Ligand 4-(glutamylamino) butanoate
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Basic Ligand Information
Molecular Structure

C9H16N2O5
4-(glutamylamino) butanoate
MKYPKZSGLSOGLL-LURJTMIESA-N
4-(gamma-glutamylamino)butanoate, 4-(gamma-L-glutamylamino)butanoate, 4-(L-gamma-glutamylamino)butanoate, 5-L-glutamylaminobutyrate, gamma-(glutamylamino)butanoate, gamma-L-Glu-gamma-aminobutyrate, gamma-L-Glu-L-gamma-aminobutyrate, N-(3-carboxypropyl)-L-glutamine
Show all BRENDA pathways known for 4-(glutamylamino) butanoate
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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4-(gamma-glutamylamino)butanoate + H2O = 4-aminobutanoate + L-glutamate
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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gamma-glutamyl-gamma-aminobutyraldehyde + NAD+ + H2O = 4-(glutamylamino) butanoate + NADH + 2 H+
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Substrate in Enzyme-catalyzed Reactions (2 results)
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4-(gamma-glutamylamino)butanoate + H2O = 4-aminobutanoate + L-glutamate
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gamma-(glutamylamino)butanoate + H2O = gamma-aminobutanoate + L-glutamate
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Product in Enzyme-catalyzed Reactions (3 results)
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4-(gamma-L-glutamylamino)butanal + NAD+ + H2O = 4-(gamma-L-glutamylamino)butanoate + NADH + H+
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gamma-glutamyl-gamma-aminobutyraldehyde + NAD+ + H2O = 4-(glutamylamino) butanoate + NADH + 2 H+
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ATP + L-Glu + gamma-aminobutyrate = ADP + phosphate + gamma-L-Glu-gamma-aminobutyrate
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Enzyme Kinetic Parameters
References & Links
Literature References (2)
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Substrate binding determinants of Trypanosoma brucei gamma-glutamylcysteine synthetase
2002
Abbott, J.J.; Ford, J.L.; Phillips, M.A.
Biochemistry
41
2741-2750
gamma-Glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12
2006
Kurihara, S.; Oda, S.; Kumagai, H.; Suzuki, H.
FEMS Microbiol. Lett.
256
318-323
Links to other databases for 4-(glutamylamino) butanoate