Ligand (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate

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Basic Ligand Information

Molecular Structure
Picture of (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C7H9NO4
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
CXMBCXQHOXUCEO-BYPYZUCNSA-N
Synonyms:
(2S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylic acid, (S)-2,3,4,5-tetrahydrodipicolinate, L-2,3,4,5-tetrahydrodipicolinate


Show all pahtways known for Show all BRENDA pathways known for (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ = (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O
show the reaction diagram
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LL-2,6-diaminoheptanedioate + 2-oxoglutarate = (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + L-glutamate + H2O
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + L-glutamate + H2O = LL-2,6-diaminoheptanedioate + 2-oxoglutarate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
LL-2,6-diaminoheptanedioate + 2-oxoglutarate = (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + L-glutamate + H2O
show the reaction diagram
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Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
7
-
pH 7.5, 22°C

References & Links

Links to other databases for (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate

ChEBI
PubChem
ChEBI
PubChem