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BRENDA support

Ligand sulfur

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Basic Ligand Information

Molecular Structure
Picture of sulfur (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
S
sulfur
NINIDFKCEFEMDL-UHFFFAOYSA-N
Synonyms:
elemental sulfur, S, sulfane sulfur, [S]


Show all pahtways known for Show all BRENDA pathways known for sulfur

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
sulfur = H2S
show the reaction diagram
-
sulfur + NAD(P)H + H+ = hydrogen sulfide + NAD(P)+
show the reaction diagram
-
S-adenosyl-L-methionine + sulfur = S-adenosyl-L-homocysteine + ?
show the reaction diagram
-
protein N6-(octanoyl)lysine + sulfur + S-adenosyl-L-methionine = protein N6-(lipoyl)lysine + L-methionine + 5'-deoxyadenosine
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
hydrogen sulfide + 2 ferricytochrome c = sulfur + 2 ferrocytochrome c + 2 H+
show the reaction diagram
-
L-cysteine = L-alanine + sulfur
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (37 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S + NADPH = H2S + NADP+
show the reaction diagram
-
H2 + sulfur = H2S
show the reaction diagram
-
H2 + S = H2S
show the reaction diagram
-
sulfur + reduced benzyl viologen + H+ = sulfide + oxidized benzyl viologen
show the reaction diagram
-
sulfur + reduced methyl viologen + H2O = H2S + oxidized methyl viologen
show the reaction diagram
-
S-adenosyl-L-methionine + sulfur = S-adenosyl-L-homocysteine + ?
show the reaction diagram
-
sulfane sulfur + cyanide = thiocyanate + ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (45 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
fenthion + NADPH + H+ + O2 = fenthion-oxon + sulfur + NADP+ + H2O
show the reaction diagram
-
sulfide + O2 = sulfur + H2O2
show the reaction diagram
-
L-cysteine = L-alanine + sulfur
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
sulfide, elemental sulfur, elemental selenium or hydroxylamine required in catalytic amount, inhibition when added over a critical concentration (with the exception of hydroxylamine)
-
elemental sulfur, reversible by dithiothreitol, muscle, not liver isozyme
-

Metals and Ions (11 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
contains acid-labile sulfur, iron-sulfur centres
-
iron-sulfur centre
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.2
-
-

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0013
-
at pH 6.0 and 30°C

References & Links

Links to other databases for sulfur

ChEBI
PubChem
ChEBI
PubChem