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BRENDA support

Ligand 7,8-dihydroneopterin 3'-phosphate

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Basic Ligand Information

Molecular Structure
Picture of 7,8-dihydroneopterin 3'-phosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C9H14N5O7P
7,8-dihydroneopterin 3'-phosphate
PLSQMGZYOGSOCE-XINAWCOVSA-N
Synonyms:
7,8-dihydro-D-neopterin 3'-phosphate, dihydroneopterin 3'-phosphate, dihydroneopterin phosphate
Pathway Source
Pathways
BRENDA
6-hydroxymethyl-dihydropterin diphosphate biosynthesis
KEGG
Biosynthesis of cofactors, Folate biosynthesis
MetaCyc
6-hydroxymethyl-dihydropterin diphosphate biosynthesis I, 6-hydroxymethyl-dihydropterin diphosphate biosynthesis II (Methanocaldococcus), 6-hydroxymethyl-dihydropterin diphosphate biosynthesis III (Chlamydia), 6-hydroxymethyl-dihydropterin diphosphate biosynthesis V (Pyrococcus)


Show all pahtways known for Show all BRENDA pathways known for 7,8-dihydroneopterin 3'-phosphate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

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EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
7,8-dihydroneopterin 3'-phosphate = 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde phosphate
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (4 results)

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EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
7,8-dihydroneopterin 2',3'-cyclic phosphate + H2O = 7,8-dihydroneopterin 3'-phosphate
show the reaction diagram
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7,8-dihydroneopterin 3'-triphosphate + H2O = 7,8-dihydroneopterin 3'-phosphate + diphosphate
show the reaction diagram
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2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one = 7,8-dihydroneopterin 3'-phosphate + H2O
show the reaction diagram
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2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one = 7,8-dihydroneopterin 3'-phosphate + H2O
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (1 result)

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EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
7,8-dihydroneopterin 3'-phosphate = 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde phosphate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (4 results)

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EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
7,8-dihydroneopterin 2',3'-cyclic phosphate + H2O = 7,8-dihydroneopterin 3'-phosphate
show the reaction diagram
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7,8-dihydroneopterin 3'-triphosphate + H2O = 7,8-dihydroneopterin 3'-phosphate + diphosphate
show the reaction diagram
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2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one = 7,8-dihydroneopterin 3'-phosphate + H2O
show the reaction diagram
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2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one = 7,8-dihydroneopterin 3'-phosphate + H2O
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

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EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
0.074 mM, 21% inhibition; inhibits 21% at a concentration of 0.074 mM, when the substrate is present at 0.032 mM
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Enzyme Kinetic Parameters

References & Links

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Links to other databases for 7,8-dihydroneopterin 3'-phosphate

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ChEBI
PubChem
ChEBI
PubChem