Ligand 1,2-Butanediol

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Basic Ligand Information

Molecular Structure
Picture of 1,2-Butanediol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H10O2
1,2-Butanediol
SVPYTKQVGNMIBM-SDPXSBNPSA-N
Synonyms:
(R,S)-1,2-butandiol, 2-hydroxy-n-butanol, butane-1,2-diol, DL-1,2-Butanediol

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (28 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1,2-butanediol + NAD+ = ? + NADH + H+
show the reaction diagram
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1,2-butanediol + NADP+ = 1-hydroxybutan-2-one + NADPH
show the reaction diagram
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1,2-butanediol + NAD+ = ? + NADH + H+
show the reaction diagram
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1,2-butanediol + NAD+ = 1-hydroxybutan-2-one + NADH
show the reaction diagram
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1,2-butanediol + NAD+ = ? + NADH
show the reaction diagram
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butane-1,2-diol + NADP+ = ? + NADPH
show the reaction diagram
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1,2-butanediol + NAD+ = ? + NADH
show the reaction diagram
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1,2-butanediol + ferricytochrome c = ?
show the reaction diagram
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1,2-butanediol + O2 = 1,2-butanedione + H2O2
show the reaction diagram
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1,2-butanediol + O2 = ?
show the reaction diagram
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1,2-butanediol + O2 = ?
show the reaction diagram
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1,2-butanediol + pyrroloquinoline quinone = ?
show the reaction diagram
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1,2-butanediol + ferricyanide = 2-hydroxybutanal + ferrocyanide
show the reaction diagram
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butane-1,2-diol + NAD+ = but-1-ene-1,2-diol + NADH
show the reaction diagram
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di-N-acetylchitobiose + 1,2-butanediol = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-hydroxy-2-butanone + NADH + H+ = butane-1,2-diol + NAD+
show the reaction diagram
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1,2-epoxybutane + H2O = 2-hydroxy-n-butanol
show the reaction diagram
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-

Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
activates
-
isoform AC6 shows about 37% stimulation of activity with 100 mM 1,2-butanediol, isoform AC7 shows about 38% stimulation of activity with 100 mM 1,2-butanediol, isoform AC9 shows about 32% stimulation of activity with 100 mM 1,2-butanediol
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (5 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.29
-
pH 7.5, 30°C

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
150
-
pH 7.5, 30°C
2.5
-
pH 8.0, 37°C

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.97
-
pH 8.0, 37°C

References & Links

Links to other databases for 1,2-Butanediol

ChEBI
PubChem
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PubChem