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Ligand Met-Gly-Gly

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (4 results)

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Show Substrate (4 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

3.4.11.13

Met-Gly-Gly + H2O = Met + Gly-Gly

81195, 81196, 81197

-

3.4.11.15

Met-Gly-Gly + H2O = Met + Gly-Gly

647039

-

3.4.11.18

Met-Gly-Gly + H2O = Met + Gly-Gly

708243, 707293

-

3.4.11.4

Met-Gly-Gly + H2O = Met + Gly-Gly

35928, 649359

-

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (3 results)

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Show Turnover Number (3 entries)

EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

3.4.11.18

15.25

-

recombinant isozyme c2MetAP-Ia, pH 7.2, 37°C

707293

3.4.11.18

19.87

-

recombinant isozyme c1MetAP-Ia, pH 7.2, 37°C

707293

3.4.11.18

21.87

-

recombinant isozyme c3MetAP-Ib, pH 7.2, 37°C

707293

3.4.11.18

3 entries

K_M Value (5 results)

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Show KM Value (5 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

3.4.11.18

1.9

-

recombinant isozyme c3MetAP-Ib, pH 7.2, 37°C

707293

3.4.11.18

2.3

-

recombinant isozyme c1MetAP-Ia, pH 7.2, 37°C

707293

3.4.11.18

5.8

-

recombinant isozyme c2MetAP-Ia, pH 7.2, 37°C

707293

3.4.11.4

2.6

-

-

649359

3.4.11.4

5.3

-

-

35928

3.4.11.18

3 entries

3.4.11.4

2 entries

References & Links

Literature References (8)

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Show Reference (8 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

35928

356879

Tripeptide-specific aminopeptidase from Escherichia coli AJ005

1978

Hermsdorf, C.L.

Biochemistry

17

3370-3376

81195

4318

An extracellular aminopeptidase from Clostridium histolyticum

1976

Kessler, E.; Yaron, A.

Eur. J. Biochem.

63

271-287

81196

13266

Extracellular aminopeptidase from Clostridium histolyticum

1976

Kessler, E.; Yaron, A.

Methods Enzymol.

45

544-552

81197

4631895

A novel aminopeptidase from Clostridium histolyticum

1973

Kessler, E.; Yaron, A.

Biochem. Biophys. Res. Commun.

50

405-412

647039

8175799

Aminopeptidase Y, a new aminopeptidase from Saccharomyces cerevisiae. Purification, properties, localization, and processing by protease B

1994

Yasuhara, T.; Nakai, T.; Ohashi, A.

J. Biol. Chem.

269

13644-13650

649359

10653753

Purification and molecular characterization of a tripeptidase (PepT) from Lactobacillus helveticus

2000

Savijoki, K.; Palva, A.

Appl. Environ. Microbiol.

66

794-800

707293

12861438

Molecular cloning, expression and characterization of three distinctive genes encoding methionine aminopeptidases in cyanobacterium Synechocystis sp. strain PCC6803

2003

Atanassova, A.; Sugita, M.; Sugiura, M.; Pajpanova, T.; Ivanov, I.

Arch. Microbiol.

180

185-193

708243

19688379

Expression and characterization of two functional methionine aminopeptidases from Mycobacterium tuberculosis H37Rv

2009

Zhang, X.; Chen, S.; Hu, Z.; Zhang, L.; Wang, H.

Curr. Microbiol.

59

520-525

Links to other databases for Met-Gly-Gly

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Show Links (1 entry)

ChEBI

PubChem

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