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Ligand hypoxia-inducible factor-(4R)-4-hydroxy-L-proline
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Basic Ligand Information
hypoxia-inducible factor-alpha-trans-4-hydroxy-L-proline, hypoxia-inducible factor-trans-4-hydroxy-L-proline, hypoxia-inducible factor-trans-4-hydroxy-L-proline peptide, hypoxia-inducible factor1alpha C-terminal oxygen-dependent degradation domain-trans-4-hydroxy-L-proline, hypoxia-inducible factor1alpha C-terminal oxygen dependent degradation domain-trans-4-hydroxy-L-proline, hypoxia-inducible factor alpha trans-4-hydroxy-L-proline, hypoxia-inducible factor trans-4-hydroxy-L-proline, hypoxia inducible factor trans-4-hydroxy-L-proline
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In Vivo Product in Enzyme-catalyzed Reactions (4 results)
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EC NUMBER 
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
hypoxia-inducible factor L-proline + 2-oxoglutarate + O2 = hypoxia inducible factor trans-4-hydroxy-L-proline + succinate + CO2
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hypoxia-inducible factor-L-proline + 2-oxoglutarate + O2 = hypoxia-inducible factor-(4R)-4-hydroxy-L-proline + succinate + CO2
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hypoxia-inducible factor-alpha-L-proline + 2-oxoglutarate + O2 = hypoxia-inducible factor-alpha-trans-4-hydroxy-L-proline + succinate + CO2
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hypoxia-inducible factor-L-proline + 2-oxoglutarate + O2 = hypoxia-inducible factor-trans-4-hydroxy-L-proline + succinate + CO2
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Product in Enzyme-catalyzed Reactions (9 results)
EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
hypoxia-inducible factor L-proline + 2-oxoglutarate + O2 = hypoxia inducible factor trans-4-hydroxy-L-proline + succinate + CO2
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hypoxia-inducible factor alpha L-proline + 2-oxoglutarate + O2 = hypoxia-inducible factor alpha trans-4-hydroxy-L-proline + succinate + CO2
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hypoxia-inducible factor L-proline + 2-oxoglutarate + O2 = hypoxia-inducible factor trans-4-hydroxy-L-proline + succinate + CO2
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hypoxia-inducible factor-L-proline + 2-oxoglutarate + O2 = hypoxia-inducible factor-(4R)-4-hydroxy-L-proline + succinate + CO2
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hypoxia-inducible factor-alpha-L-proline + 2-oxoglutarate + O2 = hypoxia-inducible factor-alpha-trans-4-hydroxy-L-proline + succinate + CO2
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hypoxia-inducible factor-L-proline + 2-oxoglutarate + O2 = hypoxia-inducible factor-trans-4-hydroxy-L-proline + succinate + CO2
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hypoxia-inducible factor-L-proline peptide + 2-oxoglutarate + O2 = hypoxia-inducible factor-trans-4-hydroxy-L-proline peptide + succinate + CO2
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hypoxia-inducible factor1alpha C-terminal oxygen-dependent degradation domain-L-proline + 2-oxoglutarate + O2 = hypoxia-inducible factor1alpha C-terminal oxygen-dependent degradation domain-trans-4-hydroxy-L-proline + succinate + CO2
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hypoxia-inducible factor1alpha C-terminal oxygen dependent degradation domain-L-proline + 2-oxoglutarate + O2 = hypoxia-inducible factor1alpha C-terminal oxygen dependent degradation domain-trans-4-hydroxy-L-proline + succinate + CO2
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Enzyme Kinetic Parameters
References & Links
Literature References (0)
Links to other databases for hypoxia-inducible factor-(4R)-4-hydroxy-L-proline
EXTERNAL LINKS
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Release 2026.1 (March 2026)
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