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Ligand phenyl acetate

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Natural Substrate (2 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

3.1.1.2

phenyl acetate + H2O = ?

35206, 35195, 35201, 35204, 35199, 35203, 35193, 35200

-

3.1.1.2

phenyl acetate + H2O = phenol + acetate

750292

-

3.1.1.2

2 entries

Substrate in Enzyme-catalyzed Reactions (12 results)

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Show Substrate (12 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

3.1.1.1

phenyl acetate + H2O = phenol + acetate

171008, 171001, 171000, 171010, 171011, 729255, 171026, 171017, 652627, 653767, 679382, 721900

4c01, 3D-view

3.1.1.17

phenyl acetate + H2O = ?

691230

-

3.1.1.2

phenyl acetate + H2O = ?

35206, 35195, 35201, 35204, 35199, 35203, 35193, 35200

-

3.1.1.2

phenyl acetate + H2O = phenol + acetate

35207, 35212, 35215, 35220, 646527, 650864, 652704, 665028, 692695, 693321, 702421, 703470, 707155, 707214, 708095, 709261, 709755, 714112, 714759, 714893, 714895, 715735, 715738, 729339, 749628, 749762, 749840, 750340, 750345, 750428, 750482, 750483, 750484, 750511, 750758, 752150, 752173, 35217, 646521, 714002, 714637, 666183, 729013, 35204, 750166, 693586, 646535, 652628, 690390, 692124, 692245, 646528, 664064, 664111, 664184, 664885, 665745, 678376, 678464, 679262, 679293, 679306, 679634, 681055, 681730, 690419, 691863, 691873, 692541, 692732, 693354, 693357, 694871, 695051, 695124, 695193, 729324, 730898, 663985, 670788, 649767, 690676, 691536, 692889, 729510, 729864, 750292, 651605, 665960, 691855, 691851, 650953, 35213, 694369, 677411, 677297, 691230, 646509, 713914

-

3.1.1.2

2 entries

3.1.1.25

phenyl acetate + H2O = ?

670788

-

3.1.1.55

phenyl acetate + H2O = phenol + acetate

646021

-

3.1.1.6

phenyl acetate + H2O = phenol + acetate

652394, 696095

-

3.1.1.73

phenyl acetate + H2O = phenol + acetate

729036

-

3.1.1.8

phenyl acetate + H2O = phenol + acetate

714817

-

3.1.8.1

phenyl acetate + H2O = phenol + acetate

652704, 663985, 664620, 666714, 749628, 749610

-

3.1.8.2

phenyl acetate + H2O = phenol + acetate

664937, 749628

-

6.2.1.75

ATP + phenyl acetate + CoA = ?

764580

-

Product in Enzyme-catalyzed Reactions (3 results)

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Show Product (3 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.14.13.84

acetophenone + NADPH + H+ + O2 = phenyl acetate + NADP+ + H2O

0, 649387, 651670, 644553

-

1.2.1.8

phenyl acetaldehyde + NAD+ + H2O = phenyl acetate + NADH + H+

0

-

1.2.1.8

phenyl acetaldehyde + NADP+ + H2O = phenyl acetate + NADPH + H+

0

-

1.2.1.8

2 entries

Inhibitor in Enzyme-catalyzed Reactions (3 results)

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Show Inhibitors (3 entries)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

3.1.1.2

-

35212

-

3.1.1.2

inhibits hydrolysis of 4-nitrophenyl acetate

35215

-

3.1.1.2

2 entries

3.1.8.1

-

664885

-

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

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Show 3D Structure of Enzyme-Ligand-Complex (PDB) (1 entry)

EC NUMBER

ENZYME 3D STRUCTURE

3.1.1.1

4c01, 3D-view

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (42 results)

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Show Turnover Number (42 entries)

EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

3.1.1.1

30

-

in 2.5 mM Bicine buffer, pH 8.3, at 30°C

729255

3.1.1.1

156

-

-

171011

3.1.1.1

300

-

-

171010

3.1.1.1

380

-

-

171010

3.1.1.1

550

-

pH 8.0, 22°C

679382

3.1.1.2

0.35

-

pH 8.3, 25°C

729510

3.1.1.2

7.4

-

pH 8.0, mutant enzyme H115Q/H134Q

665745

3.1.1.2

10.5

-

pH 8.0, mutant enzyme H115Q

665745

3.1.1.2

102

-

immobilized cross-linked enzyme aggregate, at pH 7.0 and 25°C

750166

3.1.1.2

185

-

pH 8.0, mutant enzyme H134Q

665745

3.1.1.2

231

-

pH 7.0, 25°

729864

3.1.1.2

454

-

pH 8.0, 10°C

729339

3.1.1.2

503

-

pH 8.0, 15°C

729339

3.1.1.2

509

-

pH 8.3, activity buffer

664064

3.1.1.2

521

-

recombinant wild type enzyme, in 100 mM sodium phosphate buffer (pH 7.0), at 60°C

692889

3.1.1.2

525.8

-

mutant H115W, pH 8.0, 25°C

729324

3.1.1.2

645

-

pH 8.3, activity buffer with 0.1% tergitol

664064

3.1.1.2

659

-

pH 8.0, 20°C

729339

3.1.1.2

685

-

pH 8.3, activity buffer with 0.01 mM apolipoprotein apoA-I rHDL

664064

3.1.1.2

698

-

-

664111

3.1.1.2

698

-

recombinant enzyme

695051

3.1.1.2

759

-

mutant H115W/R192K, pH 8.0, 25°C

729324

3.1.1.2

796

-

pH 8.0, 25°C

729339

3.1.1.2

843.6

-

pH 8.0, temperature not specified in the publication

730898

3.1.1.2

843.6

-

wild-type, pH 8.0, 25°C

729324

3.1.1.2

850

-

in 50 mM Tris-HCl buffer, 10 mM CaCl2, pH 7.4

708095

3.1.1.2

854

-

pH 8.0, wild-type enzyme

665745

3.1.1.2

1200

-

pH 8.0, 30°C

729339

3.1.1.2

1541

-

pH 8.0, 35°C

729339

3.1.1.2

1901

-

pH 8.0, 40°C

729339

3.1.1.2

3373

-

pH 7.4, 37°C, type B paraoxonase

35213

3.1.1.2

4778

-

pH 7.4, 37°C, type A paraoxonase

35213

3.1.1.1

5 entries

3.1.1.2

27 entries

3.1.1.6

3

-

recombinant enzyme, pH 6.4

652394

3.1.8.1

89

-

recombinant PON3

663985

3.1.8.1

552

-

pH 8.0, recombinant genetic variant G1C4

666714

3.1.8.1

562

-

pH 8.0, recombinant genetic variant G2D6

666714

3.1.8.1

789

-

pH 8.0, recombinant genetic variant G3C9

666714

3.1.8.1

833

-

pH 8.0, recombinant genetic variant G1A5

666714

3.1.8.1

965

-

pH 8.0, recombinant genetic variant G2E6

666714

3.1.8.1

1018

-

pH 8.0, recombinant genetic variant G3H8

666714

3.1.8.1

1236

-

pH 8.0, recombinant wild-type PON1

666714

3.1.8.1

8 entries

6.2.1.75

0.48

-

pH and temperature not specified in the publication

764580

K_M Value (73 results)

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Show KM Value (73 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

3.1.1.1

0.05

-

isoenzyme V

171000

3.1.1.1

0.43

-

isoenzyme I

171000

3.1.1.1

0.93

-

pH 7.5, 30°C

652627

3.1.1.1

2.8

-

in 2.5 mM Bicine buffer, pH 8.3, at 30°C

729255

3.1.1.1

4

-

pH 8.0, 22°C

679382

3.1.1.1

35

-

pH 7.5, 30°C

652627

3.1.1.2

0.01

-

pH 7.0, 25°

729864

3.1.1.2

0.014

-

wild type enzyme, in simulated body fluid, at pH 7.34-7.4 and 37°C

692124

3.1.1.2

0.017

-

recombinant wild type enzyme, in 100 mM sodium phosphate buffer (pH 7.0), at 60°C

692889

3.1.1.2

0.069

-

immobilized cross-linked enzyme aggregate, at pH 7.0 and 25°C

750166

3.1.1.2

0.201

-

wild type enzyme, in 20 mM Tris-HCl and 0.9 mM CaCl2, at pH 8 and 25°C

692124

3.1.1.2

0.265

-

pH 7.4, 37°C, type B paraoxonase

35213

3.1.1.2

0.265

-

pH 8.0, 25°C, enzyme from phenotype B blood plasma

35212

3.1.1.2

0.27

-

enzyme variant R192

650953

3.1.1.2

0.4

-

enzyme of breed Holstein, pH 8.0, 25°C

729013

3.1.1.2

0.46

-

wild type enzyme, in simulated body fluid, at pH 7.34-7.4 and 37°C

692124

3.1.1.2

0.5

-

enzyme of breed Montofon, pH 8.0, 25°C

729013

3.1.1.2

0.5

-

in 50 mM Tris-HCl buffer, 10 mM CaCl2, pH 7.4

708095

3.1.1.2

0.51

-

mutant E313A, pH 8.0, 25°C

664184

3.1.1.2

0.53

-

in 50 mM Tris-HCl (pH 8.0), at 37°C

713914

3.1.1.2

0.59

-

mutant N133S, pH 8.0, 25°C

664184

3.1.1.2

0.61

-

pH 8.0, 25°C, wild-type enzyme

664885

3.1.1.2

0.61

-

wild-type, pH 8.0, 25°C

664184

3.1.1.2

0.64

-

mutant G11S, pH 8.0, 25°C

664184

3.1.1.2

0.64

-

wild type enzyme, in 20 mM Tris-HCl and 0.9 mM CaCl2, at pH 8 and 25°C

692124

3.1.1.2

0.67

-

mutant E314A, pH 8.0, 25°C

664184

3.1.1.2

0.68

-

pH 8.0, 10°C

729339

3.1.1.2

0.688

-

pH 7.4, 37°C, type A paraoxonase

35213

3.1.1.2

0.688

-

pH 8.0, 25°C, enzyme from phenotype A blood plasma

35212

3.1.1.2

0.7

-

enzyme variant Q192

650953

3.1.1.2

0.74

-

2 mM substrate, at pH 8.0 and 37°C

707214

3.1.1.2

0.74

-

mutant G11A or mutant G11C, pH 8.0, 25°C

664184

3.1.1.2

0.8

-

enzyme of breed Swiss Black, pH 8.0, 25°C

729013

3.1.1.2

0.8

-

pH 8.3, activity buffer with 0.01 mM apolipoprotein apoA-I rHDL

664064

3.1.1.2

0.81

-

pH 8.0, 25°C, mutant enzyme F222Y

664885

3.1.1.2

0.86

-

wild type enzyme, in 50 mM Tris-HCl with 1 mM CaCl2 (pH 8.0), at 25°C

690419

3.1.1.2

0.89

-

mutant enzyme Q192R, in 50 mM Tris-HCl with 1 mM CaCl2 (pH 8.0), at 25°C

690419

3.1.1.2

0.89

-

mutant F222Y, pH 8.0, 25°C

664184

3.1.1.2

0.92

-

isozyme 192R, in 50 mM Tris-HCl (pH 8.0), 1 mM CaCl2, 25°C

715735

3.1.1.2

0.957

-

recombinant wild type enzyme, in 0.1 M Tris-HCl (pH 8.5), 2 M NaCl, and 2 mM CaCl2

694871

3.1.1.2

0.97

-

pH 8.0, 15°C

729339

3.1.1.2

0.98

-

isozyme 192Q, in 50 mM Tris-HCl (pH 8.0), 1 mM CaCl2, 25°C

715735

3.1.1.2

1

2.1

-

35204

3.1.1.2

1.05

-

pH 8.0, 20°C

729339

3.1.1.2

1.2

-

-

664111

3.1.1.2

1.2

-

recombinant enzyme

695051

3.1.1.2

1.3

-

pH 8.0, wild-type enzyme

665745

3.1.1.2

1.33

-

pH 8.0, 25°C

729339

3.1.1.2

1.6

-

pH 8.3, activity buffer with 0.1% tergitol

664064

3.1.1.2

1.8

-

pH 8.0, 30°C

729339

3.1.1.2

2.07

-

pH 8.0, 35°C

729339

3.1.1.2

2.1

-

pH 8.0, temperature not specified in the publication

730898

3.1.1.2

2.1

-

wild-type, pH 8.0, 25°C

729324

3.1.1.2

2.6

-

pH 8.3, activity buffer

664064

3.1.1.2

3.03

-

pH 8.0, 40°C

729339

3.1.1.2

3.6

-

pH 8.0, mutant enzyme H134Q

665745

3.1.1.2

3.7

-

pH 8.0, wild-type enzyme

652704

3.1.1.2

3.8

-

pH 8.0, recombinant enzyme

652704

3.1.1.2

4.1

-

mutant H115W/R192K, pH 8.0, 25°C

729324

3.1.1.2

7.46

-

pH 8.0, 37°C

663985

3.1.1.2

7.47

-

pH 8.0, 37°C

670788

3.1.1.2

8.1

-

pH 8.0, mutant enzyme H115Q

665745

3.1.1.2

8.18

-

pH 8.3, 25°C

729510

3.1.1.2

9.7

-

pH 8.0, mutant enzyme H115Q/H134Q

665745

3.1.1.2

10.8

-

mutant H115W, pH 8.0, 25°C

729324

3.1.1.2

16

-

EstB, pH 7.5, 30°C

652628

3.1.1.1

6 entries

3.1.1.2

60 entries

3.1.1.25

0.83

-

pH 8.0, 37°C

670788

3.1.1.55

0.0018

-

pH 7.8, 25°C, isozyme I

646021

3.1.1.55

0.0026

-

pH 7.8, 25°C, isozyme II

646021

3.1.1.55

2 entries

3.1.1.6

0.07

-

recombinant enzyme, pH 6.4

652394

3.1.8.1

1.4

-

pH 8.0, wild-type enzyme

652704

3.1.8.1

3.5

-

pH 8.0, recombinant enzyme

652704

3.1.8.1

2 entries

6.2.1.75

0.42

-

pH and temperature not specified in the publication

764580

K_i Value (5 results)

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Show KI Value (5 entries)

EC NUMBER

KI VALUE [MM]

KI VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

3.1.1.2

0.401

-

pH 8.0, 25°C, enzyme from phenotype B blood plasma

35212

3.1.1.2

0.885

-

pH 8.0, 25°C, enzyme from phenotype A blood plasma

35212

3.1.8.1

0.47

-

pH 8.5, 25°C, wild-type enzyme, substrate paraoxon

664885

3.1.8.1

0.91

-

pH 10.5, 25°C, wild-type enzyme, substrate paraoxon

664885

3.1.8.1

1.95

-

pH 10.5, 25°C, mutant enzyme H115W, substrate paraoxon

664885

3.1.1.2

2 entries

3.1.8.1

3 entries

References & Links

Literature References (131)

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Show Reference (131 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

35193

-

Measurement of acetylxylan esterase in Streptomyces

1988

Johnson, K.G.; Fontana, J.D.; MacKenzie, C.R.

Methods Enzymol.

160

551-560

35195

-

Purification and some properties of an esterase from yeast

1986

Toshimitsu, N.; Hamada, H.; Kojima, M.

J. Ferment. Technol.

64

459-462

35199

6870256

Acylhydrolases from parsley (Petroselinum hortense). Relative distribution and properties of four esterases hydrolyzing malonic acid hemiesters of flavonoid glucosides

1983

Matern, U.

Arch. Biochem. Biophys.

224

261-271

35200

-

Esterase activity in the hepatopancreas of Macrobrachium lamerrei (Crustacea: Decapoda)

1980

Murthy, R.C.; Saxena, P.

Experientia

36

323-325

35201

175783

Further evidence for the concept of bovine plasma arylesterase as a lipoprotein

1975

Don, M.M.; Masters, C.J.; Winzor, D.J.

Biochem. J.

151

625-630

35203

4214592

Characterization of the esterases of feline serum

1974

Ecobichon, D.J.

Can. J. Biochem.

52

1073-1078

35204

4798183

Effects of lipid removal on the molecular size and kinetic properties of bovine plasma arylesterase

1973

Kitchen, B.J.; Masters, C.J.; Winzor, D.J.

Biochem. J.

135

93-99

35206

5047702

Membrane marker enzymes. Characterization of an arylesterase of guinea pig cerebral cortex utilizing p-nitrophenyl acetate as substrate

1972

Bosmann, H.B.

Biochim. Biophys. Acta

276

180-191

35207

8597092

Catalytic properties and distribution profiles of paraoxonase and cholinesterase phenotypes in human sera

1995

Reiner, E.; Simeon-Rudolf, V.; Skrinjaric-Spoljar, M.

Toxicol. Lett.

82/83

447-452

35212

1673382

Purification of human serum paraoxonase/arylesterase. Evidence for one esterase catalyzing both activities

1991

Gan, K.N.; Smolen, A.; Eckerson, H.W.; La Du, B.N.

Drug Metab. Dispos.

19

100-106

35213

1673383

Characteristics of the genetically determined allozymic forms of human serum paraoxonase/arylesterase

1991

Smolen, A.; Eckerson, H.W.; Gan, K.N.; Hailat, N.; La Du, B.N.

Drug Metab. Dispos.

19

107-112

35215

1525262

A new automated method for phenotyping arylesterase (EC 3.1.1.2) based upon inhibition of enzymatic hydrolysis of 4-nitrophenyl acetate by phenyl acetate

1992

Haagen, L.; Brock, A.

Eur. J. Clin. Chem. Clin. Biochem.

30

391-395

35217

9732404

Purification of two rat hepatic proteins with A-esterase activity toward chlorpyrifos-oxon and paraoxon

1998

Pond, A.L.; Chambers, H.W.; Coyne, C.P.; Chamers, J.E.

J. Pharmacol. Exp. Ther.

286

1404-1411

35220

9717512

Inhibition of arylesterase by aliphatic alcohols

1998

Debord, J.; Dantoine, T.; Bollinger, J.C.; Abraham, M.H.; Verneuil, B.; Merle, L.

Chem. Biol. Interact.

113

105-115

171000

446478

Characterization of the isoenzymes of pig-liver esterase. 2. Kinetic studies

1979

Junge, W.; Heymann, E.

Eur. J. Biochem.

95

519-525

171001

738990

Purification and enzymatic properties of rat serum carboxylesterase

1978

Hashinotsume, M.; Higashino, K.; Hada, T.; Yamamura, Y.

J. Biochem.

84

1325-1333

171008

4118

Characterization of intracellular esterase A from Bacillus subtilis

1976

Riefler III, J.F.; Higerd, T.B.

Biochim. Biophys. Acta

429

191-197

171010

-

Carboxylesterase from pig and ox liver

1975

Dudman, N.P.B.; Zerner, B.

Methods Enzymol.

35B

190-208

171011

237618

Carboxylesterases (EC 3.1.1). A comparison of some kinetic properties of horse, sheep, chicken, pig, and ox liver carboxylesterases

1975

Stoops, J.K.; Hamilton, S.E.; Zerner, B.

Can. J. Biochem.

53

565-573

171017

3651439

Purification and characterization of a carboxylesterase from the intestine of the nematode Caenorhabditis elegans

1987

McGhee, J.D.

Biochemistry

26

4101-4107

171026

7764506

Cloning of Pseudomonas fluorescens carboxylesterase gene and characterization of its product expressed in Escherichia coli

1994

Kim, Y.S.; Lee, H.B.; Choi, K.D.; Park, S.; Yoo, O.J.

Biosci. Biotechnol. Biochem.

58

111-116

644553

11322873

4- Hydroxyacetophenone monooxygenase from Pseudomonas fluorescens ACB: a novel flavoprotein catalyzing Baeyer-Villiger oxidation of aromatic compounds

2001

Kamerbeek, N.M.; Moonen, M.J.; van der Ven, J.G.; van Berkel, W.J.H.; Fraaije, M.W.; Janssen, D.B.

Eur. J. Biochem.

268

2547-2557

646021

2383281

Aspirin hydrolyzing esterases from rat liver cytosol

1990

Kim, D.H.; Yang, Y.S.; Jakoby, W.B.

Biochem. Pharmacol.

40

481-487

646509

8393742

Studies on human serum paraoxonase/arylesterase

1993

La Du, B.N.; Adkins, S.; Kuo, C.L.; Lipsig, D.

Chem. Biol. Interact.

87

25-34

646521

10421461

Identification of two rat liver proteins with paraoxonase activity: biochemical evidence for the identity of paraoxonase and arylesterase

1999

Rodrigo, L.; Gil, F.; Hernandez, A.F.; Pla, A.

Chem. Biol. Interact.

119-120

263-275

646527

8565784

Comparison of purified human and rabbit serum paraoxonases

1995

Kuo, C.L.; La Du, B.N.

Drug Metab. Dispos.

23

935-944

646528

11259353

Serum paraoxonase (PON1) isozymes: the quantitative analysis of isozymes affecting individual sensitivity to environmental chemicals

2001

La Du, B.N.; Billecke, S.; Hsu, C.; Haley, R.W.; Broomfield, C.A.

Drug Metab. Dispos.

29

566-569

646535

8634243

Three-dimensional structure of the zinc-containing phosphotriesterase with the bound substrate analog diethyl 4-methylbenzylphosphonate

1996

Vanhooke, J.L.; Benning, M.M.; Raushel, F.M.; Holden, H.M.

Biochemistry

35

6020-6025

649387

12514023

Substrate specificity and enantioselectivity of 4-hydroxyacetophenone monooxygenase

2003

Kamerbeek, N.M.; Olsthoorn, A.J.J.; Fraaije, M.W.; Janssen, D.B.

Appl. Environ. Microbiol.

69

419-426

649767

12946270

Identification of paraoxonase 3 in rat liver microsomes: purification and biochemical properties

2003

Rodrigo, L.; Gil, F.; Hernandez, A.F.; Lopez, O.; Pla, A.

Biochem. J.

376

261-268

650864

11412818

Continuous monitoring of arylesterase in human serum

2001

Lorentz, K.; Wirtz, W.; Weiss, T.

Clin. Chim. Acta

308

69-78

650953

11038162

Human serum paraoxonase (PON1) isozymes Q and R hydrolyze lactones and cyclic carbonate esters

2000

Billecke, S.; Draganov, D.; Counsell, R.; Stetson, P.; Watson, C.; Hsu, C.; La Du, B.N.

Drug Metab. Dispos.

28

1335-1342

651605

10792515

Characterization of an arylesterase from Lactobacillus helveticus CNRZ32

2000

Fenster, K.M.; Parkin, K.L.; Steele, J.L.

J. Appl. Microbiol.

88

572-583

651670

11073896

Conversion of 4-hydroxyacetophenone into 4-phenyl acetate by a flavin adenine dinucleotide-containing Baeyer-Villiger-type monooxygenase

2000

Tanner, A.; Hopper, D.J.

J. Bacteriol.

182

6565-6569

652394

12421810

Observation of an arsenic adduct in an acetyl esterase crystal structure

2003

Zhu, X.; Larsen, N.A.; Basran, A.; Bruce, N.C.; Wilson, I.A.

J. Biol. Chem.

278

2008-2014

652627

12741535

Intracellular esterase from Lactobacillus casei LILA: nucleotide sequencing, purification, and characterization

2003

Fenster, K.M.; Parkin, K.L.; Steele, J.L.

J. Dairy Sci.

86

1118-1129

652628

12939078

Nucleotide sequencing, purification, and biochemical properties of an arylesterase from Lactobacillus casei LILA

2003

Fenster, K.M.; Parkin, K.L.; Steele, J.L.

J. Dairy Sci.

86

2547-2557

652704

11369803

Baculovirus-mediated expression and purification of human serum paraoxonase 1A

2001

Brushia, R.J.; Forte, T.M.; Oda, M.N.; La Du, B.N.; Bielicki, J.K.

J. Lipid Res.

42

951-958

653767

12880765

Cloning, heterologous expression, renaturation, and characterization of a cold-adapted esterase with unique primary structure from a psychrotroph Pseudomonas sp. strain B11-1

2003

Suzuki, T.; Nakayama, T.; Choo, D.W.; Hirano, Y.; Kurihara, T.; Nishino, T.; Esaki, N.

Protein Expr. Purif.

30

171-178

663985

16099434

Cloning, high level expression of human paraoxonase-3 in Sf9 cells and pharmacological characterization of its product

2005

Lu, H.; Zhu, J.; Zang, Y.; Ze, Y.; Qin, J.

Biochem. Pharmacol.

70

1019-1025

664064

16128586

High affinity, stability, and lactonase activity of serum paraoxonase PON1 anchored on HDL with ApoA-I

2005

Gaidukov, L.; Tawfik, D.S.

Biochemistry

44

11843-11854

664111

15835926

Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase

2005

Khersonsky, O.; Tawfik, D.S.

Biochemistry

44

6371-6382

664184

15450851

Structure/function analyses of human serum paraoxonase (HuPON1) mutants designed from a DFPase-like homology model

2004

Yeung, D.T.; Josse, D.; Nicholson, J.D.; Khanal, A.; McAndrew, C.W.; Bahnson, B.J.; Lenz, D.E.; Cerasoli, D.M.

Biochim. Biophys. Acta

1702

67-77

664620

15459089

Distribution spectrum of paraoxonase activity in HDL fractions

2004

Bergmeier, C.; Siekmeier, R.; Gross, W.

Clin. Chem.

50

2309-2315

664885

15853807

Analysis of active-site amino-acid residues of human serum paraoxonase using competitive substrates

2005

Yeung, D.T.; Lenz, D.E.; Cerasoli, D.M.

FEBS J.

272

2225-2230

664937

15251439

Senescence marker protein-30 is a unique enzyme that hydrolyzes diisopropyl phosphorofluoridate in the liver

2004

Kondo, Y.; Ishigami, A.; Kubo, S.; Handa, S.; Gomi, K.; Hirokawa, K.; Kajiyama, N.; Chiba, T.; Shimokado, K.; Maruyama, N.

FEBS Lett.

570

57-62

665028

15621715

Effect of 3,4-dihydroxyphenylalanine on Cu2+-induced inactivation of HDL-associated paraoxonase1 and oxidation of HDL; inactivation of paraoxonase1 activity independent of HDL lipid oxidation

2004

Nguyen, S.D.; Sok, D.E.

Free Radic. Res.

38

969-976

665745

16407305

The histidine 115-histidine 134 dyad mediates the lactonase activity of mammalian serum paraoxonases

2006

Khersonsky, O.; Tawfik, D.S.

J. Biol. Chem.

281

7649-7656

665960

15772423

Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities

2005

Draganov, D.I.; Teiber, J.F.; Speelman, A.; Osawa, Y.; Sunahara, R.; La Du, B.N.

J. Lipid Res.

46

1239-1247

666183

15805725

Bovine paraoxonase 1 activities in serum and distribution in lipoproteins

2005

Miyamoto, T.; Takahashi, Y.; Oohashi, T.; Sato, K.; Oikawa, S.

J. Vet. Med. Sci.

67

243-248

666714

14695884

Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization

2004

Aharoni, A.; Gaidukov, L.; Yagur, S.; Toker, L.; Silman, I.; Tawfik, D.S.

Proc. Natl. Acad. Sci. USA

101

482-487

670788

16139510

Cloning, purification, and refolding of human paraoxonase-3 expressed in Escherichia coli and its characterization

2006

Lu, H.; Zhu, J.; Zang, Y.; Ze, Y.; Qin, J.

Protein Expr. Purif.

46

92-99

677297

17106515

Activity of paraoxonase 1 (PON1) and its relationship to markers of lipoprotein oxidation in healthy Slovaks

2006

Sumegova, K.; Blazicek, P.; Waczulikova, I.; Zitnanova, I.; Durackova, Z.

Acta Biochim. Pol.

53

783-787

677411

16613735

Paraoxonase/arylesterase in serum of patients with type II diabetes mellitus

2006

Juretic, D.; Motejlkova, A.; Kunovi?, B.; Reki?, B.; Flegar-Mestri?, Z.; Vuji?, L.; Mesi?, R.; Lukac-Bajalo, J.; Simeon-Rudolf, V.

Acta Pharm.

56

59-68

678376

16674912

Preferable stimulation of PON1 arylesterase activity by phosphatidylcholines with unsaturated acyl chains or oxidized acyl chains at sn-2 position

2006

Nguyen, S.D.; Sok, D.E.

Biochim. Biophys. Acta

1758

499-508

678464

17556053

Stability of highly purified human paraoxonase (PON1): Association with human phosphate binding protein (HPBP) is essential for preserving its active conformation(s)

2007

Rochu, D.; Renault, F.; Clery-Barraud, C.; Chabriere, E.; Masson, P.

Biochim. Biophys. Acta

1774

874-883

679262

17920578

Paraoxonase/arylesterase ratio, PON1 192Q/R polymorphism and PON1 status are associated with increased risk of ischemic stroke

2008

Can Demirdoegen, B.; Tuerkanoglu, A.; Bek, S.; Sanisoglu, Y.; Demirkaya, S.; Vural, O.; Arinc, E.; Adali, O.

Clin. Biochem.

41

1-9

679293

17593248

The effect of diet on paraoxonase 1/arylesterase activities in patients with disorders of galactose metabolism

2007

Schulpis, K.H.; Karikas, G.A.; Bartzeliotou, A.; Papakonstantinou, E.D.; Kalogerakou, M.; Tsakiris, S.

Clin. Endocrinol. (Oxf.)

67

687-692

679306

16642406

Paraoxonase and arylesterase levels in rheumatoid arthritis

2007

Isik, A.; Koca, S.S.; Ustundag, B.; Celik, H.; Yildirim, A.

Clin. Rheumatol.

26

342-348

679382

17294326

EstA from Arthrobacter nitroguajacolicus Rue61a, a thermo- and solvent-tolerant carboxylesterase related to class C beta-lactamases

2007

Schuette, M.; Fetzner, S.

Curr. Microbiol.

54

230-236

679634

17203019

Serum paraoxonase/arylesterase activities in phenylketonuric patients on diet

2007

Schulpis, K.H.; Bartzeliotou, A.; Tsakiris, S.; Gounaris, A.; Papassotiriou, I.

Eur. J. Clin. Nutr.

61

803-808

681055

16595195

Tandem purification of two HDL-associated partner proteins in human plasma, paraoxonase (PON1) and phosphate binding protein (HPBP) using hydroxyapatite chromatography

2006

Renault, F.; Chabriere, E.; Andrieu, J.; Dublet, B.; Masson, P.; Rochu, D.

J. Chromatogr. B

836

15-21

681730

16808151

Differential effect of lysophospholipids on activities of human plasma paraoxonase1, either soluble or lipid-bound

2006

Park, C.H.; Nguyen, S.D.; Kim, M.R.; Jeong, T.S.; Sok, D.E.

Lipids

41

371-380

690390

18458312

Decreased serum paraoxonase-1 activity during intestinal nematode (Nippostrongylus brasiliensis) infection in rats

2008

Farid, A.S.; Nakahara, K.; Murakami, N.; Hayashi, T.; Horii, Y.

Am. J. Trop. Med. Hyg.

78

770-776

690419

18952040

Paraoxonase activity against nerve gases measured by capillary electrophoresis and characterization of human serum paraoxonase (PON1) polymorphism in the coding region (Q192R)

2009

Kanamori-Kataoka, M.; Seto, Y.

Anal. Biochem.

385

94-100

690676

18585720

Di-oleoyl phosphatidylcholine (PC-18:1) stimulates paraoxonase 1 (PON1) enzymatic and biological activities: in vitro and in vivo studies

2009

Efrat, M.; Rosenblat, M.; Mahmood, S.; Vaya, J.; Aviram, M.

Atherosclerosis

202

461-469

691230

18572410

Characterization of the PON1 active site using modeling simulation, in relation to PON1 lactonase activity

2008

Tavori, H.; Khatib, S.; Aviram, M.; Vaya, J.

Bioorg. Med. Chem.

16

7504-7509

691536

18590589

Growth hormone improves lipoprotein concentration and arylesterase activity in mice with an atherogenic lipid profile induced by lactalbumin

2009

Lopez-Oliva, E.; Nus, M.; Agis-Torres, A.; Villaro, W.; Sanchez-Montero, J.M.; Munoz-Martinez, E.; Sanchez-Muniz, F.J.

Br. J. Nutr.

101

518-526

691851

18423402

Paraoxonase 1 (PON1) status in gastroesophageal malignancies and associated paraneoplastic syndromes - connection with inflammation

2008

Krzystek-Korpacka, M.; Boehm, D.; Matusiewicz, M.; Diakowska, D.; Grabowski, K.; Gamian, A.

Clin. Biochem.

41

804-811

691855

18976644

Arylesterase and paraoxonase activity of paraoxonase (PON1) affected by ischemia in the plasma of patients with arterial occlusion of the lower limbs

2009

Kasprzak, M.; Iskra, M.; Majewski, W.; Wielkoszynski, T.

Clin. Biochem.

42

50-56

691863

18601602

High-density lipoprotein cholesterol and paraoxonase 1 (PON1) genetics and serum PON1 activity in prepubertal children in Spain

2008

Garces, C.; Lopez-Simon, L.; Rubio, R.; Benavente, M.; Cano, B.; Ortega, H.; de Oya, M.

Clin. Chem. Lab. Med.

46

809-813

691873

18505467

High plasma C-reactive protein (CRP) is related to low paraoxonase-I (PON-I) activity independently of high leptin and low adiponectin in type 2 diabetes mellitus

2009

Dullaart, R.P.; de Vries, R.; Sluiter, W.J.; Voorbij, H.A.

Clin. Endocrinol. (Oxf.)

70

221-226

692124

-

Determination of rat and mice arylesterase activity using serum mimetics

2008

Nus, M.; Sanchez-Muniz, F.J.; Gago, J.V.; Lopez-Oliva, E.; Sanchez-Montero, J.M.

Enzyme Microb. Technol.

43

252-256

692245

18032000

Increased glutathione levels and activity of PON1 (phenyl acetate esterase) in the liver of rats after a single dose of cyclophosphamide: a defense mechanism?

2008

Abraham, P.; Sugumar, E.

Exp. Toxicol. Pathol.

59

301-306

692541

19101714

Serum paraoxonase and arylesterase activities in patients with epithelial ovarian cancer

2009

Camuzcuoglu, H.; Arioz, D.T.; Toy, H.; Kurt, S.; Celik, H.; Erel, O.

Gynecol. Oncol.

112

481-485

692695

19402863

Baseline and salt-stimulated paraoxonase and arylesterase activities in patients with chronic liver disease: Relation with disease severity

2009

Keskin, M.; Dolar, E.; Dirican, M.; Kiyici, M.; Yilmaz, Y.; Gurel, S.; Nak, S.G.; Erdinc, S.; Gulten, M.

Intern. Med. J.

39

243-248

692732

18759451

Consumption of wonderful variety pomegranate juice and extract by diabetic patients increases paraoxonase 1 association with high-density lipoprotein and stimulates its catalytic activities

2008

Rock, W.; Rosenblat, M.; Miller-Lotan, R.; Levy, A.P.; Elias, M.; Aviram, M.

J. Agric. Food Chem.

56

8704-8713

692889

18931117

A novel thermostable arylesterase from the archaeon Sulfolobus solfataricus P1: purification, characterization, and expression

2008

Park, Y.J.; Yoon, S.J.; Lee, H.B.

J. Bacteriol.

190

8086-8095

693321

18624774

Paraoxonase 1 activities and polymorphisms in autism spectrum disorders

2010

Pasca, S.P.; Dronca, E.; Nemes, B.; Kaucsar, T.; Endreffy, E.; Iftene, F.; Benga, I.; Cornean, R.; Dronca, M.

J. Cell. Mol. Med.

14

600-607

693354

18704198

Drosophila are protected from Pseudomonas aeruginosa lethality by transgenic expression of paraoxonase-1

2008

Stoltz, D.A.; Ozer, E.A.; Taft, P.J.; Barry, M.; Liu, L.; Kiss, P.J.; Moninger, T.O.; Parsek, M.R.; Zabner, J.

J. Clin. Invest.

118

3123-3131

693357

19288455

Serum lipid profile, oxidative status, and paraoxonase 1 activity in hyperemesis gravidarum

2009

Aksoy, H.; Aksoy, A.N.; Ozkan, A.; Polat, H.

J. Clin. Lab. Anal.

23

105-109

693586

18337701

Cloning and characterization of thermostable esterase from Archaeoglobus fulgidus

2008

Kim, S.B.; Lee, W.; Ryu, Y.W.

J. Microbiol.

46

100-107

694369

18347314

Paraoxonase 1 (PON1) organophosphate hydrolysis is not reduced in ALS

2008

Wills, A.M.; Landers, J.E.; Zhang, H.; Richter, R.J.; Caraganis, A.J.; Cudkowicz, M.E.; Furlong, C.E.; Brown, R.H.

Neurology

70

929-934

694871

18711144

Engineered recombinant human paraoxonase 1 (rHuPON1) purified from Escherichia coli protects against organophosphate poisoning

2008

Stevens, R.C.; Suzuki, S.M.; Cole, T.B.; Park, S.S.; Richter, R.J.; Furlong, C.E.

Proc. Natl. Acad. Sci. USA

105

12780-12784

695051

18951406

In silico analyses of substrate interactions with human serum paraoxonase 1

2009

Hu, X.; Jiang, X.; Lenz, D.E.; Cerasoli, D.M.; Wallqvist, A.

Proteins

75

486-498

695124

19016076

Early effects of sodium valproate monotherapy on serum paraoxonase/arylesterase activities

2009

Karikas, G.A.; Schulpis, K.H.; Bartzeliotou, A.; Regoutas, S.; Thanopoulou, C.; Papaevangelou, V.; Giannoulia-Karantana, A.; Papassotiriou, I.; Fytou-Pallikari, A.

Scand. J. Clin. Lab. Invest.

69

31-35

695193

19071155

Paraoxonase 1 (PON1) status and substrate hydrolysis

2009

Richter, R.J.; Jarvik, G.P.; Furlong, C.E.

Toxicol. Appl. Pharmacol.

235

1-9

696095

18513186

Localization and characterization of the novel protein encoded by C20orf3

2008

Ilhan, A.; Gartner, W.; Nabokikh, A.; Daneva, T.; Majdic, O.; Cohen, G.; Boehmig, G.A.; Base, W.; Hoerl, W.H.; Wagner, L.

Biochem. J.

414

485-495

702421

19103263

Oxidative inactivation of lactonase activity of purified human paraoxonase 1 (PON1)

2009

Nguyen, S.D.; Hung, N.D.; Cheon-Ho, P.; Ree, K.M.; Dai-Eun, S.

Biochim. Biophys. Acta

1790

155-160

703470

19750105

Serum cholinesterase inhibition in relation to paraoxonase-1 (PON1) status among organophosphate-Exposed agricultural pesticide handlers

2009

Hofmann, J.; Keifer, M.; Furlong, C.; De Roos, A.; Farin, F.; Fenske, R.; van Belle, G.; Checkoway, H.

Environ. Health Perspect.

117

1402-1408

707155

18635596

Anti-inflammatory therapy with tumour necrosis factor alpha inhibitors improves high-density lipoprotein cholesterol antioxidative capacity in rheumatoid arthritis patients

2009

Popa, C.; van Tits, L.J.; Barrera, P.; Lemmers, H.L.; van den Hoogen, F.H.; van Riel, P.L.; Radstake, T.R.; Netea, M.G.; Roest, M.; Stalenhoef, A.F.

Ann. Rheum. Dis.

68

868-872

707214

19902382

Synthesis of cholesterol-conjugated magnetic nanoparticles for purification of human paraoxonase 1

2010

Samra, Z.Q.; Shabir, S.; Rehmat, Z.; Zaman, M.; Nazir, A.; Dar, N.; Athar, M.A.

Appl. Biochem. Biotechnol.

162

671-686

708095

20176005

Purification and characterization of functional human paraoxonase-1 expressed in Trichoplusia ni larvae

2010

Otto, T.C.; Kasten, S.A.; Kovaleva, E.; Liu, Z.; Buchman, G.; Tolosa, M.; Davis, D.; Smith, J.R.; Balcerzak, R.; Lenz, D.E.; Cerasoli, D.M.

Chem. Biol. Interact.

187

388-392

709261

19945920

Integrative analytical approach by capillary electrophoresis and kinetics under high pressure optimized for deciphering intrinsic and extrinsic cofactors that modulate activity and stability of human paraoxonase (PON1)

2010

Renault, F.; Carus, T.; Clery-Barraud, C.; Elias, M.; Chabriere, E.; Masson, P.; Rochu, D.

J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.

878

1346-1355

709755

19698032

Decreased paraoxonase and arylesterase activities in the pathogenesis of future atherosclerotic heart disease in women with gestational diabetes mellitus

2009

Camuzcuoglu, H.; Toy, H.; Cakir, H.; Celik, H.; Erel, O.

J. Womens Health (Larchmt)

18

1435-1439

713914

21533577

Molecular cloning and characterization of a novel SGNH arylesterase from the goat rumen contents

2011

Wang, G.; Meng, K.; Luo, H.; Wang, Y.; Huang, H.; Shi, P.; Pan, X.; Yang, P.; Yao, B.

Appl. Microbiol. Biotechnol.

91

1561-1570

714002

-

L-arginine ameliorates arylesterase/paraoxonase activity of paraoxonase-1 in hypercholesterolemic rats

2011

Harisa, G.

Asian J. Biochem.

6

263-272

714112

21219877

Protective efficacy of catalytic bioscavenger, paraoxonase 1 against sarin and soman exposure in guinea pigs

2011

Valiyaveettil, M.; Alamneh, Y.; Rezk, P.; Biggemann, L.; Perkins, M.W.; Sciuto, A.M.; Doctor, B.P.; Nambiar, M.P.

Biochem. Pharmacol.

81

800-809

714637

21736796

Effects of Nori- and Wakame-enriched meats with or without supplementary cholesterol on arylesterase activity, lipaemia and lipoproteinaemia in growing Wistar rats

2011

Olivero-David, R.; Schultz-Moreira, A.; Vazquez-Velasco, M.; Gonzalez-Torres, L.; Bastida, S.; Benedi, J.; Isabel Sanchez-Reus, M.; Jose Gonzalez-Munoz, M.; Sanchez-Muniz, F.J.

Br. J. Nutr.

106

1476-1486

714759

21167145

Serum paraoxonase and arylesterase activities in patients with lacunar infarction: a case control study

2011

Moghtaderi, A.; Hashemi, M.; Dabiri, S.; Moazeni-Roodi, A.; Hosseini, M.

Clin. Biochem.

44

288-292

714817

20380152

Activatory effect of substrates on the cholinesterase catalysis

2010

Rozengart, E.; Basova, N.

Dokl. Biochem. Biophys.

430

7-10

714893

21059866

Serum paraoxonase and arylesterase activities in metabolic syndrome in Zahedan, southeast Iran

2011

Hashemi, M.; Kordi-Tamandani, D.M.; Sharifi, N.; Moazeni-Roodi, A.; Kaykhaei, M.A.; Narouie, B.; Torkmanzehi, A.

Eur. J. Endocrinol.

164

219-222

714895

-

Serum paraoxonase and arylesterase activities in esophageal cancer: A controlled study

2010

Cayir, K.; Bilici, M.; Tekin, S.; Kara, F.; Turkyilmaz, A.; Yildirim, A.

Eur. J. Gen. Med.

7

398-403

715735

21123122

Differential hydrolysis of homocysteine thiolactone by purified human serum (192)Q and (192)R PON1 isoenzymes

2011

Bayrak, A.; Bayrak, T.; Demirpence, E.; Kilinc, K.

J. Chromatogr. B

879

49-55

715738

21919063

Serum paraoxonase and arylesterase activities in various forms of hepatitis B virus infection

2011

Duygu, F.; Tekin Koruk, S.; Aksoy, N.

J. Clin. Lab. Anal.

25

311-316

721900

16086253

The putative lipase, AF1763, from Archaeoglobus fulgidus is a carboxylesterase with a very high pH optimum

2005

Rusnak, M.; Nieveler, J.M Schmid, R. D.; Petri, R.

Biotechnol. Lett.

27

743-748

729013

24907040

Purification and characterization of paraoxonase 1 (PON1) from Swiss Black, Holstein, and Montofon bovines

2014

Erzengin, M.; Demir, D.; Arslan, M.; Sinan, S.

Appl. Biochem. Biotechnol.

173

1597-1606

729036

23793626

Characterization of a feruloyl esterase from Lactobacillus plantarum

2013

Esteban-Torres, M.; Reveron, I.; Mancheno, J.M.; de Las Rivas, B.; Munoz, R.

Appl. Environ. Microbiol.

79

5130-5136

729255

24832101

Structural characterization and function determination of a nonspecific carboxylate esterase from the amidohydrolase superfamily with a promiscuous ability to hydrolyze methylphosphonate esters

2014

Xiang, D.F.; Kumaran, D.; Swaminathan, S.; Raushel, F.M.

Biochemistry

53

3476-3485

729324

25107406

Interplay between amino acid residues at positions 192 and 115 in modulating hydrolytic activities of human paraoxonase 1

2014

Bajaj, P.; Aggarwal, G.; Tripathy, R.K.; Pande, A.H.

Biochimie

105

202-210

729339

24096087

Temperature dependence of binding and catalysis for human serum arylesterase/paraoxonase

2014

Debord, J.; Bollinger, J.C.; Harel, M.; Dantoine, T.

Biochimie

97

72-77

729510

24894602

SacPox from the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius is a proficient lactonase

2014

Bzdrenga, J.; Hiblot, J.; Gotthard, G.; Champion, C.; Elias, M.; Chabriere, E.

BMC Res. Notes

7

333

729864

23003572

Molecular characterization of a novel arylesterase from the wine-associated acetic acid bacterium Gluconobacter oxidans 621H

2012

Navarro-Gonzalez, I.; Sanchez-Ferrer, A.; Garcia-Carmona, F.

J. Agric. Food Chem.

60

10789-10795

730898

24123308

Characterization of human paraoxonase 1 variants suggest that His residues at 115 and 134 positions are not always needed for the lactonase/arylesterase activities of the enzyme

2013

Bajaj, P.; Tripathy, R.K.; Aggarwal, G.; Pande, A.H.

Protein Sci.

22

1799-1807

749610

25809994

New chemiluminescent substrates of paraoxonase 1 with improved specificity synthesis and properties

2015

Abulimite, Z.; Mu, X.; Xiao, S.; Liu, M.; Li, Q.; Chen, G.

Appl. Biochem. Biotechnol.

176

301-316

749628

28161867

Towards understanding the catalytic mechanism of human paraoxonase 1 experimental and in silico mutagenesis studies

2017

Tripathy, R.K.; Aggarwal, G.; Bajaj, P.; Kathuria, D.; Bharatam, P.V.; Pande, A.H.

Appl. Biochem. Biotechnol.

182

1642-1662

749762

29199478

Effect of certain non-steroidal anti-inflammatory drugs on the paraoxonase 2 (PON2) in human monocytic cell line U937

2018

Solmaz Avcikurt, A.; Korkut, O.

Arch. Physiol. Biochem.

124

378-382

749840

28389737

Paraoxonase and arylesterase levels in Behcets disease and their relations with the disease activity

2017

Kul, A.; Uzkeser, H.; Ozturk, N.

Biochem. Genet.

55

335-344

750166

26443058

Characterization of cross-linked immobilized arylesterase from Gluconobacter oxydans 621H with activity toward cephalosporin C and 7-aminocephalosporanic acid

2016

Inmaculada, N.; Francisco, G.

Biotechnol. Prog.

32

36-42

750292

26286433

Rational design of paraoxonase 1 (PON1) for the efficient hydrolysis of organophosphates

2015

Le, Q.A.; Chang, R.; Kim, Y.H.

Chem. Commun. (Camb.)

51

14536-14539

750340

27129797

Paraoxonase-1 arylesterase activity is an independent predictor of myeloperoxidase levels in overweight patients with or without cardiovascular complications

2016

Zsiros, N.; Koncsos, P.; Lorincz, H.; Seres, I.; Katko, M.; Szentpeteri, A.; Varga, V.E.; Fueloep, P.; Paragh, G.; Harangi, M.

Clin. Biochem.

49

862-867

750345

28579140

Alteration of paraoxonase, arylesterase and lactonase activities in people around fluoride endemic area of Tamil Nadu, India

2017

Arulkumar, M.; Vijayan, R.; Penislusshiyan, S.; Sathishkumar, P.; Angayarkanni, J.; Palvannan, T.

Clin. Chim. Acta

471

206-215

750428

29306821

The effect of divalent metal chelators and cadmium on serum phosphotriesterase, lactonase and arylesterase activities of paraoxonase 1

2018

Bizon, A.; Milnerowicz, H.

Environ. Toxicol. Pharmacol.

58

77-83

750482

26044217

Serum paraoxonase and arylesterase values as antioxidants in healthy premature infants at fasting and posprandial times

2015

Kahveci, H.; Laloglu, F.; Kilic, O.; Ciftel, M.; Yildirim, A.; Orbak, Z.; Ertekin, V.; Laloglu, E.

Eur. Rev. Med. Pharmacol. Sci.

19

1761-1765

750483

26698256

The activities of serum paraoxonase and arylesterase and lipid profile in acute myeloid leukemia preliminary results

2015

Cebi, A.; Akgun, E.; Esen, R.; Demir, H.; Cifci, A.

Eur. Rev. Med. Pharmacol. Sci.

19

4590-4594

750484

27022137

The common variant Q192R at the paraoxonase 1 (PON1) gene and its activity are responsible for a portion of the altered antioxidant status in type 2 diabetes

2016

Zargari, M.; Sharafeddin, F.; Mahrooz, A.; Alizadeh, A.; Masoumi, P.

Exp. Biol. Med.

241

1489-1496

750511

29782204

Paraoxonase 1 Q192R genotype and activity affect homocysteine thiolactone levels in humans

2018

Perla-Kajan, J.; Borowczyk, K.; Glowacki, R.; Nygard, O.; Jakubowski, H.

FASEB J.

32

6019

750758

27312742

Decreased arylesterase activity of paraoxonase-1 (PON-1) might be a common denominator of neuroinflammatory and neurodegenerative diseases

2016

Castellazzi, M.; Trentini, A.; Romani, A.; Valacchi, G.; Bellini, T.; Bonaccorsi, G.; Fainardi, E.; Cavicchio, C.; Passaro, A.; Zuliani, G.; Cervellati, C.

Int. J. Biochem. Cell Biol.

81

356-363

752150

26795296

Paraoxonase and arylesterase levels in autoimmune thyroid diseases

2016

Korkmaz, H.; Tabur, S.; Ozkaya, M.; Oguz, E.; Elboga, U.; Aksoy, N.; Akarsu, E.

Redox Rep.

21

227-231

752173

25723374

Paraoxonase and arylesterase activities in patients with papillary thyroid cancer

2015

Korkmaz, H.; Tabur, S.; Oezkaya, M.; Aksoy, N.; Yildiz, H.; Akarsu, E.

Scand. J. Clin. Lab. Invest.

75

259-264

764580

27102732

An indoleacetate-CoA ligase and a phenylsuccinyl-CoA transferase involved in anaerobic metabolism of auxin

2016

Schuehle, K.; Nies, J.; Heider, J.

Environ. Microbiol.

18

3120-3132

Links to other databases for phenyl acetate

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