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Ligand dimethyl sulfone Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C2 H6 O2 S
dimethyl sulfone
HHVIBTZHLRERCL-UHFFFAOYSA-N
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
dimethyl sulfone + FMNH2 + O2 = methanesulfinate + formaldehyde + FMN + H2O
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
dimethyl sulfoxide + NADH + H+ + O2 = dimethyl sulfone + NAD+ + H2O
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Substrate in Enzyme-catalyzed Reactions (3 results)
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dimethylsulfone + NADH + H+ + O2 = methanesulfinate + NAD+ + H2O
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dimethyl sulfone + FMNH2 + O2 = methanesulfinate + formaldehyde + FMN + H2O
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dimethyl sulfone + NADH + H+ = dimethyl sulfoxide + H2O + NAD+
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Product in Enzyme-catalyzed Reactions (1 result)
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dimethyl sulfoxide + NADH + H+ + O2 = dimethyl sulfone + NAD+ + H2O
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Activator in Enzyme-catalyzed Reactions (1 result)
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in Hyphomicrobium strain S1, the highest activity of dimethylsulfone reductase is found after growth with dimethylsulfone
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Enzyme Kinetic Parameters
References & Links Literature References (5)
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Dimethylsulfone as a growth substrate for novel methylotrophic species of Hyphomicrobium and Arthrobacter
2000
Borodina, E.; Kelly, D.; Rainey, F.; Ward-Rainey, N.; Wood, A.
Arch. Microbiol.
173
425-437
Enzymes of dimethylsulfone metabolism and the phylogenetic characterization of the facultative methylotrophs Arthrobacter sulfonivorans sp. nov., Arthrobacter methylotrophus sp. nov., and Hyphomicrobium sulfonivorans sp. nov
2002
Borodina, E.; Kelly, D.P.; Schumann, P.; Rainey, F.A.; Ward-Rainey, N.L.; Wood, A.P.
Arch. Microbiol.
177
173-183
The reduced flavin-dependent monooxygenase SfnG converts dimethylsulfone to methanesulfinate
2016
Wicht, D.K.
Arch. Biochem. Biophys.
604
159-166
The sigma54-dependent transcriptional activator SfnR regulates the expression of the Pseudomonas putida sfnFG operon responsible for dimethyl sulphone utilization
2005
Endoh, T.; Habe, H.; Nojiri, H.; Yamane, H.; Omori, T.
Mol. Microbiol.
55
897-911
The reduced flavin-dependent monooxygenase SfnG converts dimethylsulfone to methanesulfinate
2016
Wicht, D.K.
Arch. Biochem. Biophys.
604
159-166
Links to other databases for dimethyl sulfone
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