Ligand Salicin

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Basic Ligand Information

Molecular Structure
Picture of Salicin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C13H18O7
Salicin
NGFMICBWJRZIBI-UJPOAAIJSA-N
Synonyms:
(2-hydroxymethylphenyl)-beta-D-glucopyranoside, 2-(Hydroxymethyl)phenyl-beta-D-glucopyranoside, 2-(hydroxymethyl)phenyl beta-D-glucopyranoside, 2-hydroxymethylphenyl-beta-D-glucopyranoside

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(2-hydroxymethylphenyl)-beta-D-glucopyranoside + H2O = 2-hydroxymethylphenol + beta-D-glucose
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDPglucose + salicyl alcohol = UDP + salicin
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (65 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
salicin + acceptor = ?
show the reaction diagram
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2-hydroxymethylphenyl-beta-D-glucopyranoside + acceptor = ?
show the reaction diagram
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salicin + alpha-D-glucose 1-phosphate = 1,3-beta-D-glucosylsalicin + phosphate
show the reaction diagram
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alpha-D-glucose 1-phosphate + salicin = ?
show the reaction diagram
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sucrose + salicin = ?
show the reaction diagram
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sucrose + salicin = ?
show the reaction diagram
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ATP + salicin = ADP + salicin 6-phosphate
show the reaction diagram
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salicin + H2O = D-glucose + 2-(hydroxymethyl)phenol
show the reaction diagram
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salicin + H2O = ?
show the reaction diagram
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salicin + H2O = D-glucose + salicyl alcohol
show the reaction diagram
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salicin + H2O = ?
show the reaction diagram
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2-nitrophenyl beta-D-galactopyranoside + salicin = 2-(hydroxymethyl)phenyl beta-D-galactopyranosyl-(1->6)-beta-D-glucopyranoside + 2-nitrophenol
show the reaction diagram
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(2-hydroxymethylphenyl)-beta-D-glucopyranoside + H2O = 2-hydroxymethylphenol + beta-D-glucose
show the reaction diagram
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(2-hydroxymethylphenyl)-beta-D-glucopyranoside + H2O = 2-hydroxymethylphenol + beta-D-glucose
show the reaction diagram
-
salicin + H2O = ?
show the reaction diagram
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(2-hydroxymethylphenyl)-beta-D-glucopyranoside + H2O = 2-hydroxymethylphenol + beta-D-glucose
show the reaction diagram
-
salicin + H2O = ?
show the reaction diagram
-
salicin + H2O = ?
show the reaction diagram
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salicin + H2O = beta-D-glucose + 2-(hydroxymethyl)phenol
show the reaction diagram
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salicin + H2O = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDPglucose + salicyl alcohol = UDP + salicin
show the reaction diagram
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UDP-glucose + saligenin = UDP + 2-(hydroxymethyl)phenyl beta-D-glucopyranoside
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
stimulate
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activation
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Inhibitor in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
inhibitor of isoform EIICBAGlc2
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0.1 M, 97% inhibition of beta-galactoside hydrolysis, 92% inhibition of beta-glucoside hydrolysis
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3D Structure of Enzyme-Ligand-Complex (PDB) (10 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (9 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
44
-
pH 6.0, 90°C

KM Value (29 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.045
-
pH 6.5, 30°C
1.96
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pH 6.0, 90°C

Ki Value (5 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
3.4
-
-
0.0179
-
solubilized isoform EIICBAGlc2, at pH 7.5 and 37°C
0.81
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pH 6.5, 50°C

References & Links

Links to other databases for Salicin

ChEBI
PubChem
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PubChem