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0.0027
-
pH 7.0, temperature not specified in the publication, mutant R267A
0.0035
-
pH 7.0, temperature not specified in the publication, mutant F270A
0.021
-
pH 7.0, temperature not specified in the publication, wild-type enzyme
0.038
-
pH 7.0, temperature not specified in the publication, mutant K89A
0.045
-
pH 7.5, 24°C, recombinant mutant T155A/T156A
0.125
-
pH 7.5, 24°C, recombinant mutant T155A
0.137
-
pH 7.5, 24°C, recombinant mutant T152A
0.15
-
pH 7.5, 24°C, recombinant mutant R382A
0.213
-
pH 7.5, 24°C, recombinant mutant T156A
0.228
-
pH 7.5, 24°C, recombinant mutant R382K
2.17
-
pH 7.5, 24°C, recombinant mutant G154P
2.62
-
pH 7.5, 21°C, recombinant His-tagged enzyme
46.67
-
pH 7.5, 24°C, recombinant mutant G157P
120
-
pH 7.5, 24°C, recombinant wild-type enzyme
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0.0028
-
pH 7.0, temperature not specified in the publication, wild-type enzyme
0.0166
-
pH 7.0, temperature not specified in the publication, mutant R267A
0.0197
-
pH 7.0, temperature not specified in the publication, mutant F270A
0.0433
-
pH 7.0, temperature not specified in the publication, mutant K89A
0.0219
-
pH 7.5, 21°C, recombinant His-tagged enzyme
0.044
-
pH 7.5, 24°C, recombinant wild-type enzyme
0.057
-
pH 7.5, 24°C, recombinant mutant R382A
0.066
-
pH 7.5, 24°C, recombinant mutant R382K
0.08
-
pH 7.5, 24°C, recombinant mutant G157P
0.087
-
pH 7.5, 24°C, recombinant mutant T155A
0.12
-
pH 7.5, 24°C, recombinant mutant G154P
0.14
-
pH 7.5, 24°C, recombinant mutant T156A
0.28
-
pH 7.5, 24°C, recombinant mutant T155A/T156A
0.88
-
pH 7.5, 24°C, recombinant mutant T152A
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Menaquinone (vitamin K2) biosynthesis: conversion of o-succinylbenzoic acid to 1,4-dihydroxy-2-naphthoic acid by Mycobacterium phlei enzymes
1979
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4-(2'-Carboxyphenyl)-4-oxobutyryl coenzyme A ester, an intermediate in vitamin K2 (menaquinone) biosynthesis
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Enzymatic synthesis of the coenzyme A ester of o-succinylbenzoic acid, an intermediate in menaquinone (vitamin K2) biosynthesis
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Recombinent plasmids containing menaquinone biosynthetic genes of Escherichia coli
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Shaw, D.J.; Robinson, E.C.; Meganathan, R.; Bentley, R.; Guest, J.R.
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Enzymatic synthesis, characterization, and metabolism of the coenzyme A ester of o-succinylbenzoic acid, an intermediate in menaquinone (vitamin K2) biosynthesis
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Heide, L.; Arendt, S.; Leistner, E.
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The menD and menE homologs code for 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylate synthase and O-succinylbenzoic acid-CoA synthase in the phylloquinone biosynthetic pathway of Synechocystis sp. PCC 6803
2003
Johnson, T.W.; Naithani, S.; Stewart, C.Jr.; Zybailov, B.; Jones, A.D.; Golbeck, J.H.; Chitnis, P.R.
Biochim. Biophys. Acta
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O-Succinylbenzoate:coenzyme A ligase, an enzyme involved in menaquinone (vitamin K2) biosynthesis displays braod specificity
1991
Siewecke, H.J.; Leistner, E.
Z. Naturforsch. C
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Vitamin K2 (menaquinone) biosynthesis in Escherichia coli: evidence for the presence of an essential histidine residue in o-succinylbenzoyl coenzyme A synthetase
1997
Bhattacharyya, D.K.; Kwon, O.; Meganathan, R.
J. Bacteriol.
179
6061-6065
Menaquinone (vitamin K2) biosynthesis: overexpression, purification, and properties of o-succinylbenzoyl-coenzyme A synthetase from Escherichia coli
1996
Kwon, O.; Bhattacharyya, D.K.; Meganathan, R.
J. Bacteriol.
178
6778-6781
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o-Succinylbenzoate:coenzyme A ligase from anthraquinone producing cell suspension cultures of Galium mollugo
1992
Sieweke, H.J.; Leistner, E.
Phytochemistry
31
2329-2335
Evolution of enzymatic activity in the enolase superfamily: structure of o-succinylbenzoate synthase from Escherichia coli in complex with Mg2+ and o-succinylbenzoate
2000
Thompson, T.B.; Garrett, J.B.; Taylor, E.A.; Meganathan, R.; Gerlt, J.A.; Rayment, I.
Biochemistry
39
10662-10676
Evolution of enzymatic activity in the enolase superfamily: structural and mutagenic studies of the mechanism of the reaction catalyzed by o-succinylbenzoate synthase from Escherichia coli
2003
Klenchin, V.A.; Taylor Ringia, E.A.; Gerlt, J.A.; Rayment, I.
Biochemistry
42
14427-14433
Bacillus anthracis o-succinylbenzoyl-CoA synthetase: reaction kinetics and a novel inhibitor mimicking its reaction intermediate
2008
Tian, Y.; Suk, D.H.; Cai, F.; Crich, D.; Mesecar, A.D.
Biochemistry
47
12434-12447
Mechanism-based inhibitors of MenE, an acyl-CoA synthetase involved in bacterial menaquinone biosynthesis
2008
Lu, X.; Zhang, H.; Tonge, P.J.; Tan, D.S.
Bioorg. Med. Chem. Lett.
18
5963-5966
The AAE14 gene encodes the Arabidopsis o-succinylbenzoyl-CoA ligase that is essential for phylloquinone synthesis and photosystem-I function
2008
Kim, H.U.; van Oostende, C.; Basset, G.J.; Browse, J.
Plant J.
54
272-283
CoA adducts of 4-oxo-4-phenylbut-2-enoates: inhibitors of MenB from the M. tuberculosis menaquinone biosynthesis pathway
2011
Li, X.; Liu, N.; Zhang, H.; Knudson, S.E.; Li, H.J.; Lai, C.T.; Simmerling, C.; Slayden, R.A.; Tonge, P.J.
ACS Med. Chem. Lett.
2
818-823
Active site binding and catalytic role of bicarbonate in 1,4-dihydroxy-2-naphthoyl coenzyme a synthases from vitamin K biosynthetic pathways
2012
Sun, Y.; Song, H.; Li, J.; Jiang, M.; Li, Y.; Zhou, J.; Guo, Z.
Biochemistry
51
4580-4589
Stable analogues of OSB-AMP: potent inhibitors of MenE, the o-succinylbenzoate-CoA synthetase from bacterial menaquinone biosynthesis
2012
Lu, X.; Zhou, R.; Sharma, I.; Li, X.; Kumar, G.; Swaminathan, S.; Tonge, P.J.; Tan, D.S.
ChemBioChem
13
129-136
Structural basis of the induced-fit mechanism of 1,4-dihydroxy-2-naphthoyl coenzyme A synthase from the crotonase fold superfamily
2013
Sun, Y.; Song, H.; Li, J.; Li, Y.; Jiang, M.; Zhou, J.; Guo, Z.
PLoS ONE
8
e63095
Structural basis for the ATP-dependent configuration of adenylation active site in Bacillus subtilis o-succinylbenzoyl-CoA synthetase
2015
Chen, Y.; Sun, Y.; Song, H.; Guo, Z.
J. Biol. Chem.
290
23971-23983
Show all BRENDA pathways known for o-succinylbenzoate
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