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Ligand Amine

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Natural Substrate (2 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.1.1.49

S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + an N-methylamine

441354, 441356

-

2.8.2.3

3'-phosphoadenylyl sulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate

690752

-

Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Substrate (2 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.1.1.49

S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + an N-methylamine

441354, 441356

-

2.8.2.3

3'-phosphoadenylyl sulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate

690752

-

Product in Enzyme-catalyzed Reactions (2 results)

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Show Product (2 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.4.3.4

RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2

0

-

3.4.11.2

amino acid amides + H2O = amine + amino acid

35884

-

Activator in Enzyme-catalyzed Reactions (2 results)

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Show Activating Compound (2 entries)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

1.1.2.B3

the enzymatic activity of the mutant enzyme in the artificial dye test with N-methylphenazonium methyl sulfate (PMS) and 2,6-dichlorophenol indophenol (DCPIP) at pH 9 does not depend on an activating amine which is essential for wild type activity under these condition

690646

-

1.2.1.49

several amines stimulate activity

655211

-

Inhibitor in Enzyme-catalyzed Reactions (4 results)

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Show Inhibitors (4 entries)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

3.2.1.33

-

171389

-

3.2.1.33

noncompetitive with glycogen phosphorylase limit dextrin, competitive with glucose; polyhydroxyamines, mechanism of inhibition; protonated, hydroxylalkyl-substituted, noncompetitive, mechanism of inhibition

171386

-

3.2.1.33

protonated, hydroxylalkyl-substituted, noncompetitive, mechanism of inhibition

171379

-

3.2.1.33

3 entries

3.4.24.19

-

31042

-

Enzyme Kinetic Parameters

References & Links

Literature References (10)

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Show Reference (10 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

31042

3533405

Partial purification and characterization of a procollagen C-proteinase from the culture medium of mouse fibroblasts

1986

Kessler, E.; Adar, R.; Goldberg, B.; Niece, R.

Coll. Relat. Res.

6

249-266

35884

5938935

An aminopeptidase occurring in pig kidney. II. A study on the mechanism of the hydrolysis

1966

Wachsmuth, E.D.; Fritze, I.; Pfleiderer, G.

Biochemistry

5

175-182

171379

5805288

Purification and properties of rabbit muscle amylo-1,6-glucosidase-oligo-1,4->1,4-transferase

1969

Nelson, T.E.; Kolb, E.; Larner, J.

Biochemistry

8

1419-1428

171386

269742

Amylo-1,6-glucosidase/4-alpha-glucanotransferase: use of reversible substrate model inhibitors to study the binding and active sites of rabbit muscle debranching enzyme

1977

Gillard, B.K.; Nelson, T.E.

Biochemistry

16

3978-3987

171389

4335607

New aspects of glycogen metabolism

1971

Ryman, B.E.; Whelan, W.J.

Adv. Enzymol. Relat. Areas Mol. Biol.

34

285-443

441354

3949799

Amine N-methyltransferases from rabbit liver

1986

Ansher, S.S.; Jakoby, W.B.

J. Biol. Chem.

261

3996-4001

441356

11322482

Arylamine N-methyltransferase and thiol methyltransferase activities in cholestatic rat liver induced by common bile duct ligation

2001

Kim, Y.H.; Joo, I.

Exp. Mol. Med.

33

23-28

655211

12604221

Methylglyoxal metabolism and diabetic complications: roles of aldose reductase, glyoxalase-I, betaine aldehyde dehydrogenase and 2-oxoaldehyde dehydrogenase

2003

Vander Jagt, D.L.; Hunsaker, L.A.

Chem. Biol. Interact.

143-144

341-351

690646

19224199

Quinoprotein ethanol dehydrogenase from Pseudomonas aeruginosa: the unusual disulfide ring formed by adjacent cysteine residues is essential for efficient electron transfer to cytochrome c550

2009

Mennenga, B.; Kay, C.W.; Goerisch, H.

Arch. Microbiol.

191

361-367

690752

18725199

Molecular cloning, expression, and characterization of mouse amine N-sulfotransferases

2008

Takahashi, S.; Sakakibara, Y.; Mishiro, E.; Kouriki, H.; Nobe, R.; Kurogi, K.; Yasuda, S.; Liu, M.C.; Suiko, M.

Biochem. Biophys. Res. Commun.

375

531-535

Links to other databases for Amine

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Show Links (1 entry)