Ligand 3-amino-5-hydroxybenzoate
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Basic Ligand Information
C7H7NO3
3-amino-5-hydroxybenzoate
QPEJHSFTZVMSJH-UHFFFAOYSA-N
Related pathways
MetaCyc
3-amino-5-hydroxybenzoate biosynthesis, ansamitocin P biosynthesis, ansatrienin biosynthesis, chaxamycin biosynthesis, diazepinomicin biosynthesis
, mitomycin biosynthesis, naphthomycin biosynthesis, rifamycin B biosynthesis, streptovaricin biosynthesis
more
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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ATP + 3-amino-5-hydroxybenzoate + a holo-[acyl-carrier protein] = 3-amino-5-hydroxybenzoyl-[acyl-carrier protein] + AMP + diphosphate
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Substrate in Enzyme-catalyzed Reactions (1 result)
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ATP + 3-amino-5-hydroxybenzoate + a holo-[acyl-carrier protein] = 3-amino-5-hydroxybenzoyl-[acyl-carrier protein] + AMP + diphosphate
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Product in Enzyme-catalyzed Reactions (1 result)
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5-amino-5-deoxy-3-dehydroshikimate = 3-amino-5-hydroxybenzoate + H2O
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Enzyme Kinetic Parameters
References & Links
Literature References (2)
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The loading module of rifamycin synthetase is an adenylation - Thiolation didomain with substrate tolerance for substituted benzoates
2001
Admiraal, S.; Walsh, C.; Khosla, C.
Biochemistry
40
6116-6123
The loading and initial elongation modules of rifamycin synthetase collaborate to produce mixed aryl ketide products
2002
Admiraal, S.; Khosla, C.; Walsh, C.
Biochemistry
41
5313-5324
Links to other databases for 3-amino-5-hydroxybenzoate