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Ligand cumene hydroperoxide

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (10 results)

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Show Natural Substrate (10 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.11.1.9

cumene hydroperoxide + GSH = ?

396644, 396632, 396635, 396638, 396645, 396639, 396640, 396642

-

1.11.2.3

aniline + cumene hydroperoxide = ?

712359

-

1.11.2.3

aniline + cumene hydroperoxide = nitrosobenzene + ?

713295

-

1.11.2.3

linoleic acid + cumene hydroperoxide = ?

712359, 724973

-

1.11.2.3

linolenic acid + cumene hydroperoxide = linolenic acid 9,10-15,16-diepoxide + ?

724973

-

1.11.2.3

methyl 4-tolyl sulfide + cumene hydroperoxide = ?

712359

-

1.11.2.3

oleic acid + cumene hydroperoxide = ?

713275

-

1.11.2.3

oleic acid + cumene hydroperoxide = cis-9,10-epoxystearic acid + ?

712359

-

1.11.2.3

thiobenzamide + cumene hydroperoxide = ?

712359

-

1.11.2.3

8 entries

5.3.99.2

cumene hydroperoxide + 2 GSH = cumene hydroxide + GSSG + H2O

649720

-

Substrate in Enzyme-catalyzed Reactions (57 results)

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Show Substrate (57 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.11.1.11

L-ascorbate + cumene hydroperoxide = ?

711139

-

1.11.1.11

L-ascorbic acid + cumene hydroperoxide = dehydroascorbate + 1,1-dimethylbenzylalcohol + H2O

439858, 439871, 439874, 439867

-

1.11.1.11

p-cresol + cumene-hydroperoxide = 4a,9b-dihydro-8,9b-dimethyl-3(4H)-dibenzofuranone + 2,2'-dihydroxy-5,5'-dimethylbiphenyl + 1,1-dimethylbenzylalcohol + bis-(1-methyl-1-phenylethyl)peroxide

439877

-

1.11.1.12

glutathione + cumene hydroperoxide = ?

394878, 394871, 394880, 701060, 394864, 394865, 394868, 394875, 394882, 394876

-

1.11.1.12

GSH + cumene hydroperoxide = GSSG + ?

659647, 658606

-

1.11.1.20

thioredoxin + cumene hydroperoxide = thioredoxin disulfide + ?

687797

-

1.11.1.20

thioredoxin + cumene hydroperoxide = thioredoxin disulfide + H2O + 2-phenylpropan-2-ol

687797

-

1.11.1.11

3 entries

1.11.1.12

2 entries

1.11.1.20

2 entries

1.11.1.22

cumene hydroperoxide + NADPH + H+ = ? + NADP+ + H2O

722255

-

1.11.1.24

2 thioredoxin + cumene hydroperoxide = thioredoxin disulfide + H2O + 2-phenylpropan-2-ol

711784, 711785, 712427, 713425

-

1.11.1.24

cumene hydroperoxide + dithiothreitol = 2-phenylpropan-2-ol + oxidized dithiothreitol

684691, 745231

-

1.11.1.24

cumene hydroperoxide + reduced dithiothreitol = 2-phenylpropan-2-ol + oxidized dithiothreitol

687541

-

1.11.1.24

cumene hydroperoxide + reduced thioredoxin = 2-phenylpropan-2-ol + oxidized thioredoxin + H2O

687610, 676508, 686887, 689812, 698025

-

1.11.1.24

cumene hydroperoxide + reduced thioredoxin = ?

675585, 673665

-

1.11.1.24

cumene hydroperoxide + tryparedoxin 2 = 2-phenylpropan-2-ol + oxidized tryparedoxin 2

655661

-

1.11.1.24

thioredoxin + cumene hydroperoxide = thioredoxin disulfide + H2O + cumene hydroxide

752698

-

1.11.1.24

thioredoxin A + cumene hydroperoxide = thioredoxin A disulfide + H2O + cumene hydroxide

754009

-

1.11.1.24

8 entries

1.11.1.25

cumene hydroperoxide + reduced glutaredoxin = 2-phenylpropan-2-ol + oxidized glutaredoxin

656927

-

1.11.1.26

NADH + cumene hydroperoxide + H+ = ?

765064, 764731

-

1.11.1.27

cumene hydroperoxide + GSH = 2-phenylpropan-2-ol + GSSG

673786

-

1.11.1.28

a [lipoyl-carrier protein]-N6-[(R)-dihydrolipoyl]-L-lysine + cumene hydroperoxide = a [lipoyl-carrier protein]-N6-lipoyl-L-lysine + H2O + cumene hydroxide

754057, 754070

-

1.11.1.28

cumene hydroperoxide + dihydrolipoamide = 2-phenylpropan-2-ol + lipoamide

758317

-

1.11.1.28

cumene hydroperoxide + dithiothreitol = 2-phenylpropan-2-ol + oxidized dithiothreitol

758317

-

1.11.1.7

2,2'-azino-bis-(3-ethylbenzthiazole-6-sulfonic acid) + cumene hydroperoxide = ?

701107

-

1.11.1.7

AmplexRed + cumene hydroperoxide = ?

686088

-

1.11.1.7

reduced thioredoxin 1 + cumene hydroperoxide = oxidized thioredoxin 1 + cumene hydroxide

659307

-

1.11.1.9

2 glutathione + cumene hydroperoxide = glutathione disulfide + 2-phenylpropan-2-ol + H2O

764281, 764056

-

1.11.1.9

cumene hydroperoxide + 2 2-nitro-5-sulfanylbenzoic acid = 2-phenylpropan-2-ol + 3,3'-disulfanediylbis(6-nitrobenzoic acid) + H2O

742280

-

1.11.1.9

cumene hydroperoxide + 2 4-nitrobenzenethiol = 2-phenylpropan-2-ol + 1,1'-disulfanediylbis(4-nitrobenzene) + H2O

742280

-

1.11.1.9

cumene hydroperoxide + 2 GSH = 2-phenylpropan-2-ol + GSSG + H2O

758029, 743785, 741798, 742280, 743399, 742015

-

1.11.1.9

cumene hydroperoxide + 2-nitro-5-sulfanylbenzoic acid = 2-phenylpropan-2-ol + 3,3'-disulfanediylbis(6-nitrobenzoic acid) + H2O

741798

-

1.11.1.9

cumene hydroperoxide + GSH = 2-phenylpropan-2-ol + GSSG + H2O

659416, 658820

-

1.11.1.9

cumene hydroperoxide + GSH = ?

396644, 396607, 396632, 690043, 396635, 396638, 396645, 690120, 396639, 396640, 396642

-

1.11.1.9

cumene hydroperoxide + H2O2 = ?

685411

-

1.11.1.9

glutathione + cumene hydroperoxide = ?

701160

-

1.11.2.3

10-cis-heptadecenoic acid + cumene hydroperoxide = 10,11-epoxyheptadecanoic acid + ?

726222

-

1.11.2.3

10-cis-pentadecenoic acid + cumene hydroperoxide = 10,11-epoxypentadecanoic acid + ?

726222

-

1.11.2.3

9-cis-hexadecenoic acid + cumene hydroperoxide = 9,10-epoxy hexadecanoic acid + ?

726222

-

1.11.2.3

aniline + cumene hydroperoxide = ?

712359

-

1.11.2.3

aniline + cumene hydroperoxide = N-phenylhydroxylamine + H2O

743492

-

1.11.2.3

aniline + cumene hydroperoxide = nitrosobenzene + ?

713295

-

1.11.2.3

linoleic acid + cumene hydroperoxide = ?

712359, 743492, 724973, 726222

-

1.11.2.3

linolenic acid + cumene hydroperoxide = ?

743492

-

1.11.2.3

linolenic acid + cumene hydroperoxide = linolenic acid 9,10-15,16-diepoxide + ?

724973

-

1.11.2.3

methyl 4-tolyl sulfide + cumene hydroperoxide = ?

712359

-

1.11.2.3

oleic acid + cumene hydroperoxide = ?

713275, 765808, 743492, 726222

-

1.11.2.3

oleic acid + cumene hydroperoxide = cis-9,10-epoxystearic acid + ?

712359

-

1.11.2.3

palmitic acid + cumene hydroperoxide = ?

765808

-

1.11.2.3

parathion ethyl + cumene hydroperoxide = paraoxon + ?

713275

-

1.11.2.3

thiobenzamide + cumene hydroperoxide = ?

712359

-

1.11.1.28

3 entries

1.11.1.7

3 entries

1.11.1.9

9 entries

1.11.2.3

15 entries

1.11.2.4

myristic acid + cumene hydroperoxide = ?

710994

-

1.21.4.2

dithiothreitol + cumene hydroperoxide = ?

671651

-

2.5.1.18

cumene hydroperoxide + glutathione = ?

702461, 702404, 704632, 738406, 739246, 704872, 737769, 737761

-

2.5.1.18

cumene hydroperoxide + GSH = ?

661414, 661699, 661527, 660795

-

2.5.1.18

glutathione + cumene hydroperoxide = ?

637906, 637907, 637911, 637913, 637920, 671828, 637893, 637908, 637914, 637918, 637934, 637912, 637937, 637956, 396634, 637951, 701576, 637943, 684978, 686225, 684236, 684726, 706266, 759301, 759268, 759345, 760092, 637892, 684841, 759912, 759011

-

5.3.99.2

cumene hydroperoxide + 2 GSH = cumene hydroxide + GSSG + H2O

649720

-

5.3.99.2

cumene hydroperoxide = cumene hydroxide

649654

-

2.5.1.18

3 entries

5.3.99.2

2 entries

5.3.99.3

cumene hydroperoxide + 2 GSH = cumene hydroxide + GSSG + H2O

652399

-

Activator in Enzyme-catalyzed Reactions (1 result)

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Show Activating Compound (1 entry)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

1.14.15.1

considerable amount of the putative Cpd II species accumulates, even at pH 7.4. By contrast, reactions with meta-chloroperbenzoic acid at pH 7.4 yield very little of the ca. 420 nm species, unless methanol is included

704713

-

Inhibitor in Enzyme-catalyzed Reactions (8 results)

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Show Inhibitors (8 entries)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

1.1.1.49

1% residual activity after treatment with 17 mM cumene hydroperoxide at 50°C and pH 7 for 2 h

678997

-

1.11.1.20

competitive inhibition of prostamide F synthase activity

687797

-

1.14.99.15

-

438348

-

1.8.4.15

-

763778

-

2.5.1.18

2.5 mM, 43.3% inhibition of wild-type enzyme, 27% of mutant enzyme H144A, 50.6% of mutant enzyme V147A, 41.5% of mutant enzyme V147L, 48.1% of mutant enzyme R96A

661886

-

2.7.1.40

1% residual activity after treatment with 17 mM cumene hydroperoxide at 50°C and pH 7 for 2 h

678997

-

4.2.1.11

1% residual activity after treatment with 17 mM cumene hydroperoxide at 50°C and pH 7 for 2 h

678997

-

5.3.4.1

-

763778

-

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (26 results)

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Show Turnover Number (26 entries)

EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

1.11.1.20

0.1

-

in 0.1 M KPB (pH 7.0), at 24°C

687797

1.11.1.20

0.1

-

pH 7.0, 24°C

687797

1.11.1.24

0.274

-

PrxT, in 50 mM HEPES/NaOH, pH 7.3, at 25°C

687610

1.11.1.24

0.281

-

PrxQ, in 50 mM HEPES/NaOH, pH 7.3, at 25°C

687610

1.11.1.24

0.41

-

pH 7.4, 37°C, recombinant enzyme

712427

1.11.1.24

6.3

-

22°C, pH 7.0

673665

1.11.1.24

7.3

-

pH 7.0, temperature not specified in the publication, Prx197

711784

1.11.1.24

9.8

-

pH 7.0, 25°C, TpAhpC

713425

1.11.1.24

15.2

-

pH 7.0, temperature not specified in the publication, Prx231

711784

1.11.1.24

52

-

in 50 mM potassium phosphate pH 7.0, at 25°C

689812

1.11.1.20

2 entries

1.11.1.24

8 entries

1.11.1.25

0.9

-

-

656927

1.11.1.26

11.6

-

in the presence of thioredoxin C as reducing system, at pH 7.4 and 25°C

764731

1.11.1.26

29.7

-

in the presence of AhpD as reducing system, at pH 7.4 and 25°C

764731

1.11.1.28

0.033

-

pH 7.0, 25°C

754057

1.11.1.28

0.067

-

pH 7.0, 25°C

754057

1.11.1.7

70.1

-

25°C, pH 7.0

659307

1.11.1.7

330

-

in 50 mM potassium phosphate buffer, pH 7.0

701107

2.5.1.18

0.0007

-

mutant enzyme N24A, pH and temperature not specified in the publication

759345

2.5.1.18

0.21

-

wild type enzyme, pH and temperature not specified in the publication

759345

2.5.1.18

0.27

-

isoform GSTU45, pH not specified in the publication, at 30°C

737761

2.5.1.18

0.58

-

isoform GSTU16, pH not specified in the publication, at 30°C

737761

2.5.1.18

9.03

-

at pH 7.0, temperature not specified in the publication

759011

2.5.1.18

200

-

30°C, mutant enzyme Y108A

661414

2.5.1.18

2700

-

30°C, mutant enzyme Y108W

661414

2.5.1.18

8100

-

30°C, mutant enzyme Y108F

661414

2.5.1.18

9600

-

30°C, wild-type enzyme

661414

1.11.1.26

2 entries

1.11.1.28

2 entries

1.11.1.7

2 entries

2.5.1.18

9 entries

K_M Value (40 results)

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Show KM Value (40 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

1.11.1.12

0.0017

-

recombinant enzyme

394875

1.11.1.12

0.119

-

-

658606

1.11.1.12

608

-

-

658606

1.11.1.20

0.026

-

in 0.1 M KPB (pH 7.0), at 24°C

687797

1.11.1.20

0.026

-

pH 7.0, 24°C

687797

1.11.1.24

0.00665

-

PrxT, in 50 mM HEPES/NaOH, pH 7.3, at 25°C

687610

1.11.1.24

0.00848

-

PrxQ, in 50 mM HEPES/NaOH, pH 7.3, at 25°C

687610

1.11.1.24

0.0096

-

pH 7.0, 25°C, TpAhpC

713425

1.11.1.24

0.0127

-

22°C, pH 7.0

673665

1.11.1.24

0.037

-

pH 7.4, 37°C, recombinant enzyme

712427

1.11.1.24

0.107

-

in 50 mM potassium phosphate pH 7.0, at 25°C

689812

1.11.1.24

0.152

-

pH 7.0, temperature not specified in the publication, Prx231

711784

1.11.1.24

0.191

-

pH 7.0, temperature not specified in the publication, Prx197

711784

1.11.1.26

0.0692

-

in the presence of AhpD as reducing system, at pH 7.4 and 25°C

764731

1.11.1.26

0.1473

-

in the presence of thioredoxin C as reducing system, at pH 7.4 and 25°C

764731

1.11.1.12

3 entries

1.11.1.20

2 entries

1.11.1.24

8 entries

1.11.1.26

2 entries

1.11.1.27

0.12

-

-

673786

1.11.1.28

0.052

-

pH 7.0, 25°C

754057

1.11.1.28

0.55

-

pH 7.0, 25°C

754057

1.11.1.7

0.009

-

25°C, pH 7.0

659307

1.11.1.7

3

-

in 50 mM potassium phosphate buffer, pH 7.0

701107

1.11.1.9

0.006

-

-

396607

1.11.1.9

0.111

-

-

396642

1.11.1.9

0.144

-

-

396612

1.11.1.9

0.145

-

pH 8.0, 30°C

758029

1.11.1.9

0.26

-

-

396640

1.11.1.9

7.8

-

pH 7.5, 25°C

659416

1.11.2.4

0.11

-

mutant enzyme R242A, using myristic acid as cosubstrate, in 0.1 M potassium phosphate buffer (pH 6.7), at 25°C

710994

1.11.2.4

0.2

-

wild type enzyme, using myristic acid as cosubstrate, in 0.1 M potassium phosphate buffer (pH 6.7), at 25°C

710994

1.11.2.4

0.24

-

mutant enzyme R242K, using myristic acid as cosubstrate, in 0.1 M potassium phosphate buffer (pH 6.7), at 25°C

710994

2.5.1.18

0.038

-

isoform GSTU16, pH not specified in the publication, at 30°C

737761

2.5.1.18

0.11

-

wild type enzyme, pH and temperature not specified in the publication

759345

2.5.1.18

0.252

-

at pH 6.5 and 25°C

737769

2.5.1.18

0.3

-

30°C, wild-type enzyme

661414

2.5.1.18

0.439

-

pH and temperature not specified in the publication

738406

2.5.1.18

0.9

-

30°C, mutant enzyme Y108W

661414

2.5.1.18

2.11

-

30°C, mutant enzyme Y108F

661414

2.5.1.18

4.853

-

isoform GSTU45, pH not specified in the publication, at 30°C

737761

2.5.1.18

5.3

6

mutant enzyme N24A, pH and temperature not specified in the publication

759345

2.5.1.18

8

-

30°C, mutant enzyme Y108A

661414

2.5.1.18

14.3

-

at pH 7.0, temperature not specified in the publication

759011

1.11.1.28

2 entries

1.11.1.7

2 entries

1.11.1.9

6 entries

1.11.2.4

3 entries

2.5.1.18

11 entries

References & Links

Literature References (131)

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Show Reference (131 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

394864

3978121

The selenoenzyme phospholipid hydroperoxide glutathione peroxidase

1985

Ursini, F.; Maiorini, M.; Gregolin, C.

Biochim. Biophys. Acta

839

62-70

394865

3800387

Different effects of Triton X-100, deoxycholate, and fatty acids on the kinetics of glutathione peroxidase and phospholipid hydroperoxide glutathione peroxidase

1986

Maiorino, M.; Roveri, A.; Gregolin, C.; Ursini, F.

Arch. Biochem. Biophys.

251

600-605

394868

7066358

Purification from pig liver of a protein which protects liposomes and biomembranes from peroxidative degradation and exhibits glutathione peroxidase activity on phosphatidylcholine hydroperoxides

1982

Ursini, F.; Maiorino, M.; Valente, M.; Ferri, L.; Gregolin, C.

Biochim. Biophys. Acta

710

197-211

394871

2804065

Phospholipid hydroperoxide glutathione peroxidase: specific activity in tissues of rats of different age and comparison with other glutathione peroxidases

1989

Zhang, L.; Maiorini, M.; Roveri, A.; Ursini, F.

Biochim. Biophys. Acta

1006

140-143

394875

11104683

Biochemical characterization of a trypanosome enzyme with glutathione-dependent peroxidase activity

2000

Wilkinson, S.R.; Meyer, D.J.; Kelly, J.M.

Biochem. J.

352

755-761

394876

8436014

Purification of phospholipid hydroperoxide glutathione peroxidase from bovine retina

1993

Lam, K.W.; Wang, L.; Hong, B.S.; Treble, D.

Curr. Eye Res.

12

9-15

394878

7851631

Purification of a cytosolic enzyme from human liver with phospholipid hydroperoxide glutathione peroxidase activity

1994

Chambers, S.J.; Lambert, N.; Williamson, G.

Int. J. Biochem.

26

1279-1286

394880

7524677

Purification and characterization of phospholipid hydroperoxide glutathione peroxidase from rat testis mitochondrial membranes

1994

Roveri, A.; Maiorino, M.; Nisii, C.; Ursini, F.

Biochim. Biophys. Acta

1208

211-221

394882

8706688

A selenium-containing phospholipid-hydroperoxide glutathione peroxidase in Schistosoma mansoni

1996

Maiorino, M.; Roche, C.; Kiess, M.; Koenig, K.; Gawlik, D.; Matthes, M.; Naldini, E.; Pierce, R.; Flohe, L.

Eur. J. Biochem.

238

838-844

396607

6882790

Selenium-dependent and non-selenium-dependent glutathione peroxidases in human tissue extracts

1983

Charmagnol, F.; Sinet, P.M.; Jerome, H.

Biochim. Biophys. Acta

759

49-57

396612

6986175

Purification and immunohistochemical localization of rat liver glutathione peroxidase

1980

Yoshimura, S.; Komatsu, N.; Watanabe, K.

Biochim. Biophys. Acta

621

130-137

396632

8428933

Expression, characterization, and tissue distribution of a new cellular selenium-dependent glutathione peroxidase, GSHPx-GI

1993

Chu, F.F.; Doroshow, J.H.; Esworthy, R.S.

J. Biol. Chem.

268

2571-2576

396634

-

Characterization of glutathione transferases and glutathione peroxidases in pea (Pisum sativum)

1996

Edwards, R.

Physiol. Plant.

98

594-604

396635

9030530

Subunit Ya-specific glutathione peroxidase activity toward cholesterol 7-hydroperoxides of glutathione S-transferases in cytosols from rat liver and skin

1997

Hiratsuka, A.; Yamane, H.; Yamazaki, S.; Ozawa, N.; Watabe, T.

J. Biol. Chem.

272

4763-4769

396638

12215683

Nuclear and nucleolar glutathione reductase, peroxidase, and transferase activities in livers of male and female Fischer-344 Rats

2002

Rogers, L.K.; Gupta, S.; Welty, S.E.; Hansen, T.N.; Smith, C.V.

Toxicol. Sci.

69

279-285

396639

8926102

Expression and characterization of glutathione peroxidase activity in the human blood fluke Schistosoma mansoni

1996

Mei, H.; Thakur, A.; Schwartz, J.; Lo Verde, P.T.

Infect. Immun.

64

4299-4306

396640

8193675

Purification and characterization of a glutathione peroxidase from the Aloe vera plant

1994

Sabeh, F.; Wright, T.; Norton, S.J.

Enzyme Protein

47

92-98

396642

11926531

Glutathione peroxidase from the liver of Japanese sea bass Lateolabrax japonicus

2002

Nagai, T.; Yukimoto, T.; Suzuki, N.

Z. Naturforsch. C

57

172-176

396644

8842471

Purification and characterisation of chicken liver monomeric glutathione peroxidase

1996

Miyazaki, S.; Motoi, Y.

Br. Poult. Sci.

37

651-660

396645

7986075

Demonstration of glutathione peroxidase in rat liver peroxisomes and its intraorganellar distribution

1994

Singh, A.K.; Dhaunsi, G.S.; Gupta, M.P.; Orak, J.K.; Asayama, K.; Singh, I.

Arch. Biochem. Biophys.

315

331-338

438348

188654

Kinetic studies on a 4-methoxybenzoate O-demethylase from Pseudomonas putida

1977

Bernhardt, F.H.; Nastainczyk, W.; Seydewitz, U.

Eur. J. Biochem.

72

107-115

439858

6772104

Purification and some properties of L-ascorbic-acid-specific peroxidase in Euglena gracilis Z

1980

Shigeoka, S.; Nahana, Y.; Kitaoka, S.

Arch. Biochem. Biophys.

201

121-127

439867

-

Ascorbate peroxidase: a novel antioxidant enzyme in insects

1997

Mathews, M.C.; Summers, C.B.; Felton, G.W.

Arch. Insect Biochem. Physiol.

34

57-68

439871

9672748

Purification and characterization of ascorbate peroxidase in Chlorella vulgaris

1998

Takeda, T.; Yoshimura, K.; Ishikawa, T.; Shigeoka, S.

Biochimie

80

295-301

439874

10729193

Molecular characterization and physiological role of ascorbate peroxidase from halotolerant Chlamydomonas sp. W80 strain

2000

Takeda, T.; Yoshimura, K.; Yoshii, M.; Kanahoshi, H.; Miyasaka, H.; Shigeoka, S.

Arch. Biochem. Biophys.

376

82-90

439877

11356136

Engineering the active site of ascorbate peroxidase

2001

Lloyd Raven, E.; Celik, A.; Cullis, P.M.; Sangar, R.; Sutcliffe, M.J.

Biochem. Soc. Trans.

29

105-111

637892

3091071

Purification and characterization of three distinct glutathione transferases from mouse liver

1986

Warholm, M.; Jensson, H.; Tahir, M.K.; Mannervik, B.

Biochemistry

25

4119-4125

637893

6884349

Microsomal glutathione transferase. Purification in unactivated form and further characterization of the activation process, substrate specificity and amino acid composition

1983

Morgenstern, R.; DePierre, J.W.

Eur. J. Biochem.

134

591-597

637906

7329301

Glutathione transferase (human placenta)

1981

Mannervik, B.; Guthenberg, C.

Methods Enzymol.

77

231-235

637907

3092805

Two distinct forms of glutathione transferase from human foetal liver. Purification and comparison with isoenzymes isolated from adult liver and placenta

1986

Guthenberg, C.; Warholm, M.; Rane, A.; Mannervik, B.

Biochem. J.

235

741-745

637908

3977929

Differences in the occurrence of glutathione transferase isoenzymes in rat lung and liver

1985

Robertson, I.G.C.; Jensson, H.; Guthenberg, C.; Tahir, M.K.; Jernström, B.; Mannervik, B.

Biochem. Biophys. Res. Commun.

127

80-86

637911

3663118

Characterization of the basic glutathione S-transferase B1 and B2 subunits from human liver

1987

Stockman, P.K.; McLellan, L.I.; Hayes, J.D.

Biochem. J.

244

55-61

637912

-

The purification of multiple forms of glutathione S-transferase from pig liver and their reaction with individual methyl linoleate hydroperoxides

1986

Williamson, G.; Ball, S.K.M.; Chan, H.W.C.

Biochem. Soc. Trans.

14

1278-1279

637913

4044571

Isolation and characterization of the multiple glutathione S-transferases from human liver. Evidence for unique heme-binding sites

1985

Vander Jagt, D.L.; Hunsaker, L.A.; Garcia, K.B.; Royer, R.E.

J. Biol. Chem.

260

11603-11610

637914

4025799

Purification of major basic glutathione transferase isoenzymes from rat liver by use of affinity chromatography and fast protein liquid chromatofocusing

1985

Alin, P.; Jensson, H.; Guthenberg, C.; Danielson, U.H.; Tahir, M.K.; Mannervik, B.

Anal. Biochem.

146

313-320

637918

6743313

Identification of a new glutathione S-transferase from rat liver cytosol

1984

Reddy, C.C.; Li, N.Q.; Tu, C.P.D.

Biochem. Biophys. Res. Commun.

121

1014-1020

637920

6517933

Purification and characterization of a new form of glutathione S-transferase from human erythrocytes

1984

Awasthi, Y.C.; Singh, S.V.

Biochem. Biophys. Res. Commun.

125

1053-1060

637934

6838589

Isolation and characterization of an anionic glutathione S-transferase from rat liver cytosol

1983

Reddy, C.C.; Burgess, J.R.; Tu, C.P.D.

Biochem. Biophys. Res. Commun.

111

840-846

637937

6870266

Purification and characterization of the individual glutathione S-transferases from sheep liver

1983

Reddy, C.C.; Burgess, J.R.; Gong, Z.Z.; Massaro, E.J.; Tu, C.P.D.

Arch. Biochem. Biophys.

224

87-101

637943

-

Purification and characterization of two glutathione S-transferase isozymes from Indica-type rice involved in herbicide detoxification

2002

Deng, F.; Hatzios, K.K.

Pestic. Biochem. Physiol.

72

10-23

637951

-

Structural and functional analysis of a glutathione S-transferase from Ascaris sum

1997

Liebau, E.; Eckelt, V.H.O.; Wildenburg, G.; Teesdale-Spittle, P.; Brophy, P.M.; Walter, R.D.; Henkle-Duhrsen, K.

Biochem. J.

324

659-666

637956

-

Cloning and characterization of a glutathione S-transferase induced by a herbicide safener in barley (Hordeum vulgare)

2002

Scalla, R.; Roulet, A.

Physiol. Plant.

116

336-344

649654

-

Sequence, catalytic properties and expression of chicken glutathione-dependent prostaglandin D2 synthase, a novel class sigma glutathione S-transferase

1998

Thomson, A.M.; Meyer, D.J.; Hayes, J.D.

Biochem. J.

333

317-325

649720

11672424

Mammalian class Sigma glutathione S-transferases: catalytic properties and tissue-specific expression of human and rat GSH-dependent prostaglandin D2 synthases

2001

Jowsey, I.R.; Thomson, A.M.; Flanagan, J.U.; Murdock, P.R.; Moore, G.B.T.; Meyer, D.J.; Murphy, G.J.; Smith, S.A.; Hayes, J.D.

Biochem. J.

359

507-516

652399

12672824

Human microsomal prostaglandin E synthase-1: purification, functional characterization, and projection structure determination

2003

Thoren, S.; Weinander, R.; Saha, S.; Jegerschoeld, C.; Pettersson, P.L.; Samuelsson, B.; Hebert, H.; Hamberg, M.; Morgenstern, R.; Jakobsson, P.J.

J. Biol. Chem.

278

22199-22209

655661

12446214

Specificity and kinetics of a mitochondrial peroxiredoxin of Leishmania infantum

2002

Castro, H.; Budde, H.; Flohe, L.; Hofmann, B.; Lunsdorf, H.; Wissing, J.; Tomas, A.M.

Free Radic. Biol. Med.

33

1563-1574

656927

15032877

Active site mutagenesis and phospholipid hydroperoxide reductase activity of poplar type II peroxiredoxin

2004

Rouhier, N.; Gelhaye, E.; Corbier, C.; Jacquot, J.P.

Physiol. Plant.

120

57-62

658606

11985625

Two GPX-like proteins from Lycopersicon esculentum and Helianthus annuus are antioxidant enzymes with phospholipid hydroperoxide glutathione peroxidase and thioredoxin peroxidase activities

2002

Herbette, S.; Lenne, C.; Leblanc, N.; Julien, J.L.; Drevet, J.R.; Roeckel-Drevet, P.

Eur. J. Biochem.

269

2414-2420

658820

14693370

Glutathione peroxidases of the potato cyst nematode Globodera rostochiensis

2004

Jones, J.T.; Reavy, B.; Smant, G.; Prior, A.E.

Gene

324

47-54

659307

12514184

Catalytic mechanism of thiol peroxidase from Escherichia coli: Sulfenic acid formation and overoxidation of essential Cys61

2003

Baker, L.M.S.; Poole, L.B.

J. Biol. Chem.

278

9203-9211

659416

15371425

The yeast prion protein Ure2 shows glutathione peroxidase activity in both native and fibrillar forms

2004

Bai, M.; Zhou, J.M.; Perrett, S.

J. Biol. Chem.

279

50025-50030

659647

12770011

Possible function of two insect phospholipid-hydroperoxide glutathione peroxidases

2003

Li, D.; Blasevich, F.; Theopold, U.; Schmidt, O.

J. Insect Physiol.

49

1-9

660795

15019838

Characterization of a class alpha glutathione-S-transferase with glutathione peroxidase activity in human liver microsomes

2004

Prabhu, K.S.; Reddy, P.V.; Jones, E.C.; Liken, A.D.; Reddy, C.C.

Arch. Biochem. Biophys.

424

72-80

661414

-

Functional studies of tyrosine 108 residue in the active site of human glutathione S-transferase P1-1

2005

Park, H.J.; Koh, J.U.; Ahn, S.Y.; Kong, K.H.

Bull. Korean Chem. Soc.

26

433-439

661527

15556070

Glutathione S-transferase in the insect Apis mellifera macedonica kinetic characteristics and effect of stress on the expression of GST isoenzymes in the adult worker bee

2004

Papadopoulos, A.I.; Polemitou, I.; Laifi, P.; Yiangou, A.; Tananaki, C.

Comp. Biochem. Physiol. C

139

93-97

661699

16008560

Purification and properties of the glutathione S-transferases from the anoxia-tolerant turtle,Trachemys scripta elegans

2005

Willmore, W.G.; Storey, K.B.

FEBS J.

272

3602-3614

661886

15705499

Intra-subunit residue interactions from the protein surface to the active site of glutathione S-transferase AdGSTD3-3 impact on structure and enzyme properties

2005

Wongtrakul, J.; Sramala, I.; Prapanthadara, L.A.; Ketterman, A.J.

Insect Biochem. Mol. Biol.

35

197-205

671651

17009022

Peroxidase activity of selenoprotein GrdB of glycine reductase and stabilisation of its integrity by components of proprotein GrdE from Eubacterium acidaminophilum

2007

Groebe, T.; Reuter, M.; Gursinsky, T.; Soehling, B.; Andreesen, J.R.

Arch. Microbiol.

187

29-43

671828

15683365

Residue 234 in glutathione transferase T1-1 plays a pivotal role in the catalytic activity and the selectivity against alternative substrates

2005

Shokeer, A.; Larsson, A.K.; Mannervik, B.

Biochem. J.

388

387-392

673665

16938293

Biochemical characterisation of the recombinant peroxiredoxin (FhePrx) of the liver fluke, Fasciola hepatica

2006

Sekiya, M.; Mulcahy, G.; Irwin, J.A.; Stack, C.M.; Donnelly, S.M.; Xu, W.; Collins, P.; Dalton, J.P.

FEBS Lett.

580

5016-5022

673786

15890616

Peroxiredoxin 6, a 1-Cys peroxiredoxin, functions in antioxidant defense and lung phospholipid metabolism

2005

Manevich, Y.; Fisher, A.B.

Free Radic. Biol. Med.

38

1422-1432

675585

16995398

Molecular cloning and characterization of a 2-Cys peroxiredoxin from Taenia solium

2006

Molina-Lopez, J.; Jimenez, L.; Ochoa-Sanchez, A.; Landa, A.

J. Parasitol.

92

796-802

676508

16507087

Peroxiredoxin Q of Arabidopsis thaliana is attached to the thylakoids and functions in context of photosynthesis

2006

Lamkemeyer, P.; Laxa, M.; Collin, V.; Li, W.; Finkemeier, I.; Schoettler, M.A.; Holtkamp, V.; Tognetti, V.B.; Issakidis-Bourguet, E.; Kandlbinder, A.; Weis, E.; Miginiac-Maslow, M.; Dietz, K.J.

Plant J.

45

968-981

678997

9741972

Inactivation of enzymes within spores of Bacillus megaterium ATCC 19213 by hydroperoxides

1998

Palop, A.; Rutherford, G.C.; Marquis, R.E.

Can. J. Microbiol.

44

465-470

684236

17897613

Glutathione transferases from parasites: a biochemical view

2008

Torres-Rivera, A.; Landa, A.

Acta Trop.

105

99-112

684691

17892856

Pre-steady state kinetic characterization of human peroxiredoxin 5: taking advantage of Trp84 fluorescence increase upon oxidation

2007

Trujillo, M.; Clippe, A.; Manta, B.; Ferrer-Sueta, G.; Smeets, A.; Declercq, J.P.; Knoops, B.; Radi, R.

Arch. Biochem. Biophys.

467

95-106

684726

18662665

Cooperative kinetics of the recombinant glutathione transferase of Taenia solium and characterization of the enzyme

2008

Torres-Rivera, A.; Landa, A.

Arch. Biochem. Biophys.

477

372-378

684841

17367761

MALDI mass sequencing and characterization of filarial glutathione-S-transferase

2007

Gupta, S.; Singh, A.; Yadav, M.; Singh, K.; Rathaur, S.

Biochem. Biophys. Res. Commun.

356

381-385

684978

17484723

Novel class of glutathione transferases from cyanobacteria exhibit high catalytic activities towards naturally occurring isothiocyanates

2007

Wiktelius, E.; Stenberg, G.

Biochem. J.

406

115-123

685411

17544198

Cytosolic glutathione peroxidase from liver of pacu (Piaractus mesopotamicus), a hypoxia-tolerant fish of the Pantanal

2007

Cunha Bastos, V.L.; Salles, J.B.; Valente, R.H.; Leon, I.R.; Perales, J.; Dantas, R.F.; Albano, R.M.; Bastos, F.F.; Cunha Bastos, J.

Biochimie

89

1332-1342

686088

18157853

Characterization of the peroxidase activity of CYP119, a thermostable P450 from Sulfolobus acidocaldarius

2008

Rabe, K.S.; Kiko, K.; Niemeyer, C.M.

Chembiochem

9

420-425

686225

18752976

Purification and biochemical characterization of cytosolic glutathione-S-transferase from filarial worms Setaria cervi

2008

Ahmad, R.; Srivastava, A.K.; Walter, R.D.

Comp. Biochem. Physiol. B

151

237-245

686887

18503776

Cloning and characterization of Arenicola marina peroxiredoxin 6, an annelid two-cysteine peroxiredoxin highly homologous to mammalian one-cysteine peroxiredoxins

2008

Loumaye, E.; Andersen, A.C.; Clippe, A.; Degand, H.; Dubuisson, M.; Zal, F.; Morsomme, P.; Rees, J.F.; Knoops, B.

Free Radic. Biol. Med.

45

482-493

687541

17329258

The high reactivity of peroxiredoxin 2 with H(2)O(2) is not reflected in its reaction with other oxidants and thiol reagents

2007

Peskin, A.V.; Low, F.M.; Paton, L.N.; Maghzal, G.J.; Hampton, M.B.; Winterbourn, C.C.

J. Biol. Chem.

282

11885-11892

687610

17644813

The significance of type II and PrxQ peroxiredoxins for antioxidative stress response in the purple bacterium Rhodobacter sphaeroides

2007

Wakita, M.; Masuda, S.; Motohashi, K.; Hisabori, T.; Ohta, H.; Takamiya, K.

J. Biol. Chem.

282

27792-27801

687797

18006499

Molecular characterization of a novel type of prostamide/prostaglandin F synthase, belonging to the thioredoxin-like superfamily

2008

Moriuchi, H.; Koda, N.; Okuda-Ashitaka, E.; Daiyasu, H.; Ogasawara, K.; Toh, H.; Ito, S.; Woodward, D.F.; Watanabe, K.

J. Biol. Chem.

283

792-801

689812

18165315

Substrate specificity and redox potential of AhpC, a bacterial peroxiredoxin

2008

Parsonage, D.; Karplus, P.A.; Poole, L.B.

Proc. Natl. Acad. Sci. USA

105

8209-8214

690043

17558897

Elevated plasma glutathione peroxidase concentration in acute severe asthma: comparison with plasma glutathione peroxidase activity, selenium and malondialdehyde

2007

Jacobson, G.A.; Yee, K.C.; Ng, C.H.

Scand. J. Clin. Lab. Invest.

67

423-430

690120

17964641

Localization and characterization of glutathione peroxidase (GPx) in boar accessory sex glands, seminal plasma, and spermatozoa and activity of GPx in boar semen

2008

Jelezarsky, L.; Vaisberg, C.h.; Chaushev, T.; Sapundjiev, E.

Theriogenology

69

139-145

698025

19460442

Molecular cloning, characterization and expression analysis of peroxiredoxin 6 from disk abalone Haliotis discus discus and the antioxidant activity of its recombinant protein

2009

Nikapitiya, C.; De Zoysa, M.; Whang, I.; Kim, C.G.; Lee, Y.H.; Kim, S.J.; Lee, J.

Fish Shellfish Immunol.

27

239-249

701060

18723092

New strategies for the isolation and activity determination of naturally occurring type-4 glutathione peroxidase

2008

Kernstock, R.M.; Girotti, A.W.

Protein Expr. Purif.

62

216-222

701107

19827095

The structure and peroxidase activity of a 33kD catalase-related protein from Mycobacterium avium ssp. paratuberculosis

2009

Pakhomova, S.; Gao, B.; Boeglin, W.E.; Brash, A.R.; Newcomer, M.E.

Protein Sci.

18

2559-2568

701160

19171040

Red blood cell glutathione peroxidase activity in female nulligravid and pregnant rats

2009

Gallo, G.; Martino, G.

Reprod. Biol. Endocrinol.

7

7-7

701576

20034460

Biochemical analysis of a recombinant glutathione transferase from the cestode Echinococcus granulosus

2010

Harispe, L.; Garcia, G.; Arbildi, P.; Pascovich, L.; Chalar, C.; Zaha, A.; Fernandez, C.; Fernandez, V.

Acta Trop.

114

31-36

702404

18706975

Emergence of a novel highly specific and catalytically efficient enzyme from a naturally promiscuous glutathione transferase

2008

Blikstad, C.; Shokeer, A.; Kurtovic, S.; Mannervik, B.

Biochim. Biophys. Acta

1780

1458-1463

702461

20097269

Residue 234 is a master switch of the alternative-substrate activity profile of human and rodent theta class glutathione transferase T1-1

2010

Shokeer, A.; Mannervik, B.

Biochim. Biophys. Acta

1800

466-473

704632

19171936

The glutathione system of Aspergillus nidulans involves a fungus-specific glutathione S-transferase

2009

Sato, I.; Shimizu, M.; Hoshino, T.; Takaya, N.

J. Biol. Chem.

284

8042-8053

704713

18273651

Replacement of tyrosine residues by phenylalanine in cytochrome P450cam alters the formation of Cpd II-like species in reactions with artificial oxidants

2008

Spolitak, T.; Dawson, J.H.; Ballou, D.P.

J. Biol. Inorg. Chem.

13

599-611

704872

19174456

Enzyme activities and subcellular localization of members of the Arabidopsis glutathione transferase superfamily

2009

Dixon, D.P.; Hawkins, T.; Hussey, P.J.; Edwards, R.

J. Exp. Bot.

60

1207-1218

706266

19640724

Biochemical and physiological characterization of a tau class glutathione transferase from rice (Oryza sativa)

2009

Yang, X.; Sun, W.; Liu, J.P.; Liu, Y.J.; Zeng, Q.Y.

Plant Physiol. Biochem.

47

1061-1068

710994

11566026

Site-directed mutagenesis of the putative distal helix of peroxygenase cytochrome P450

2001

Matsunaga, I.; Ueda, A.; Sumimoto, T.; Ichihara, K.; Ayata, M.; Ogura, H.

Arch. Biochem. Biophys.

394

45-53

711139

20015051

Euglena gracilis ascorbate peroxidase forms an intramolecular dimeric structure: its unique molecular characterization

2010

Ishikawa, T.; Tajima, N.; Nishikawa, H.; Gao, Y.; Rapolu, M.; Shibata, H.; Sawa, Y.; Shigeoka, S.

Biochem. J.

426

125-134

711784

20381631

Cloning and functional characterization of a peroxiredoxin 4 from yellowtail kingfish (Seriola lalandi)

2010

Loo, G.H.; Schuller, K.A.

Comp. Biochem. Physiol. B

156

244-253

711785

20211754

Cloning and functional characterization of a typical 2-Cys peroxiredoxin from southern bluefin tuna (Thunnus maccoyii)

2010

Sutton, D.L.; Loo, G.H.; Menz, R.I.; Schuller, K.A.

Comp. Biochem. Physiol. B

156

97-106

712359

16956885

Plant seed peroxygenase is an original heme-oxygenase with an EF-hand calcium binding motif

2006

Hanano, A.; Burcklen, M.; Flenet, M.; Ivancich, A.; Louwagie, M.; Garin, J.; Blee, E.

J. Biol. Chem.

281

33140-33151

712427

20335172

Structural and biochemical characterization of peroxiredoxin Qbeta from Xylella fastidiosa: catalytic mechanism and high reactivity

2010

Horta, B.B.; de Oliveira, M.A.; Discola, K.F.; Cussiol, J.R.; Netto, L.E.

J. Biol. Chem.

285

16051-16065

713275

14535881

Formation of plant cuticle: evidence for the occurrence of the peroxygenase pathway

2003

Lequeu, J.; Fauconnier, M.L.; Chammai, A.; Bronner, R.; Blee, E.

Plant J.

36

155-164

713295

19467604

Roles of a membrane-bound caleosin and putative peroxygenase in biotic and abiotic stress responses in Arabidopsis

2009

Partridge, M.; Murphy, D.J.

Plant Physiol. Biochem.

47

796-806

713425

20304799

Broad specificity AhpC-like peroxiredoxin and its thioredoxin reductant in the sparse antioxidant defense system of Treponema pallidum

2010

Parsonage, D.; Desrosiers, D.C.; Hazlett, K.R.; Sun, Y.; Nelson, K.J.; Cox, D.L.; Radolf, J.D.; Poole, L.B.

Proc. Natl. Acad. Sci. USA

107

6240-6245

722255

11418106

NADPH-dependent glutathione peroxidase-like proteins (Gpx-1, Gpx-2) reduce unsaturated fatty acid hydroperoxides in Synechocystis PCC 6803

2001

Gaber, A.; Tamoi, M.; Takeda, T.; Nakano, Y.; Shigeoka, S.

FEBS Lett.

499

32-36

724973

22913587

A non-canonical caleosin from Arabidopsis efficiently epoxidizes physiological unsaturated fatty acids with complete stereoselectivity

2012

Blee, E.; Flenet, M.; Boachon, B.; Fauconnier, M.L.

FEBS J.

279

3981-3995

726222

21784965

A peroxygenase pathway involved in the biosynthesis of epoxy fatty acids in oat

2011

Meesapyodsuk, D.; Qiu, X.

Plant Physiol.

157

454-463

737761

26026470

Substrate specificities of two tau class glutathione transferases inducible by 2,4,6-trinitrotoluene in poplar

2015

Musdal, Y.; Mannervik, B.

Biochim. Biophys. Acta

1850

1877-1883

737769

25479053

Catalytic features and crystal structure of a tau class glutathione transferase from Glycine max specifically upregulated in response to soybean mosaic virus infections

2015

Skopelitou, K.; Muleta, A.W.; Papageorgiou, A.C.; Chronopoulou, E.; Labrou, N.E.

Biochim. Biophys. Acta

1854

166-177

738406

27103493

Characterization and functional analysis of a recombinant tau class glutathione transferase GmGSTU2-2 from Glycine max

2017

Skopelitou, K.; Muleta, A.W.; Papageorgiou, A.C.; Chronopoulou, E.G.; Pavli, O.; Flemetakis, E.; Skaracis, G.N.; Labrou, N.E.

Int. J. Biol. Macromol.

94 B

802-812

739246

26047112

Functional characterization of glutathione S-transferases associated with insecticide resistance in Tetranychus urticae

2015

Pavlidi, N.; Tseliou, V.; Riga, M.; Nauen, R.; Van Leeuwen, T.; Labrou, N.E.; Vontas, J.

Pestic. Biochem. Physiol.

121

53-60

741798

-

Solvent-dependent catalytic behavior of telluride-containing guest artificial glutathione peroxidase using cumene hydroperoxide and 3-carboxyl-4-nitrobenzenethiol as substrates

2015

Jiao, S.; Yin, Y.; Zhang, R.; Zhong, S.; Wang, X.; Zhang, L.; Yang, L.

Asian J. Chem.

27

2665-2668

742015

27833038

Characterization of glutathione peroxidase diversity in the symbiotic sea anemone Anemonia viridis

2017

Pey, A.; Zamoum, T.; Christen, R.; Merle, P.L.; Furla, P.

Biochimie

132

94-101

742280

25683962

Construction of a artificial glutathione peroxidase with temperature-dependent activity based on a supramolecular graft copolymer

2015

Yin, Y.; Jiao, S.; Wang, Y.; Zhang, R.; Shi, Z.; Hu, X.

ChemBioChem

16

670-676

743399

24477026

Characterization of biochemical properties of a selenium-independent glutathione peroxidase of Cryptosporidium parvum

2014

Kang, J.M.; Ju, H.L.; Sohn, W.M.; Na, B.K.

Parasitology

141

570-578

743492

25056921

The reductase activity of the Arabidopsis caleosin RESPONSIVE TO DESSICATION20 mediates gibberellin-dependent flowering time, abscisic acid sensitivity, and tolerance to oxidative stress

2014

Blee, E.; Boachon, B.; Burcklen, M.; Le Guedard, M.; Hanano, A.; Heintz, D.; Ehlting, J.; Herrfurth, C.; Feussner, I.; Bessoule, J.J.

Plant Physiol.

166

109-124

743785

-

Purification and characterization of two glutathione peroxidases from embryo of the camel tick Hyalomma dromedarii

2016

Ibrahim, M.; Mohamed, M.; Ghazy, A.; El-Mogy, M.; Masoud, H.

Russ. J. Bioorg. Chem.

42

272-281

745231

15625325

Oxidative stress response in an anaerobic hyperthermophilic archaeon Presence of a functional peroxiredoxin in Pyrococcus horikoshii

2004

Kawakami, R.; Sakuraba, H.; Kamohara, S.; Goda, S.; Kawarabayasi, Y.; Ohshima, T.

J. Biochem.

136

541-547

752698

10998352

A novel peroxiredoxin of the plant Sedum lineare is a homologue of Escherichia coli bacterioferritin co-migratory protein Bcp

2000

Kong, W.; Shiota, S.; Shi, Y.; Nakayama, H.; Nakayama, K.

Biochem. J.

351

107-114

754009

19820102

A comprehensive analysis of the peroxiredoxin reduction system in the cyanobacterium Synechocystis sp. strain PCC 6803 reveals that all five peroxiredoxins are thioredoxin dependent

2009

Perez-Perez, M.E.; Mata-Cabana, A.; Sanchez-Riego, A.M.; Lindahl, M.; Florencio, F.J.

J. Bacteriol.

191

7477-7489

754057

10766746

The AhpC and AhpD antioxidant defense system of Mycobacterium tuberculosis

2000

Hillas, P.J.; del Alba, F.S.; Oyarzabal, J.; Wilks, A.; Ortiz De Montellano, P.R.

J. Biol. Chem.

275

18801-18809

754070

12761216

The mechanism of Mycobacterium tuberculosis alkylhydroperoxidase AhpD as defined by mutagenesis, crystallography, and kinetics

2003

Koshkin, A.; Nunn, C.M.; Djordjevic, S.; Ortiz de Montellano, P.R.

J. Biol. Chem.

278

29502-29508

758029

-

A thioredoxin-dependent glutathione peroxidase (OsGPX5) is required for rice normal development and salt stress tolerance

2017

Wang, X.; Fang, G.; Yang, J.; Li, Y.

Plant Mol. Biol. Rep.

35

333-342

758317

28391181

Functional and evolutionary characterization of Ohr proteins in eukaryotes reveals many active homologs among pathogenic fungi

2017

Meireles, D.; Domingos, R.; Gaiarsa, J.; Ragnoni, E.; Bannitz-Fernandes, R.; da Silva Neto, J.; de Souza, R.; Netto, L.

Redox Biol.

12

600-609

759011

27639582

Biochemical characterization of the detoxifying enzyme glutathione transferase P1-1 from the camel Camelus dromedarius

2016

Perperopoulou, F.; Ataya, F.S.; Fouad, D.; Malik, A.; Saeed, H.M.; Labrou, N.E.

Cell Biochem. Biophys.

74

459-472

759268

32308662

Biochemical functions of glutathione S-transferase family of Salix babylonica

2020

Zhuge, X.L.; Xu, H.; Xiu, Z.J.; Yang, H.L.

Front. Plant Sci.

11

364

759301

31878175

Effects of substrate-binding site residues on the biochemical properties of a tau class glutathione S-transferase from Oryza sativa

2019

Yang, X.; Wei, J.; Wu, Z.; Gao, J.

Genes (Basel)

11

25

759345

30928378

Identification of key residues for activities of atypical glutathione S-transferase of Ceriporiopsis subvermispora, a selective degrader of lignin in woody biomass, by crystallography and functional mutagenesis

2019

Osman, W.H.W.; Mikami, B.; Saka, N.; Kondo, K.; Lin, M.I.; Nagata, T.; Katahira, M.

Int. J. Biol. Macromol.

132

222-229

759912

-

Purification of fat body glutathione S-transferase from the desert locust Schistocerca gregaria investigation of flavonoid inhibitory effects on enzyme activity

2019

Hamed, R.; Maharem, T.; Guneidy, R.; Emam, M.; Abdel Karim, G.

Physiol. Entomol.

44

187-199

760092

29779193

Functional role of Tyr12 in the catalytic activity of novel zeta-like glutathione S-transferase from Acidovorax sp. KKS102

2018

Shehu, D.; Alias, Z.

Protein J.

37

261-269

763778

34290951

A novel mycothiol-dependent thiol-disulfide reductase in Corynebacterium glutamicum involving oxidative stress resistance

2021

Liu, Y.; Li, X.; Luo, J.; Su, T.; Si, M.; Chen, C.

3 Biotech

11

372

764056

-

Characterization of an interesting selenium-dependent glutathione peroxidase (Se-GPx) protecting cells against environmental stress The Camelus dromedarius erythrocytes Se-GPx

2019

Chafik, A.; Essamadi, A.; Celik, S.; Solak, K.; Mavi, A.

Biocatal. Agricult. Biotechnol.

18

101000

764281

30385227

Design, synthesis, and biological evaluation of histone deacetylase inhibitors possessing glutathione peroxidase-like and antioxidant activities against Alzheimers disease

2018

Hu, J.; An, B.; Pan, T.; Li, Z.; Huang, L.; Li, X.

Bioorg. Med. Chem.

26

5718-5729

764731

31338075

Molecular mechanisms of AhpC in resistance to oxidative stress in Burkholderia thailandensis

2019

Zhang, B.; Gu, H.; Yang, Y.; Bai, H.; Zhao, C.; Si, M.; Su, T.; Shen, X.

Front. Microbiol.

10

1483

765064

32532818

Plasticity of the peroxidase AhpC links multiple substrates to diverse disulfide-reducing pathways in Shewanella oneidensis

2020

Feng, X.; Guo, K.; Gao, H.

J. Biol. Chem.

295

11118-11130

765808

30181584

Identification of a dioxin-responsive oxylipin signature in roots of date palm involvement of a 9-hydroperoxide fatty acid reductase, caleosin/peroxygenase PdPXG2

2018

Hanano, A.; Shaban, M.; Almousally, I.; Murphy, D.J.

Sci. Rep.

8

13181

Links to other databases for cumene hydroperoxide

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