Ligand S-sulfanylglutathione

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Basic Ligand Information

Molecular Structure
Picture of S-sulfanylglutathione (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H17N3O6S2
S-sulfanylglutathione
QBOLVLBSUGJHGB-WDSKDSINSA-N
Synonyms:
glutathione persulfide, GSS-

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
S-sulfanylglutathione + O2 = sulfite + glutathione + H+
-

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE
-
show the reaction diagram
hydrogen sulfide + glutathione + a quinone = S-sulfanylglutathione + a quinol
-

Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE

Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
-
show the reaction diagram
glutathione + sulfite + 2 H+ = S-sulfanylglutathione + O2 + H2O
-
-
show the reaction diagram
sulfide + reduced glutathione + coenzyme Q1 = glutathione persulfide + reduced coenzyme Q1
-
-
show the reaction diagram
S-sulfoglutathione + 6 reduced ferredoxin + 6 H+ = glutathione persulfide + 6 oxidized ferredoxin + 3 H2O
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (3 results)

COMMENTARY
EC NUMBER
LITERATURE
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
recombinant mutant C314S, pH 7.4, 22°C
5
-
recombinant wild-type enzyme CstB, pH 6.0, 25°C, coupled persulfide dioxygenase-persulfide transferase activity
6.5
-
recombinant wild-type enzyme, pH 7.4, 22°C
143
-

KM Value (3 results)

COMMENTARY
EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
LITERATURE
recombinant mutant C314S, pH 7.4, 22°C
0.037
-
recombinant wild-type enzyme CstB, pH 6.0, 25°C, coupled persulfide dioxygenase-persulfide transferase activity
0.0078
-
recombinant wild-type enzyme, pH 7.4, 22°C
0.07
-

References & Links

Links to other databases for S-sulfanylglutathione

ChEBI
PubChem
-
PubChem