Ligand hypoxia-inducible factor-(4R)-4-hydroxy-L-proline

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Basic Ligand Information

Molecular Structure
Picture of hypoxia-inducible factor-(4R)-4-hydroxy-L-proline (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C67H101N13O23R2S2
hypoxia-inducible factor-(4R)-4-hydroxy-L-proline
Synonyms:
hypoxia-inducible factor-alpha-trans-4-hydroxy-L-proline, hypoxia-inducible factor-trans-4-hydroxy-L-proline, hypoxia-inducible factor-trans-4-hydroxy-L-proline peptide, hypoxia-inducible factor1alpha C-terminal oxygen-dependent degradation domain-trans-4-hydroxy-L-proline, hypoxia-inducible factor1alpha C-terminal oxygen dependent degradation domain-trans-4-hydroxy-L-proline, hypoxia-inducible factor alpha trans-4-hydroxy-L-proline, hypoxia-inducible factor trans-4-hydroxy-L-proline, hypoxia inducible factor trans-4-hydroxy-L-proline

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
hypoxia-inducible factor L-proline + 2-oxoglutarate + O2 = hypoxia inducible factor trans-4-hydroxy-L-proline + succinate + CO2
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
hypoxia-inducible factor1alpha C-terminal oxygen dependent degradation domain-L-proline + 2-oxoglutarate + O2 = hypoxia-inducible factor1alpha C-terminal oxygen dependent degradation domain-trans-4-hydroxy-L-proline + succinate + CO2
show the reaction diagram
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Enzyme Kinetic Parameters

Links to other databases for hypoxia-inducible factor-(4R)-4-hydroxy-L-proline

ChEBI
PubChem
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