Ligand sodium sulfite

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Basic Ligand Information

Molecular Structure
Picture of sodium sulfite (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
H3NaO3S
sodium sulfite
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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
sodium sulfite + H2O + A = NaSO42- + AH2
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
enhances hydrolysis of eggshell-membrane
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addition of sodium sulfite stimulates the production of L-threo-3,4-dihydroxyphenylserine without affecting the diastereoselectivity ratio, especially at 50 mM
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Inhibitor in Enzyme-catalyzed Reactions (15 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
uncompetitive vs. NAD+ and acetoacetate, competitive vs. beta-hydroxybutyrate
-
reduces FMN
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46.2% inhibition at 0.1 mM
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a high initial concentration of sodium sulfite decreases dramatically the enzyme expression
-
0.1 mM, presence of 200 mM NaCl, 45% residual activity
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3 mM, 94% inhibition
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about 60% residual activity at 5 mM
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Enzyme Kinetic Parameters

IC50 Value (2 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE

References & Links

Links to other databases for sodium sulfite

ChEBI
PubChem
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PubChem