Ligand Phe-Phe

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Basic Ligand Information

Molecular Structure
Picture of Phe-Phe (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C18H20N2O3
Phe-Phe
GKZIWHRNKRBEOH-HOTGVXAUSA-N
Synonyms:
L-Phe-L-Phe, L-phenylalanyl-L-phenylalanine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Phe-Phe + H2O = Phe + Phe
show the reaction diagram
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Phe-Phe + H2O = Phe + Phe
show the reaction diagram
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L-Phe-L-Phe + H2O = L-Phe + L-Phe
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Phe-Phe-tRNA + H2O = Phe-Phe + tRNA
show the reaction diagram
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L-phenylalanine ethyl ester + L-phenylalanine + H2O = L-Phe-L-Phe + cyclo(L-phenylalanine-L-phenylalanine) + L-Phe-L-Phe ethyl ester
show the reaction diagram
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PDETYFF + H2O = PDETY + L-Phe-L-Phe
show the reaction diagram
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Arg-Gly-Phe-Phe + H2O = Arg-Gly + Phe-Phe
show the reaction diagram
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3-(2-furyl)acryloyl-glycyl-L-phenylalanyl-L-phenylalanine + H2O = L-phenylalanyl-L-phenylalanine + 3-(2-furyl)acryloyl-glycine
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
in the absence of dipeptides, transporter shows proton-dependent leak currents that are inhibited by Phe-Ala, Trp-Ala, and Phe-Phe. Phe-Ala reduces leak currents by binding to the substrate-binding site with a high apparent affinity
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
158
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KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
2.1
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Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.5
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References & Links

Links to other databases for Phe-Phe

ChEBI
PubChem
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PubChem