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Ligand guanine527 in 16S rRNA

Basic Ligand Information

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Natural Substrate (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.1.1.170

S-adenosyl-L-methionine + guanine527 in 16S rRNA = S-adenosyl-L-homocysteine + N7-methylguanine527 in 16S rRNA

706725, 704273, 733472, 779252

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Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Substrate (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.1.1.170

S-adenosyl-L-methionine + guanine527 in 16S rRNA = S-adenosyl-L-homocysteine + N7-methylguanine527 in 16S rRNA

706725, 704273, 704222, 705767, 733472, 779252

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Enzyme Kinetic Parameters

References & Links

Literature References (6)

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Show Reference (6 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

704222

19816520

Activation of secondary metabolite-biosynthetic gene clusters by generating rsmG mutations in Streptomyces griseus

2009

Tanaka, Y.; Tokuyama, S.; Ochi, K.

J. Antibiot.

62

669-673

704273

17573471

Identification of the RsmG methyltransferase target as 16S rRNA nucleotide G527 and characterization of Bacillus subtilis rsmG mutants

2007

Nishimura, K.; Johansen, S.K.; Inaoka, T.; Hosaka, T.; Tokuyama, S.; Tahara, Y.; Okamoto, S.; Kawamura, F.; Douthwaite, S.; Ochi, K.

J. Bacteriol.

189

6068-6073

705767

17238915

Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria

2007

Okamoto, S.; Tamaru, A.; Nakajima, C.; Nishimura, K.; Tanaka, Y.; Tokuyama, S.; Suzuki, Y.; Ochi, K.

Mol. Microbiol.

63

1096-1106

706725

19622680

Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG

2009

Gregory, S.T.; Demirci, H.; Belardinelli, R.; Monshupanee, T.; Gualerzi, C.; Dahlberg, A.E.; Jogl, G.

RNA

15

1693-1704

733472

24968035

Impairing methylations at ribosome RNA, a point mutation-dependent strategy for aminoglycoside resistance: The rsmG case

2014

Benitez-Paez, A.; Cardenas-Brito, S.; Corredor, M.; Villarroya, M.; Armengod, M.E.

Biomedica

34

41-49

779252

35514586

RsmG forms stable complexes with premature small subunit rRNA during bacterial ribosome biogenesis

2020

Abedeera, S.M.; Hawkins, C.M.; Abeysirigunawardena, S.C.

RSC Adv.

10

22361-22369

Links to other databases for guanine527 in 16S rRNA

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Show Links (1 entry)