Ligand 2-Oxoglutaramate

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Basic Ligand Information

Molecular Structure
Picture of 2-Oxoglutaramate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H7NO4
2-Oxoglutaramate
COJBGNAUUSNXHX-UHFFFAOYSA-N
Synonyms:
2,5-dioxo-5-aminopentanoate, 2-ketoglutaramate, 2-oxo-4-carbamoylbutanoic acid, 2-oxo-glutaramate, 2-oxoglutamine, 2-oxoglutaric acid 5-amide, 4-Carbamoyl-2-oxobutanoate, 5-amino-2,5-dioxopentanoate, 5-amino-2,5-dioxopentanoic acid, alpha-ketoglutaramate


Show all pahtways known for Show all BRENDA pathways known for 2-Oxoglutaramate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-oxoglutaramate + H2O = 2-oxoglutarate + NH3
show the reaction diagram
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alpha-ketoglutaramate + H2O = alpha-ketoglutarate + NH3
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-glutamine + H2O + O2 = 2-oxo-4-carbamoylbutanoic acid + NH3 + H2O2
show the reaction diagram
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L-glutamine + 2-deoxy-scyllo-inosose = 2-oxoglutaramate + 2-deoxy-scyllo-inosamine
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L-glutamine + 3-amino-2,3-dideoxy-scyllo-inosose = 2-oxoglutaramate + 2-deoxystreptamine
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L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine
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L-glutamine + phenylpyruvate = 2-oxoglutaramate + L-phenylalanine
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Substrate in Enzyme-catalyzed Reactions (29 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-oxoglutaramate + H2O = ?
show the reaction diagram
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2-oxo-glutaramate + H2O = ?
show the reaction diagram
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alpha-ketoglutaramate + H2O = alpha-ketoglutarate + NH3
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (76 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-glutamine + H2O + NAD+ = 2-oxoglutaramate + NH3 + NADH
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D-glutamine + oxidized 2,6-dichloroindophenol + H2O = 4-carbamoyl-2-oxobutanoate + NH3 + reduced 2,6-dichloroindophenol
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L-glutamine + 2-deoxy-scyllo-inosose = 2-oxoglutaramate + 2-deoxy-scyllo-inosamine
show the reaction diagram
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L-glutamine + 3-amino-2,3-dideoxy-scyllo-inosose = 2-oxoglutaramate + 2-deoxystreptamine
show the reaction diagram
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phenylpyruvate + L-glutamine = L-phenylalanine + 2-oxoglutaramate
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L-glutamate + glyoxylate = 2-oxoglutaramate + glycine
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dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamine = dTDP-4-amino-4,6-dideoxy-D-galactose + 2-oxoglutamine
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L-glutamine + 2-oxoglutarate = 2,5-dioxo-5-aminopentanoate + L-glutamate
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L-glutamine + 4,5-dioxopentanoate = 5-aminolevulinate + 2-oxoglutaramate
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L-glutamine + indole pyruvate = 2-oxoglutamine + L-tryptophan
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L-glutamine + phenylpyruvate = 5-amino-2,5-dioxopentanoic acid + L-phenylalanine
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dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamine = dTDP-4-amino-4,6-dideoxy-D-galactose + 2-oxoglutaramate
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glutamine + glyoxylate = 4-carbamoyl-2-oxobutanoate + glycine
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L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine
show the reaction diagram
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3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamine = L-histidinol phosphate + 4-carbamoyl-2-oxobutanoate
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (3 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
194
-
pH 7.1, 30 °C
17.5
-
pH 8.5, 30°C
17.5
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pH 8.5, 30°C

KM Value (14 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
50
-
pH 8.4, 37ºC
6.3
-
pH 7.1, 30 °C
0.195
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pH 8.5, 30°C

References & Links

Links to other databases for 2-Oxoglutaramate

ChEBI
PubChem
ChEBI
PubChem