Any feedback?
Please rate this page
(ligand.php)
(0/150)

BRENDA support

Ligand (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H8O4
(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate
HMXOGGUFCBUALL-AATRIKPKSA-N
Synonyms:
(E)-2'-hydroxybenzylidenepyruvate, trans-o-hydroxybenzylidenepyruvate, trans-o-hydroxybenzylidene pyruvic acid

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-hydroxychromene-2-carboxylic acid = trans-o-hydroxybenzylidene pyruvic acid
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-hydroxy-2H-chromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
i.e. (E)-2'-hydroxybenzylidenepyruvate
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
19
-
pH 7.0, 25°C, recombinant enzyme
19
-
pH 7.0, 25°C

KM Value (5 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.138
-
pH 7.0, 25°C, recombinant enzyme
0.138
-
pH 7.0, 25°C

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.136
-
pH 7.0, 25°C, recombinant enzyme
0.136
-
pH 7.0, 25°C

References & Links

Links to other databases for (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate

ChEBI
PubChem
ChEBI
PubChem