Ligand alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA
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Basic Ligand Information
Molecular Structure

C84H154N2O37P2
alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA
XAOLJGCZESYRFT-VHSKNIDJSA-N
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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a palmitoleoyl-[acyl-carrier protein] + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA = alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(palmitoleoyl)-lipid IVA + a [acyl-carrier protein]
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Substrate in Enzyme-catalyzed Reactions (3 results)
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a dodecanoyl-[acyl-carrier protein] + Kdo2-lipid IVA = dodecanoyl-Kdo2-lipid IVA + an [acyl-carrier protein]
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a tetradecanoyl-[acyl-carrier protein] + Kdo2-lipid IVA = tetradecanoyl-Kdo2-lipid IVA + an [acyl-carrier protein]
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a palmitoleoyl-[acyl-carrier protein] + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA = alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(palmitoleoyl)-lipid IVA + a [acyl-carrier protein]
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Product in Enzyme-catalyzed Reactions (1 result)
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alpha-Kdo-(2->6)-lipid IVA + CMP-alpha-Kdo = alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP
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Enzyme Kinetic Parameters
References & Links
Literature References (4)
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Role of lipid A acylation in Yersinia enterocolitica virulence
2010
Pérez-Gutiérrez, C.; Llobet, E.; Llompart, C.M.; Reinés, M.; Bengoechea, J.A.
Infect. Immun.
78
2768-2781
Identification of two genes encoding for the late acyltransferases of lipid A in Klebsiella pneumoniae
2016
Li, Y.; Yun, J.; Liu, L.; Li, Y.; Wang, X.
Curr. Microbiol.
73
732-738
Identification and characterization of two Klebsiella pneumoniae lpxL lipid A late acyltransferases and their role in virulence
2017
Mills, G.; Dumigan, A.; Kidd, T.; Hobley, L.; Bengoechea, J.
Infect. Immun.
85
e00068-17
Identification of two secondary acyltransferases of lipid A in Pseudomonas putida KT2442
2017
Zhu, L.; Li, Y.; Wang, J.; Wang, X.
J. Appl. Microbiol.
123
478-490
Links to other databases for alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA