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Ligand D-erythrulose

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Natural Substrate (2 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.1.1.162

D-erythrulose + NAD(P)+ = ?

286088

-

2.7.1.210

ATP + D-erythrulose = ADP + D-erythrulose 4-phosphate

736313

-

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

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Show Natural Product (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.1.1.403

D-threitol + NAD+ = D-erythrulose + NADH + H+

0

-

Substrate in Enzyme-catalyzed Reactions (5 results)

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Show Substrate (5 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.1.1.162

D-erythrulose + NAD(P)+ = ?

286088

-

1.1.1.162

D-erythrulose + NAD(P)H = D-threitol + NAD(P)+

286091, 286092, 286087, 286086, 286088

-

1.1.1.162

D-erythrulose + NADH + H+ = D-threitol + NAD+

286088, 286086, 286087

-

1.1.1.162

3 entries

2.7.1.209

ATP + D-erythrulose = ADP + D-erythrulose 4-phosphate

736313

-

2.7.1.210

ATP + D-erythrulose = ADP + D-erythrulose 4-phosphate

736313

-

Product in Enzyme-catalyzed Reactions (4 results)

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Show Product (4 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.1.1.10

DL-threitol + NADP+ = D-erythrulose + NADPH

287033

-

1.1.1.403

D-threitol + NAD+ = D-erythrulose + NADH + H+

0

-

5.3.1.14

D-erythrose = D-erythrulose + D-threose

0

-

5.3.1.14

D-threose = D-erythrulose + D-erythrose

0

-

5.3.1.14

2 entries

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (3 results)

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Show Turnover Number (3 entries)

EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

2.7.1.209

1.6

-

pH and temperature not specified in the publication

736313

2.7.1.210

0.091

-

pH and temperature not specified in the publication

736313

2.7.1.210

2.88

-

pH and temperature not specified in the publication

736313

2.7.1.210

2 entries

K_M Value (6 results)

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Show KM Value (6 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

1.1.1.162

0.11

-

-

286091

1.1.1.162

0.36

-

with NADH

286086

1.1.1.162

0.38

-

-

286088

1.1.1.162

3 entries

2.7.1.209

0.0106

-

pH and temperature not specified in the publication

736313

2.7.1.210

0.0046

-

pH and temperature not specified in the publication

736313

2.7.1.210

0.396

-

pH and temperature not specified in the publication

736313

2.7.1.210

2 entries

References & Links

Literature References (7)

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Show Reference (7 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

286086

6292658

D-Erythrulose reductase from beef liver

1982

Uehara, K.; Hosomi, S.

Methods Enzymol.

89

232-237

286087

4152124

Studies on D-tetrose metabolism. IV. Purification and some properties of D-erythrulose reductase from beef liver

1974

Uehara, K.; Tanimoto, T.; Sato, H.

J. Biochem.

75

333-345

286088

7358641

Studies on D-tetrose metabolism. Crystallization and properties of D-erythrulose reductase from chicken liver

1980

Uehara, K.; Mannen, S.; Hosomi, S.; Miyashita, T.

J. Biochem.

87

47-55

286091

9538249

D-erythrulose reductase can also reduce diacetyl: further purification and characterization of D-erythrulose reductase from chicken liver

1998

Maeda, M.; Hosomi, S.; Mizoguchi, T.; Nishihara, T.

J. Biochem.

123

602-606

286092

4091279

Methods for enzymatic and colorimetric determinations of D-erythrulose (D-tetrulose)

1985

Morii, K.; Hosomi, S.; Terada, T.; Mizoguchi, T.

Anal. Biochem.

151

188-191

287033

11306103

Molecular cloning, expression and tissue distribution of hamster diacetyl reductase. Identity with L-xylulose reductase

2001

Ishikura, S.; Isaji, T.; Usami, N.; Kitahara, K.; Nakagawa, J.; Hara, A.

Chem. Biol. Interact.

130-132

879-889

736313

26560079

A general strategy for the discovery of metabolic pathways: D-threitol, L-threitol, and erythritol utilization in Mycobacterium smegmatis

2015

Huang, H.; Carter, M.S.; Vetting, M.W.; Al-Obaidi, N.; Patskovsky, Y.; Almo, S.C.; Gerlt, J.A.

J. Am. Chem. Soc.

137

14570-14573

Links to other databases for D-erythrulose

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Show Links (1 entry)

ChEBI

PubChem