synthesis
1971
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The mechanism of 6-deoxyhexose synthesis. I. Intramolecular hydrogen transfer catalyzed by deoxythymidine diphosphate-D-glucose oxidoreductase
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Thymidine diphosphate 4-acetamido-4,6-dideoxyhexoses. II. Purification and properties of thymidine diphosphate D-glucose oxidoreductase
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High level expression and purification of dThymidine diphospho-D-glucose 4,6-dehydratase (rfbB) from Salmonella serovar typhimurium LT2
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Cloning of the genes encoding thymidine diphosphoglucose 4,6-dehydratase and thymidine diphospho-4-keto-6-deoxyglucose 3,5-epimerase from the erythomycin-producing Saccharopolyspora erythraea
1995
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Substrate specificity of native dTDP-D-glucose-4,6-dehydratase. Chemo-enzymatic syntheses of artificial and naturally occuring deoxy sugars
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Combined preparative enzymatic synthesis of dTDP-6-deoxy-4-keto-D-glucose from dTDP and sucrose
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A novel NDP-6-deoxyhexosyl-4-ulose reductase in the pathway for the synthesis of thymidine diphosphate-D-fucose
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The mechanism of 6-deoxyhexose synthesis. II. Conversion of deoxythymidine diphosphate 4-keto-6-deoxy-D-glucose to deoxythymidine diphosphate L-rhamnose
1968
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Characterization of dTDP-4-dehydrorhamnose 3,5-epimerase and dTDP-4-dehydrorhamnose reductase, required for dTDP-L-rhamnose biosynthesis in Salmonella enterica serovar typhimurium LT2
1999
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1966
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The purification, crystallization and structural elucidation of dTDP-D-glucose 4,6-dehydratase (RmlB), the second enzyme of the dTDP-L-rhamnose synthesis pathway from Salmonella enterica serovar typhimurium
2000
Allard, S.T.; Giraud, M.F.; Whitfield, C.; Messner, P.; Naismith, J.H.
Acta Crystallogr. Sect. D
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Characterization of enzymatic processes by rapid mix-quench mass spectrometry: the case of dTDP-glucose 4,6-dehydratase
2000
Gross, J.W.; Hegeman, A.D.; Vestling, M.M.; Frey, P.A.
Biochemistry
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Dehydration is catalyzed by glutamate-136 and aspartic acid-135 active site residues in Escherichia coli dTDP-glucose 4,6-dehydratase
2001
Gross, J.W.; Hegeman, A.D.; Gerratana, B.; Frey, P.A.
Biochemistry
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Probing catalysis by Escherichia coli dTDP-glucose-4,6-dehydratase: identification and preliminary characterization of functional amino acid residues at the active site
2001
Hegeman, A.D.; Gross, J.W.; Frey, P.A.
Biochemistry
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Mechanistic roles of Thr134, Tyr160, and Lys 164 in the reaction catalyzed by dTDP-glucose 4,6-dehydratase
2001
Gerratana, B.; Cleland, W.W.; Frey, P.A.
Biochemistry
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Concerted and stepwise dehydration mechanisms observed in wild-type and mutated Escherichia coli dTDP-glucose 4,6-dehydratase
2002
Hegeman, A.D.; Gross, J.W.; Frey, P.A.
Biochemistry
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High resolution X-ray structure of dTDP-glucose 4,6-dehydratase from Streptomyces venezuelae
2004
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Function of lysine-148 in dTDP-D-glucose 4,6-dehydratase from Streptomyces antibioticus Tue99
2002
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Expression of orf7(oxi III) as dTDP-glucose 4,6-dehydratase gene cloned from Streptomyces antibioticus Tu99 and biochemical characteristics of expressed protein
1999
Yoo, J.C.; Han, J.M.; Sohng, J.K.
J. Microbiol. Biotechnol.
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The crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Salmonella enterica serovar typhimurium, the second enzyme in the dTDP-l-rhamnose pathway
2001
Allard, S.T.; Giraud, M.F.; Whitfield, C.; Graninger, M.; Messner, P.; Naismith, J.H.
J. Mol. Biol.
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A bifunctional 3,5-epimerase/4-keto reductase for nucleotide-rhamnose synthesis in Arabidopsis
2004
Watt, G.; Leoff, C.; Harper, A.D.; Bar-Peled, M.
Plant Physiol.
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Characterization and investigation of substrate specificity of the sugar aminotransferase WecE from E. coli K12
2004
Hwang, B.Y.; Lee, H.J.; Yang, Y.H.; Joo, H.S.; Kim, B.G.
Chem. Biol.
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RmlC, a C3 and C5 carbohydrate epimerase, appears to operate via an intermediate with an unusual twist boat conformation
2007
Dong, C.; Major, L.L.; Srikannathasan, V.; Errey, J.C.; Giraud, M.F.; Lam, J.S.; Graninger, M.; Messner, P.; McNeil, M.R.; Field, R.A.; Whitfield, C.; Naismith, J.H.
J. Mol. Biol.
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Biochemical characterization of dTDP-D-Qui4N and dTDP-D-Qui4NAc biosynthetic pathways in Shigella dysenteriae type 7 and Escherichia coli O7
2007
Wang, Y.; Xu, Y.; Perepelov, A.V.; Qi, Y.; Knirel, Y.A.; Wang, L.; Feng, L.
J. Bacteriol.
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Identification of triazinoindol-benzimidazolones as nanomolar inhibitors of the Mycobacterium tuberculosis enzyme TDP-6-deoxy-D-xylo-4-hexopyranosid-4-ulose 3,5-epimerase (RmlC)
2010
Sivendran, S.; Jones, V.; Sun, D.; Wang, Y.; Grzegorzewicz, A.E.; Scherman, M.S.; Napper, A.D.; McCammon, J.A.; Lee, R.E.; Diamond, S.L.; McNeil, M.
Bioorg. Med. Chem.
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Spontaneous mutation results in lower cellulose production by a Gluconacetobacter xylinus strain from Kombucha
2010
Nguyen, V.; Flanagan, B.; Mikkelsen, D.; Ramirez, S.; Rivas, L.; Gidley, M.; Dykes, G.
Carbohydr. Polym.
80
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Characterization of TDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from the D-mycaminose biosynthetic pathway of Streptomyces fradiae: in vitro activity and substrate specificity studies
2007
Melançon, C.E. 3rd.; Hong, L.; White, J.A.; Liu, Y.N.; Liu, H.W.
Biochemistry
46
577-590
Molecular architecture of DesI: a key enzyme in the biosynthesis of desosamine
2007
Burgie, E.S.; Holden, H.M.
Biochemistry
46
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Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose in Aneurinibacillus thermoaerophilus L420-91T
2003
Pfoestl, A.; Hofinger, A.; Kosma, P.; Messner, P.
J. Biol. Chem.
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The X-ray structure of dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase
2007
Davis, M.L.; Thoden, J.B.; Holden, H.M.
J. Biol. Chem.
282
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Characterization of the TDP-D-ravidosamine biosynthetic pathway: one-pot enzymatic synthesis of TDP-D-ravidosamine from thymidine-5-phosphate and glucose-1-phosphate
2011
Kharel, M.K.; Lian, H.; Rohr, J.
Org. Biomol. Chem.
9
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Cloning, expression, and biological function of a dTDP-deoxyglucose epimerase (gerF) gene from Streptomyces sp. GERI-155
2004
Sohng, J.K.; Kim, H.J.; Nam, D.H.; Lim, D.O.; Han, J.M.; Lee, H.J.; Yoo, J.C.
Biotechnol. Lett.
26
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Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP
2007
Thuy, T.T.; Liou, K.; Oh, T.J.; Kim, D.H.; Nam, D.H.; Yoo, J.C.; Sohng, J.K.
Glycobiology
17
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Characterization of the dTDP-D-fucofuranose biosynthetic pathway in Escherichia coli O52
2008
Wang, Q.; Ding, P.; Perepelov, A.V.; Xu, Y.; Wang, Y.; Knirel, Y.A.; Wang, L.; Feng, L.
Mol. Microbiol.
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Exploration of two epimerase homologs in Streptomyces peucetius ATCC 27952
2013
Singh, B.; Oh, T.; Sohng, J.
Appl. Microbiol. Biotechnol.
97
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TDP-L-megosamine biosynthesis pathway elucidation and megalomicin a production in Escherichia coli
2010
Useglio, M.; Peiru, S.; Rodriguez, E.; Labadie, G.R.; Carney, J.R.; Gramajo, H.
Appl. Environ. Microbiol.
76
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Structure of EvaA: a paradigm for sugar 2,3-dehydratases
2013
Kubiak, R.L.; Thoden, J.B.; Holden, H.M.
Biochemistry
52
2078-2088
Characterization of SpnQ from the spinosyn biosynthetic pathway of Saccharopolyspora spinosa: Mechanistic and evolutionary implications for C-3 deoxygenation in deoxysugar biosynthesis
2006
Hong L, H.L.; Zhao Z, Z.Z.; Liu H.-W, L.H.
J. Am. Chem. Soc.
128
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Structure of the Bacillus anthracis dTDP-L-rhamnose-biosynthetic enzyme dTDP-4-dehydrorhamnose 3,5-epimerase (RfbC)
2017
Shornikov, A.; Tran, H.; Macias, J.; Halavaty, A.S.; Minasov, G.; Anderson, W.F.; Kuhn, M.L.
Acta Crystallogr. Sect. F
73
664-671
Identification of a dTDP-rhamnose biosynthetic pathway that oscillates with the molting cycle in Caenorhabditis elegans
2016
Feng, L.; Shou, Q.; Butcher, R.A.
Biochem. J.
473
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Bacterial sugar 3,4-ketoisomerases structural insight into product stereochemistry
2015
Thoden, J.; Vinogradov, E.; Gilbert, M.; Salinger, A.; Holden, H.
Biochemistry
54
4495-4506
The KL24 gene cluster and a genomic island encoding a Wzy polymerase contribute genes needed for synthesis of the K24 capsular polysaccharide by the multiply antibiotic resistant Acinetobacter baumannii isolate RCH51
2017
Kenyon, J.; Kasimova, A.; Shneider, M.; Shashkov, A.; Arbatsky, N.; Popova, A.; Miroshnikov, K.; Hall, R.; Knirel, Y.
Microbiology
163
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Haloferax volcanii N-glycosylation delineating the pathway of dTDP-rhamnose biosynthesis
2014
Kaminski, L.; Eichler, J.
PLoS ONE
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