Ligand 8-oxo-GTP

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Basic Ligand Information

Molecular Structure
Picture of 8-oxo-GTP (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H16N5O15P3
8-oxo-GTP
JCHLKIQZUXYLPW-RUVBSYQFSA-N
Synonyms:
8-oxoguanosine triphosphate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
8-oxo-GTP + H2O = 8-oxo-GMP + diphosphate
show the reaction diagram
-
8-oxo-GTP + H2O = 8-oxo-GMP + diphosphate
show the reaction diagram
-
8-oxo-GTP + H2O = 8-oxo-GDP + phosphate
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
8-oxoguanosine triphosphate + L-fucose 1-phosphate = diphosphate + (8-oxoguanosine diphosphate)-L-fucose
show the reaction diagram
-
8-oxo-GTP + H2O = 8-oxo-GMP + diphosphate
show the reaction diagram
-
8-oxo-GTP + H2O = 8-oxo-GMP + diphosphate
show the reaction diagram
-
8-oxo-GTP + H2O = 8-oxo-GDP + phosphate
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
2.6
-
pH 7.0, 37°C
2.6
-
pH 8.0, 30°C

KM Value (5 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0636
-
pH 7.0, 37°C
0.21
-
-
0.00026
-
pH 8.0, 30°C

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

IC50 Value (2 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE

References & Links

Links to other databases for 8-oxo-GTP

ChEBI
PubChem
-
PubChem