Ligand C18-ceramide

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Basic Ligand Information

Molecular Structure
Picture of C18-ceramide (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C36H71NO3
C18-ceramide
VODZWWMEJITOND-NXCSZAMKSA-N
Synonyms:
an N-(stearoyl)-sphingoid base, C18:0-ceramide, D-eythro-C18:0 ceramide, N-(stearoyl)-ceramide, N-stearoylceramide, octadecanoyl-ceramide, stearoyl ceramide, stearoylsphingosine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
C18:0-ceramide + H2O = stearate + sphingosine
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
stearoyl-CoA + a sphingoid base = an N-(stearoyl)-sphingoid base + CoA
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
stearoyl-CoA + a sphingoid base = an N-(stearoyl)-sphingoid base + CoA
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stearoyl-CoA + a sphingoid base = an N-(stearoyl)-sphingoid base + CoA
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
mtCDase, competitive inhibition, IC50: 0.62 mol%
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Enzyme Kinetic Parameters

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for C18-ceramide

ChEBI
PubChem
ChEBI
PubChem