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a dual-target-directed drug inhibiting MAO-B and antagonizing A2A receptors
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5 mM, 95% inhibition of heart phosphorylase Ib in the presence of 1 mM AMP, 30% inhibition of heart phosphorylase IIb
5 mM, 95% inhibition of heart phosphorylase Ib in the presence of 1 mM AMP, 30% inhibition of heart phosphorylase IIb
5 mM, 95% inhibition of heart phosphorylase Ib in the presence of 1 mM AMP, 30% inhibition of heart phosphorylase IIb
5 mM, 95% inhibition of heart phosphorylase Ib in the presence of 1 mM AMP, 30% inhibition of heart phosphorylase IIb
5 mM, 95% inhibition of heart phosphorylase Ib in the presence of 1 mM AMP, 30% inhibition of heart phosphorylase IIb
5 mM, 95% inhibition of heart phosphorylase Ib in the presence of 1 mM AMP, 30% inhibition of heart phosphorylase IIb
5 mM, 95% inhibition of heart phosphorylase Ib in the presence of 1 mM AMP, 30% inhibition of heart phosphorylase IIb
5 mM, complete inhibition of phosphorylase b, strong inhibition of phosphorylases ab and a
5 mM, complete inhibition of phosphorylase b, strong inhibition of phosphorylases ab and a
5 mM, complete inhibition of phosphorylase b, strong inhibition of phosphorylases ab and a
5 mM, complete inhibition of phosphorylase b, strong inhibition of phosphorylases ab and a
5 mM, complete inhibition of phosphorylase b, strong inhibition of phosphorylases ab and a
5 mM, complete inhibition of phosphorylase b, strong inhibition of phosphorylases ab and a
5 mM, complete inhibition of phosphorylase b, strong inhibition of phosphorylases ab and a
inhibition of the liver enzyme, counteracted by AMP
inhibition of the liver enzyme, counteracted by AMP
inhibition of the liver enzyme, counteracted by AMP
inhibition of the liver enzyme, counteracted by AMP
inhibition of the liver enzyme, counteracted by AMP
inhibition of the liver enzyme, counteracted by AMP
inhibition of the liver enzyme, counteracted by AMP
strong inhibition of muscle enzyme
strong inhibition of muscle enzyme
strong inhibition of muscle enzyme
strong inhibition of muscle enzyme
strong inhibition of muscle enzyme
strong inhibition of muscle enzyme
strong inhibition of muscle enzyme
1 mM, 86% inhibition of the 116000 Da enzyme, 57% inhibition of the 90000 Da enzyme
-
about 25% inhibition at 0.01 mM
-
20-80% inhibition when present at 0.1-1 mM
-
might inhibit the enzyme
-
competitive to ATP, 75% inhibition at 20 mM
-
21% inhibition at 0.1 mM
-
ATM/ATR inhibition sensitizes cancer cells to ionizing radiation, nonspecific inhibitor for ATM and ATR; ATM/ATR inhibition sensitizes cancer cells to ionizing radiation, nonspecific inhibitor for ATM and ATR
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uncompetitive inhibition
-
noncompetitive, dog heart
-
50 mM, 30% inhibition of soluble enzyme
-
two caffeine molecules bind to CrChi1 in subsites -1 to +1 in the substrate-binding domain, binding structure, overview
two caffeine molecules bind to CrChi1 in subsites -1 to +1 in the substrate-binding domain, binding structure, overview
weak competitive inhibitor
-
inhibits cAMP accumulation by ACB and ACG. None among ACA, ACB and ACG is a direct target for the inhibitory effects of caffeine
-
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