Ligand N-acetyl-L-leucine

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Basic Ligand Information

Molecular Structure
Picture of N-acetyl-L-leucine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H15NO3
N-acetyl-L-leucine
WXNXCEHXYPACJF-ZETCQYMHSA-N
Synonyms:
Ac-Leu, acetyl-L-leu, acetyl-L-leucine, acetyl-Leu, N-acetyl-L-Leu, N-acetyl-Leu, N-acetylleucine, N-alpha-acetyl-L-leucine, Nalpha-acetyl-L-Leu, Nalpha-acetyl-L-leucine, Nalpha-acetyl-Leu

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetyl-CoA + L-leucine = CoA + N-acetyl-L-leucine
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N-acetyl-L-Leu + H2O = L-Leu + acetate
show the reaction diagram
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Nalpha-acetyl-L-leucine + H2O = L-leucine + acetate
show the reaction diagram
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Nalpha-acetyl-L-Leu + H2O = methanol + CO2 + L-Leu
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (21 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetyl-CoA + L-leucine = CoA + N-acetyl-L-leucine
show the reaction diagram
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N-acetyl-Leu-tRNA + H2O = N-acetyl-Leu + tRNA
show the reaction diagram
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N-acetyl-L-leucyl 4-nitroanilide + H2O = N-acetyl-L-leucine + 4-nitroaniline
show the reaction diagram
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N-acetyl-L-leucyl 4-nitroanilide + H2O = N-acetyl-L-leucine + 4-nitroaniline
show the reaction diagram
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N-acetyl-L-leucyl 4-nitroanilide + H2O = N-acetyl-L-leucine + 4-nitroaniline
show the reaction diagram
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acetyl-L-Leu methyl ester + H2O = acetyl-L-Leu + methanol
show the reaction diagram
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acetyl-L-Leu methyl ester + H2O = acetyl-L-Leu + methanol
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

3D Structure of Enzyme-Ligand-Complex (PDB) (2 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for N-acetyl-L-leucine

ChEBI
PubChem
ChEBI
PubChem