Ligand ADP-mannose

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Basic Ligand Information

Molecular Structure
Picture of ADP-mannose (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C16H25N5O15P2
ADP-mannose
WFPZSXYXPSUOPY-RYRBFGMPSA-N
Synonyms:
ADP-alpha-D-mannopyranose, ADP-alpha-D-mannose, ADP-Man, ADPmannose, alpha-ADP-mannose

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ADPmannose + diphosphate = ATP + D-mannose 1-phosphate
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ADP-mannose + GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-dicis,octatrans-undecaprenol = ADP + D-Man-beta-(1->4)-GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-dicis,octatrans-undecaprenol
show the reaction diagram
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ADP-mannose + 2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate = ADP + 2-(2-O-(alpha-D-mannopyranosyl)-alpha-D-glucopyranosyl)-3-phospho-D-glycerate
show the reaction diagram
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ADP-alpha-D-mannose + alpha-L-glycero-D-manno-heptosyl-(1->5)-[(3-deoxy-alpha-D-manno-oct-2-ulopyranosylonate)-(2->4)]-(3-deoxy-alpha-D-manno-oct-2-ulopyranosylonate)-(2->6)-2-deoxy-2-[[(3R)-3-hydroxytetradecanoyl]amino]-3-O-[(3R)-3-hydroxytetradecanoyl]-4-O-phospho-beta-D-glucopyranosyl-(1->6)-2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-[[(3R)-3-hydroxytetradecanoyl]amino]-1-O-phosphono-alpha-D-glucopyranose = ? + ADP
show the reaction diagram
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ADPmannose + diphosphate = ATP + D-mannose 1-phosphate
show the reaction diagram
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ADP-mannose + phosphate = ADP + D-mannose 1-phosphate
show the reaction diagram
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ADP-mannose + H2O = AMP + D-mannose 1-phosphate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + alpha-D-mannose 1-phosphate = diphosphate + ADP-mannose
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.5
-
pH 7.5, 30°C
0.183
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pH 7.5

References & Links

Links to other databases for ADP-mannose

ChEBI
PubChem
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PubChem