Ligand cobyrinic acid c-monoamide
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Basic Ligand Information
Molecular Structure

C45H61CoN5O13
cobyrinic acid c-monoamide
NJNUXMOGJWUPPV-OKJGWHJPSA-M
cobyrinate c-monamide, cobyrinate c-monoamide
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (3 results)
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ATP + cobyrinate c-monoamide + L-glutamine + H2O = ADP + phosphate + cobyrinate a,c-diamide + L-glutamate
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cobyrinic acid c-monoamide + ATP + glutamine = cobyrinic acid a,c-diamide + ADP + phosphate + glutamate
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cobyrinic acid c-monoamide + ATP + NH4+ = cobyrinic acid a,c-diamide + ADP + phosphate
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Enzyme Kinetic Parameters
kcat Value (Turnover Number) (4 results)
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0.008
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mutant enzyme Y46A
0.04
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mutant enzyme D97N
0.057
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mutant enzyme L47A
KM Value (4 results)
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0.0003
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mutant enzyme D97N
0.00041
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wild-type enzyme
0.0027
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mutant enzyme L47A
0.011
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mutant enzyme Y46A
References & Links
Literature References (2)
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Purification and characterization of cobyrinic acid a,c-diamide synthase from Pseudomonas denitrificans
1990
Debussche, L.; Thibaut, D.; Cameron, B.; Crouzet, J.; Blanche, F.
J. Bacteriol.
172
6239-6244
Mechanism of cobyrinic acid a,c-diamide synthetase from Salmonella typhimurium LT2
2004
Fresquet, V.; Williams, L.; Raushel, F.M.
Biochemistry
43
10619-10627
Links to other databases for cobyrinic acid c-monoamide