Ligand angelicin
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Basic Ligand Information
Molecular Structure

C11H6O3
angelicin
XDROKJSWHURZGO-UHFFFAOYSA-N
2H-furo[2,3-h][1]benzopyran-2-one
Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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(+)-columbianetin + [reduced NADPH-hemoprotein reductase] + O2 = angelicin + acetone + [oxidized NADPH-hemoprotein reductase] + H2O
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Product in Enzyme-catalyzed Reactions (1 result)
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(+)-columbianetin + [reduced NADPH-hemoprotein reductase] + O2 = angelicin + acetone + [oxidized NADPH-hemoprotein reductase] + H2O
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Inhibitor in Enzyme-catalyzed Reactions (2 results)
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39.0% inhibition at 0.01 mM
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71.7% inhibition at 0.01 mM
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Enzyme Kinetic Parameters
References & Links
Literature References (1)
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Inhibition of the aldehyde dehydrogenase 1/2 family by psoralen and coumarin derivatives
2017
Buchman, C.D.; Hurley, T.D.
J. Med. Chem.
60
2439-2455
Links to other databases for angelicin