Ligand 2-deoxy-2-fluoro-D-glucose

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Basic Ligand Information

Molecular Structure
Picture of 2-deoxy-2-fluoro-D-glucose (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H11FO5
2-deoxy-2-fluoro-D-glucose
ZCXUVYAZINUVJD-WVQXMEFOSA-N
Synonyms:
2-fluoro-2-deoxy-D-glucose, 2-fluoro-D-glucose

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-deoxy-2-fluoro-D-glucose + O2 = 2-deoxy-3-dehydro-D-glucose + H2O2
show the reaction diagram
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alpha-D-glucose 1-phosphate + 2-deoxy-2-fluoro-D-glucose = ?
show the reaction diagram
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2-deoxy-2-fluoro-D-glucose + alpha-D-mannose 1-phosphate = 4-O-beta-D-mannopyranosyl-2-deoxy-2-fluoro-D-glucopyranose + phosphate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (3 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.89
-
-
5.71
-
apparent value, pH 6.5, 37°C, synthetic reaction, cosubstrate alpha-D-mannose 1-phosphate

KM Value (6 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
17.2
-
-
48.7
-
apparent value, pH 6.5, 37°C, synthetic reaction, cosubstrate alpha-D-mannose 1-phosphate

References & Links

Links to other databases for 2-deoxy-2-fluoro-D-glucose

ChEBI
PubChem
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PubChem