Ligand 5-fluorotryptamine

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Basic Ligand Information

Molecular Structure
Picture of 5-fluorotryptamine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H11FN2
5-fluorotryptamine
ZKIORVIXEWIOGB-UHFFFAOYSA-N
Synonyms:
2-(5-fluoro-1H-indol-3-yl)ethanamine, 5-fluoro-tryptamine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5-fluoro-L-tryptophan = 5-fluorotryptamine + CO2
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
a drug causing head-twitch response, IC50: 0.00018 mM
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (5 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

IC50 Value (3 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.0002
-
in phosphate buffer pH 7.4, at 37°C
0.00079
-
IC50: 0.00079 mM
0.00018
-
a drug causing head-twitch response, IC50: 0.00018 mM

References & Links

Links to other databases for 5-fluorotryptamine

ChEBI
PubChem
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PubChem