We're sorry, but BRENDA doesn't work properly without JavaScript. Please make sure you have JavaScript enabled in your browser settings.
Ligand delta-tocotrienol Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C2 7 H4 0 O2
delta-tocotrienol
ODADKLYLWWCHNB-LDYBVBFYSA-N
Show all BRENDA pathways known for delta-tocotrienol
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
delta-tocotrienol + [reduced NADPH-hemoprotein reductase] + O2 = ?
-
Inhibitor in Enzyme-catalyzed Reactions (2 results)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
competitive, compound decreases leukotriene B4 from stimulated neutrophil-like cells without affecting translocation of 5-Lox from cytosol to the nucleus. Compound additionally inhibits cyclooxygenases Cox-1 and Cox-2
-
inhibits isoform Cox-1 and suppresses Cox-1 mediated formation of thromboxane in collagen-stimulated rat's platelets
-
Enzyme Kinetic Parameters
Ki Value (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.0022
-
pH not specified in the publication, temperature not specified in the publication
References & Links Literature References (2)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Common variants of cytochrome P450 4F2 exhibit altered vitamin E-omega-hydroxylase specific activity
2010
Bardowell, S.A.; Stec, D.E.; Parker, R.S.
J. Nutr.
140
1901-1906
Different forms of vitamin E and metabolite 13-carboxychromanols inhibit cyclooxygenase-1 and its catalyzed thromboxane in platelets, and tocotrienols and 13-carboxychromanols are competitive inhibitors of 5-lipoxygenase
2022
Park, N.Y.; Im, S.; Jiang, Q.
J. Nutr. Biochem.
100
108884
Links to other databases for delta-tocotrienol