Ligand 4-methylaminobutanoate
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Basic Ligand Information
Molecular Structure

C5H11NO2
4-methylaminobutanoate
AOKCDAVWJLOAHG-UHFFFAOYSA-N
gamma-N-methylaminobutyric acid
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (2 results)
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4-methylaminobutanoate + O2 + H2O = 4-aminobutanoate + formaldehyde + H2O2
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4-methylaminobutanoate + O2 + H2O = succinate semialdehyde + methylamine + H2O2
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Product in Enzyme-catalyzed Reactions (2 results)
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N-methylpyrrolidone + = gamma-N-methylaminobutyric acid
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2,6-dihydroxypseudooxynicotine + H2O = 2,6-dihydroxypyridine + 4-methylaminobutanoate
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Enzyme Kinetic Parameters
kcat Value (Turnover Number) (2 results)
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800
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pH 10, temperature not specified in the publication
KM Value (2 results)
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0.14
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pH 10, temperature not specified in the publication
References & Links
Literature References (2)
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A novel gamma-N-methylaminobutyrate demethylating oxidase involved in catabolism of the tobacco alkaloid nicotine by Arthrobacter nicotinovorans pAO1
2004
Chiribau, C.; Sandu, C.; Fraaije, M.; Schiltz, E.; Brandsch, R.
Eur. J. Biochem.
271
4677-4684
Final steps in the catabolism of nicotine
2006
Chiribau, C.; Mihasan, M.; Ganas, P.; Igloi, G.; Artenie, V.; Brandsch, R.
FEBS J.
273
1528-1536
Links to other databases for 4-methylaminobutanoate