Ligand geranic acid

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Basic Ligand Information

Molecular Structure
Picture of geranic acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H16O2
geranic acid
ZHYZQXUYZJNEHD-VQHVLOKHSA-N
Synonyms:
(2E)-3,7-dimethylocta-2,6-dienoic acid, (2E)-geranoic acid, 3,7-dimethyl-2,6-octadienoate, geranate, trans-geranic acid

Roles as Enzyme Ligand

Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
citral + NAD+ + H2O = (2E)-3,7-dimethylocta-2,6-dienoic acid + NADH
show the reaction diagram
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citral + NAD+ + H2O = (2E)-3,7-dimethylocta-2,6-dienoic acid + NADH + H+
show the reaction diagram
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geranial + H2O + NAD+ = geranate + NADH + H+
show the reaction diagram
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citral + NAD+ + H2O = 3,7-dimethyl-2,6-octadienoate + NADH + 2 H+
show the reaction diagram
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citral + H2O + O2 = (2E)-3,7-dimethylocta-2,6-dienoic acid + H2O2
show the reaction diagram
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3,7-dimethyl-2,6-octadienal + H2O + O2 = 3,7-dimethyl-2,6-octadienoate + ?
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
resembles the proposed enolate intermediate and acts non-competitively, geranic acid binding pocket and binding structure, overview

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.004
-
pH 7.0, 25°C, recombinant wild-type enzyme

IC50 Value (2 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE

References & Links

Links to other databases for geranic acid

ChEBI
PubChem
ChEBI
PubChem