Ligand 2-oxo-4-phenylbutanoic acid

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Basic Ligand Information

Molecular Structure
Picture of 2-oxo-4-phenylbutanoic acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H10O3
2-oxo-4-phenylbutanoic acid
PPKAIMDMNWBOKN-UHFFFAOYSA-N
Synonyms:
2-oxo-4-phenyl-3-butanoate, 2-oxo-4-phenyl-butanoic acid, 2-oxo-4-phenyl-butyric acid, 2-oxo-4-phenylbutanoate, 2-oxo-4-phenylbutyrate, 2-oxo-4-phenylbutyric acid, 4-phenyl-2-oxobutanoic acid, homophenylpyruvate

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (17 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-oxo-4-phenylbutanoate + NADPH + H+ = (R)-2-hydroxy-4-phenylbutanoate + NADPH
show the reaction diagram
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2-oxo-4-phenylbutanoic acid + O2 = ?
show the reaction diagram
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L-Lys + 2-oxo-4-phenyl-butanoic acid = L-homophenylalanine + 2-keto-6-aminocaproate
show the reaction diagram
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2-oxo-4-phenylbutanoic acid = 3-phenylpropionaldehyde + CO2
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(E)-2-oxo-4-phenyl-3-butenoate + NADH = 2-oxo-4-phenyl-3-butanoate + NAD+
show the reaction diagram
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L-homophenylalanine + H2O + NADH + H+ = 2-oxo-4-phenylbutanoate + NH3 + NAD+
show the reaction diagram
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DL-homophenylalanine + H2O + O2 = homophenylpyruvate + NH3 + H2O2
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (5 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.17
-
pH 7.5, 25°C

KM Value (5 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.035
-
pH 7.5, 25°C

References & Links

Links to other databases for 2-oxo-4-phenylbutanoic acid

ChEBI
PubChem
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PubChem