cytochrome c also inhibits the reaction and half-inhibition is found in the presence of 17 microM cytochrome c. The addition of cytochrome c to the reaction mixture containing 2-nitropropane and 2-nitropropane dioxygenase causes an increase in absorbance at 550 nm indicating the reduction of cytochrome c

639224

1.14.13.25

one of three protein components is a soluble CO-binding cytochrome c

438921

the gamma-subunit of the alpha3beta3gamma3 enzyme is cytochrome c1

696547

1.15.1.2

artificial electron carrier

a quinohaemoprotein, contains one covalently bound haem per molecule, the C-terminal domain contains characteristics of a cytochrome c. The heme accepts only one electron, for the two-electron dehydrogenase reaction, a second electron acceptor must be present (pyrroloquinoline quinone)

in its purest state the enzyme contains one molecule of cytochrome co-ordinated by two histidine side chains in the oxidized state

713264, 746068, 746093, 746491, 745635, 746414, 746064

741908, 742316, 741932, 742802

742384, 741677, 742753, 742390, 741924

in a cytochrome bc1 complex

multiheme

presence of a cytochrome that may be an intermediary hydrogen carrier involved in reducing systems for sulfate and other sulfur compounds

740639

1.8.2.6

the cytochrome c motifs of subunit SoxD are buried in the protein core

octaheme cytochrome

Activator in Enzyme-catalyzed Reactions (9 results)

top print hide

1.1.5.3

role of cyt c in activation of glycerol-3-phosphate and succinate oxidation in frozenthawed mitochondria

maximal activation of hydrolysis of phosphatidylinositol 4,5-diphosphate at 0.0125 mg/ml

135136

3.4.22.56

4 entries

Inhibitor in Enzyme-catalyzed Reactions (58 results)

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1.1.99.14

inhibits rate of phenazine methosulfate stimulated dichlorophenolindophenol reduction

substrate inhibition

95% inhibition at 0.05 mM

50% inhibition at 0.001 mM

32.9% residual activity at 0.1 mM

724615

1.14.14.127

inhibition by oxidized cytochrome c, 20 microM, 52.4% residual activity

731740

1.14.14.135

0.01 mM: 25% inhibition, 0.025 mM: 64% inhibition, 0.05 mM: 85% inhibition

654324

1.14.14.136

0.01 mM, 46% inhibition

72% inhibition at 0.5 nM

673425

1.14.14.142

70% inhibition at 10 mM

complete inhibition at 0.1 mM, 0.003 mM

285439

1.14.14.174

0.01 mM, 96% inhibition

706368

1.14.14.176

0.4 mM, 50% inhibition

strong

less than 0.01 mM, 50% inhibition

639288

1.14.14.81

0.05 mM, complete inhibition

657026

1.14.14.82

439002, 439004, 439010

1.14.14.85

0.01 mM, 44.9% inhibition, 0.1 mM, 59.6% inhibition

440296

1.14.14.88

0.01 mM reduces activity to 4%, 0.1 mM reduces activity to 1%

285318

1.14.14.89

0.01 mM cytochrome c reduces activity to 14%, 0.1 mM cytochrome c reduces activity to 4%

285318

1.14.14.91

hydroxylase activity with NADPH is strongly inhibited, activity with NADH is less susceptible

97% inhibition at 0.1 mM

716587

1.14.14.96

76% inhibition at 0.1 mM

strong

1 mM, 78% inhibition of recombinant nicotine demethylase activity in yeast microsomes

700634

1.14.15.24

addition of cytochrome c to the incubation medium inhibits hydroxylase activity

partial inhibition

microsomal-bound enzyme

above 0.15 mM

inhibition of O2 consumption

393014

3.4.22.62

enzyme activity is inhibited in both normoxic and hypoxic groups. The IC50 increases 1.5fold following hypoxia, suggesting a hypoxia-induced modification of the cytochrome binding site. 70% inhibition by 0.003 mM

666456